SOX2 is overexpressed in stem-like cells of human lung adenocarcinoma and augments the tumorigenicity. - Wikidata - awgldk - TriplyDB

SOX2 is overexpressed in stem-like cells of human lung adenocarcinoma and augments the tumorigenicity.

SOX2 is overexpressed in stem-like cells of human lung adenocarcinoma and augments the tumorigenicity.

http://www.wikidata.org/entity/Q34022836

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High expression of CD109 antigen regulates the phenotype of cancer stem-like cells/cancer-initiating cells in the novel epithelioid sarcoma cell line ESX and is related to poor prognosis of soft tissue sarcoma Cancer stem cells in small cell lung cancer Immune responses to human cancer stem-like cells/cancer-initiating cells The role of SOX2 in small cell lung cancer, lung adenocarcinoma and squamous cell carcinoma of the lung The Effect of MicroRNA-375 Overexpression, an Inhibitor of Helicobacter pylori-Induced Carcinogenesis, on lncRNA SOX2OT.YB-1 regulates Sox2 to coordinately sustain stemness and tumorigenic properties in a phenotypically distinct subset of breast cancer cells SOX2 expression is an early event in a murine model of EGFR mutant lung cancer and promotes proliferation of a subset of EGFR mutant lung adenocarcinoma cell lines.MAGE-A3 is highly expressed in a cancer stem cell-like side population of bladder cancer cells.Context-dependent function of the deubiquitinating enzyme USP9X in pancreatic ductal adenocarcinoma SOX2 regulates self-renewal and tumorigenicity of human melanoma-initiating cells.SOX2 gene regulates the transcriptional network of oncogenes and affects tumorigenesis of human lung cancer cells.Elevating SOX2 levels deleteriously affects the growth of medulloblastoma and glioblastoma cells.EGFR/Src/Akt signaling modulates Sox2 expression and self-renewal of stem-like side-population cells in non-small cell lung cancer.βArrestin-1 and Mcl-1 modulate self-renewal growth of cancer stem-like side-population cells in non-small cell lung cancer.ALDH1-high ovarian cancer stem-like cells can be isolated from serous and clear cell adenocarcinoma cells, and ALDH1 high expression is associated with poor prognosis Ovarian cancer stem cells are enriched in side population and aldehyde dehydrogenase bright overlapping population.Profiling gene promoter occupancy of Sox2 in two phenotypically distinct breast cancer cell subsets using chromatin immunoprecipitation and genome-wide promoter microarrays Identification of biological properties of intralymphatic tumor related to the development of lymph node metastasis in lung adenocarcinoma Autologous anti-SOX2 antibody responses reflect intensity but not frequency of antigen expression in small cell lung cancer.Dnajb8, a Member of the Heat Shock Protein 40 Family Has a Role in the Tumor Initiation and Resistance to Docetaxel but Is Dispensable for Stress Response.Mutations in TP53 increase the risk of SOX2 copy number alterations and silencing of TP53 reduces SOX2 expression in non-small cell lung cancer.Establishment and Analysis of Cancer Stem-Like and Non-Cancer Stem-Like Clone Cells from the Human Colon Cancer Cell Line SW480 Brother of the regulator of the imprinted site (BORIS) variant subfamily 6 is a novel target of lung cancer stem-like cell immunotherapy.Heat shock enhances the expression of cytotoxic granule proteins and augments the activities of tumor-associated antigen-specific cytotoxic T lymphocytes Cell proliferation and invasion ability of human choriocarcinoma cells lessened due to inhibition of Sox2 expression by microRNA-145.The chromosome 3q26 OncCassette: A multigenic driver of human cancer.Functional and molecular characterization of cancer stem-like cells in bladder cancer: a potential signature for muscle-invasive tumors.Cathepsin B and uPAR regulate self-renewal of glioma-initiating cells through GLI-regulated Sox2 and Bmi1 expression Expression of the Pluripotency Transcription Factor OCT4 in the Normal and Aberrant Mammary Gland Enhanced therapeutic effect of an antiangiogenesis peptide on lung cancer in vivo combined with salmonella VNP20009 carrying a Sox2 shRNA construct Triple negative breast cancer initiating cell subsets differ in functional and molecular characteristics and in γ-secretase inhibitor drug responses.Ectopically expressed variant form of sperm mitochondria-associated cysteine-rich protein augments tumorigenicity of the stem cell population of lung adenocarcinoma cells.SOX2 functions as a molecular rheostat to control the growth, tumorigenicity and drug responses of pancreatic ductal adenocarcinoma cells Epigenetic modifications promote the expression of the orphan nuclear receptor NR0B1 in human lung adenocarcinoma cells.Plasticity of lung cancer stem-like cells is regulated by the transcription factor HOXA5 that is induced by oxidative stress.Sox2 inhibits Wnt-β-catenin signaling and metastatic potency of cisplatin-resistant lung adenocarcinoma cells.The stemness phenotype model.The hitchhikers guide to cancer stem cell theory: markers, pathways and therapy.Constitutive expression and activation of stress response genes in cancer stem-like cells/tumour initiating cells: potent targets for cancer stem cell therapy.Therapy-induced enrichment of putative lung cancer stem-like cells.

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P2860

SOX2 is overexpressed in stem-like cells of human lung adenocarcinoma and augments the tumorigenicity.

http://www.wikidata.org/entity/Q34022836

description

2011 nî lūn-bûn

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2011 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

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2011 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

SOX2 is overexpressed in stem- ...... d augments the tumorigenicity.

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SOX2 is overexpressed in stem- ...... d augments the tumorigenicity.

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SOX2 is overexpressed in stem- ...... d augments the tumorigenicity.

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SOX2 is overexpressed in stem- ...... d augments the tumorigenicity.

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SOX2 is overexpressed in stem- ...... d augments the tumorigenicity.

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SOX2 is overexpressed in stem- ...... d augments the tumorigenicity.

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SOX2 is overexpressed in stem- ...... d augments the tumorigenicity.

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LABINVEST.2011.140

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Laboratory Investigation

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SOX2 is overexpressed in stem- ...... d augments the tumorigenicity.

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Akari Takahashi

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Hiroki Takahashi

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Hiroko Asanuma

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Masaki Murase

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Munehide Nakatsugawa

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Noriyuki Sato

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Rena Morita

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Satoko Inoda

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Tadashi Hasegawa

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Toru Kondo

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P2860

Evidence that SOX2 overexpression is oncogenic in the lung

SOX2 is an oncogene activated by recurrent 3q26.3 amplifications in human lung squamous cell carcinomas

The molecular mechanism governing the oncogenic potential of SOX2 in breast cancer

Highly tumorigenic lung cancer CD133+ cells display stem-like features and are spared by cisplatin treatment

ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome

Serological identification of embryonic neural proteins as highly immunogenic tumor antigens in small cell lung cancer

Prospective identification of tumorigenic breast cancer cells

Identification of human brain tumour initiating cells

A cell initiating human acute myeloid leukaemia after transplantation into SCID mice

Vertebrate neurogenesis is counteracted by Sox1-3 activity

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labinvest.2011.140

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1796-1804

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