Identification of chemical compounds that induce HIF-1alpha activity. - Wikidata - awgldk - TriplyDB

Identification of chemical compounds that induce HIF-1alpha activity.

Identification of chemical compounds that induce HIF-1alpha activity.

http://www.wikidata.org/entity/Q34023651

about

Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: focus on the cancer hallmark of tumor angiogenesis Paradigm shift in toxicity testing and modeling.Identification of small molecule compounds that inhibit the HIF-1 signaling pathway Identification of quaternary ammonium compounds as potent inhibitors of hERG potassium channels Chemical genomics profiling of environmental chemical modulation of human nuclear receptors.Systematic study of mitochondrial toxicity of environmental chemicals using quantitative high throughput screening.Application of a homogenous membrane potential assay to assess mitochondrial function.Profiling environmental chemicals for activity in the antioxidant response element signaling pathway using a high throughput screening approach.The future of toxicity testing: a focus on in vitro methods using a quantitative high-throughput screening platform.Bone morphogenetic protein-inducer tilorone identified by high-throughput screening is antifibrotic in vivo.Genome-wide analysis discloses reversal of the hypoxia-induced changes of gene expression in colon cancer cells by zinc supplementation.Quantitative high-throughput screening for chemical toxicity in a population-based in vitro model Using β-Lactamase and NanoLuc Luciferase Reporter Gene Assays to Identify Inhibitors of the HIF-1 Signaling Pathway.Identification of approved and investigational drugs that inhibit hypoxia-inducible factor-1 signaling.Improving the human hazard characterization of chemicals: a Tox21 update Deferoxamine Suppresses Collagen Cleavage and Protease, Cytokine, and COL10A1 Expression and Upregulates AMPK and Krebs Cycle Genes in Human Osteoarthritic Cartilage.The future of toxicity testing.An overview of transcriptional regulation in response to toxicological insult.Effect-based assessment of persistent organic pollutant and pesticide dumpsite using mammalian CALUX reporter cell lines.Methylseleninic acid downregulates hypoxia-inducible factor-1α in invasive prostate cancer.Prolyl-hydroxylase inhibitor activating hypoxia-inducible transcription factors reduce levels of transplant arteriosclerosis in a murine aortic allograft model.O-Phenanthroline as modulator of the hypoxic and catabolic response in cartilage tissue-engineering models.

P2860

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P2860

Identification of chemical compounds that induce HIF-1alpha activity.

http://www.wikidata.org/entity/Q34023651

description

2009 nî lūn-bûn

@nan

2009 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի հունիսին հրատարակված գիտական հոդված

@hy

2009年の論文

@ja

2009年論文

@yue

2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

@wuu

name

Identification of chemical compounds that induce HIF-1alpha activity.

@ast

Identification of chemical compounds that induce HIF-1alpha activity.

@en

Identification of chemical compounds that induce HIF-1alpha activity.

@nl

type

label

Identification of chemical compounds that induce HIF-1alpha activity.

@ast

Identification of chemical compounds that induce HIF-1alpha activity.

@en

Identification of chemical compounds that induce HIF-1alpha activity.

@nl

prefLabel

Identification of chemical compounds that induce HIF-1alpha activity.

@ast

Identification of chemical compounds that induce HIF-1alpha activity.

@en

Identification of chemical compounds that induce HIF-1alpha activity.

@nl

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Toxicological Sciences

P1476

Identification of chemical compounds that induce HIF-1alpha activity.

@en

P2093

James Inglese

http://www.w3.org/2001/XMLSchema#string

Kristine L Witt

http://www.w3.org/2001/XMLSchema#string

Menghang Xia

http://www.w3.org/2001/XMLSchema#string

Raymond R Tice

http://www.w3.org/2001/XMLSchema#string

Ruili Huang

http://www.w3.org/2001/XMLSchema#string

Shelley Force Aldred

http://www.w3.org/2001/XMLSchema#string

Yi Sun

http://www.w3.org/2001/XMLSchema#string

P2860

Role of hypoxia-inducible factor-1 in transcriptional activation of ceruloplasmin by iron deficiency

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1

Regulation of hypoxia-inducible factor 1alpha is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway

Targeting HIF-1 for cancer therapy

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

Asparagine hydroxylation of the HIF transactivation domain a hypoxic switch

HIF-1 alpha is required for solid tumor formation and embryonic vascularization.

Purification and characterization of hypoxia-inducible factor 1

Hypoxia-inducible factor 1alpha (HIF-1alpha) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes

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153-163

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scholarly article

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10.1093/TOXSCI/KFP123

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1

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112

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Gregg L. Semenza

Christopher P Austin

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2009-06-05T00:00:00Z

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26272552

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19502547

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2910898

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