A fusion of GMCSF and IL-21 initiates hypersignaling through the IL-21Ralpha chain with immune activating and tumoricidal effects in vivo

A fusion of GMCSF and IL-21 initiates hypersignaling through the IL-21Ralpha chain with immune activating and tumoricidal effects in vivo

Item
http://www.wikidata.org/entity/Q34025058
Maltose-binding protein fusion allows for high level bacterial expression and purification of bioactive mammalian cytokine derivativesA fusion cytokine coupling GMCSF to IL9 induces heterologous receptor clustering and STAT1 hyperactivation through JAK2 promiscuity.A MCP1 fusokine with CCR2-specific tumoricidal activityA GMCSF and IL7 fusion cytokine leads to functional thymic-dependent T-cell regeneration in age-associated immune deficiencyTherapeutic effects of bone marrow mesenchymal stem cells expressing interleukin-12 in mice bearing malignant ascites tumor.Reprogramming of B cells into regulatory cells with engineered fusokinesImmunotherapy for metastatic melanoma.Concise review: engineering the fusion of cytokines for the modulation of immune cellular responses in cancer and autoimmune disorders.Interleukin 21 - its potential role in the therapy of B-cell lymphomas.Engineered fusokine GIFT4 licenses the ability of B cells to trigger a tumoricidal T-cell response
P2860

A fusion of GMCSF and IL-21 initiates hypersignaling through the IL-21Ralpha chain with immune activating and tumoricidal effects in vivo

Item
http://www.wikidata.org/entity/Q34025058
description
2010 nî lūn-bûn
@nan
2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
A fusion of GMCSF and IL-21 in ...... nd tumoricidal effects in vivo
@ast
A fusion of GMCSF and IL-21 in ...... nd tumoricidal effects in vivo
@en
A fusion of GMCSF and IL-21 in ...... nd tumoricidal effects in vivo
@nl
type
label
A fusion of GMCSF and IL-21 in ...... nd tumoricidal effects in vivo
@ast
A fusion of GMCSF and IL-21 in ...... nd tumoricidal effects in vivo
@en
A fusion of GMCSF and IL-21 in ...... nd tumoricidal effects in vivo
@nl
prefLabel
A fusion of GMCSF and IL-21 in ...... nd tumoricidal effects in vivo
@ast
A fusion of GMCSF and IL-21 in ...... nd tumoricidal effects in vivo
@en
A fusion of GMCSF and IL-21 in ...... nd tumoricidal effects in vivo
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P577
P5875
P698
P932
P356
P1433
P1476
A fusion of GMCSF and IL-21 in ...... nd tumoricidal effects in vivo
@en
P2093
P2860
P304
P31
P356
P433
P478
P577
P5875
P698
P932