A common mutation in the 5,10-methylenetetrahydrofolate reductase gene affects genomic DNA methylation through an interaction with folate status. - Wikidata - awgldk - TriplyDB

A common mutation in the 5,10-methylenetetrahydrofolate reductase gene affects genomic DNA methylation through an interaction with folate status.

A common mutation in the 5,10-methylenetetrahydrofolate reductase gene affects genomic DNA methylation through an interaction with folate status.

http://www.wikidata.org/entity/Q34025724

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Mthfs is an Essential Gene in Mice and a Component of the Purinosome Methenyltetrahydrofolate synthetase regulates folate turnover and accumulation Neural tube defects and folate: case far from closed Diet and the epigenetic (re)programming of phenotypic differences in behavior Genome-wide association study of vitamin B6, vitamin B12, folate, and homocysteine blood concentrations Abnormal transmethylation/transsulfuration metabolism and DNA hypomethylation among parents of children with autism Polymorphisms of methylenetetrahydrofolate reductase (MTHFR) and susceptibility to pediatric acute lymphoblastic leukemia in a German study population.Biomarkers of Nutrition for Development-Folate Review The impact of nutrition on differential methylated regions of the genome Folate and DNA methylation: a review of molecular mechanisms and the evidence for folate's role Detection of metabolic syndrome in schizophrenia and implications for antipsychotic therapy : is there a role for folate?Modeling cellular compartmentation in one-carbon metabolism In utero alcohol exposure, epigenetic changes, and their consequences Folate and asthma.Epigenetic modifications: basic mechanisms and role in cardiovascular disease.Novel Approaches to Investigate One-Carbon Metabolism and Related B-Vitamins in Blood Pressure Hyperhomocysteinemia and mortality after coronary artery bypass grafting Methotrexate-induced decrease in embryonic 5-methyl-tetrahydrofolate is irreversible with leucovorin supplementation Folate deficiency alters hepatic and colon MGMT and OGG-1 DNA repair protein expression in rats but has no effect on genome-wide DNA methylation Mutation in folate metabolism causes epigenetic instability and transgenerational effects on development A genetic signature of spina bifida risk from pathway-informed comprehensive gene-variant analysis A hypomethylating variant of MTHFR, 677C>T, blunts the neural response to errors in patients with schizophrenia and healthy individuals No effect of folic acid supplementation on global DNA methylation in men and women with moderately elevated homocysteine Animal models of gene-environment interaction in schizophrenia: A dimensional perspective.Folate during reproduction: the Canadian experience with folic acid fortification.Integrated approach of nutritional and molecular epidemiology, mineralogical and chemical pollutant characterisation: the protocol of a cross-sectional study in women Genetic variability in the MTHFR gene and colorectal cancer risk using the colorectal cancer family registry.Mechanistic insights into folate supplementation from Crooked tail and other NTD-prone mutant mice.Influence of MTHFR Genetic Background on p16 and MGMT Methylation in Oral Squamous Cell Cancer MTHFR C677T and postmenopausal breast cancer risk by intakes of one-carbon metabolism nutrients: a nested case-control study.Genetic control of individual differences in gene-specific methylation in human brain.Impact of folic acid fortification on global DNA methylation and one-carbon biomarkers in the Women's Health Initiative Observational Study cohort Choline intake exceeding current dietary recommendations preserves markers of cellular methylation in a genetic subgroup of folate-compromised men.Epigenetic genes and emotional reactivity to daily life events: a multi-step gene-environment interaction study.Diet folate, DNA methylation and genetic polymorphisms of MTHFR C677T in association with the prognosis of esophageal squamous cell carcinoma Azoxymethane-induced colon carcinogenesis in mice occurs independently of de novo thymidylate synthesis capacity.Increasing maternal or post-weaning folic acid alters gene expression and moderately changes behavior in the offspring Dissociable genetic contributions to error processing: a multimodal neuroimaging study.Maternal MTHFR genotype and haplotype predict deficits in early cognitive development in a lead-exposed birth cohort in Mexico City Opposing effects of DNA hypomethylation on intestinal and liver carcinogenesis

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P2860

A common mutation in the 5,10-methylenetetrahydrofolate reductase gene affects genomic DNA methylation through an interaction with folate status.

http://www.wikidata.org/entity/Q34025724

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2002 nî lūn-bûn

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2002 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2002 թվականի ապրիլին հրատարակված գիտական հոդված

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2002年の論文

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2002年論文

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2002年論文

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2002年論文

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A common mutation in the 5,10- ...... nteraction with folate status.

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A common mutation in the 5,10- ...... nteraction with folate status.

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Proceedings of the National Academy of Sciences of the United States of America

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A common mutation in the 5,10- ...... interaction with folate status

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P2093

Domenico Girelli

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Irwin H Rosenberg

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Jacob Selhub

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Joel B Mason

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Paul F Jacques

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Roberto Corrocher

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Sang-Woon Choi

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Simonetta Friso

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P2860

DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development

Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex

A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase

Polymorphisms in the methylenetetrahydrofolate reductase gene are associated with susceptibility to acute leukemia in adults

The structure and properties of methylenetetrahydrofolate reductase from Escherichia coli suggest how folate ameliorates human hyperhomocysteinemia

CpG-rich islands and the function of DNA methylation

DNA methylation and gene function

A common mutation in the methylenetetrahydrofolate reductase gene is associated with an accumulation of formylated tetrahydrofolates in red blood cells

Electrospray ionization mass spectrometry of 5-methyl-2'-deoxycytidine and its determination in urine by liquid chromatography/electrospray ionization tandem mass spectrometry

Exon-specific DNA hypomethylation of the p53 gene of rat colon induced by dimethylhydrazine. Modulation by dietary folate

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5606-5611

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10.1073/PNAS.062066299

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8

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99

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Gregory Dolnikowski

Oliviero Olivieri

Pamela J Bagley

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2002-04-02T00:00:00Z

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11435479

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11929966

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DNA methylation

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122817

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