Three-dimensional structures of soluble CD4-bound states of trimeric simian immunodeficiency virus envelope glycoproteins determined by using cryo-electron tomography
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Structural mechanism of trimeric HIV-1 envelope glycoprotein activationHIV-1 envelope glycoprotein structureRecent advances on the use of structural biology for the design of novel envelope immunogens of HIV-1HIV-1 variable loop 2 and its importance in HIV-1 infection and vaccine developmentMutations in HIV-1 envelope that enhance entry with the macaque CD4 receptor alter antibody recognition by disrupting quaternary interactions within the trimer.Controlling the HIV/AIDS epidemic: current status and global challengesAntigenic and 3D structural characterization of soluble X4 and hybrid X4-R5 HIV-1 Env trimersVisualization of retroviral envelope spikes in complex with the V3 loop antibody 447-52D on intact viruses by cryo-electron tomography.A collaborative framework for 3D alignment and classification of heterogeneous subvolumes in cryo-electron tomography.Cryo-electron microscopy--a primer for the non-microscopist.Molecular structures of trimeric HIV-1 Env in complex with small antibody derivatives.HIV-2 interaction with cell coreceptors: amino acids within the V1/V2 region of viral envelope are determinant for CCR8, CCR5 and CXCR4 usage.Epitope mapping of M36, a human antibody domain with potent and broad HIV-1 inhibitory activity.Comprehensive antigenic map of a cleaved soluble HIV-1 envelope trimer.Griffithsin tandemers: flexible and potent lectin inhibitors of the human immunodeficiency virusWhole-body immunoPET reveals active SIV dynamics in viremic and antiretroviral therapy-treated macaques.Characterization and Implementation of a Diverse Simian Immunodeficiency Virus SIVsm Envelope Panel in the Assessment of Neutralizing Antibody Breadth Elicited in Rhesus Macaques by Multimodal Vaccines Expressing the SIVmac239 Envelope.Broadly Neutralizing Antibody 8ANC195 Recognizes Closed and Open States of HIV-1 Env.Morphology and ultrastructure of retrovirus particles.Lineage-specific differences between human and simian immunodeficiency virus regulation of gp120 trimer association and CD4 bindingAcquisition of CD4-dependence by CD4-independent SIV passaged in human peripheral blood mononuclear cellsReceptor Activation of HIV-1 Env Leads to Asymmetric Exposure of the gp41 Trimer.Derivation and Characterization of a CD4-Independent, Non-CD4-Tropic Simian Immunodeficiency Virus.HIV-1 envelope glycoprotein trimers display open quaternary conformation when bound to the gp41 membrane-proximal external-region-directed broadly neutralizing antibody Z13e1CD4+ T cells support production of simian immunodeficiency virus Env antibodies that enforce CD4-dependent entry and shape tropism in vivo.Limiting factors in single particle cryo electron tomography.Structural insights into key sites of vulnerability on HIV-1 Env and influenza HA.Loss of a conserved N-linked glycosylation site in the simian immunodeficiency virus envelope glycoprotein V2 region enhances macrophage tropism by increasing CD4-independent cell-to-cell transmission.Efficiency of bridging-sheet recruitment explains HIV-1 R5 envelope glycoprotein sensitivity to soluble CD4 and macrophage tropism.Unraveling the structural basis of HIV-1 neutralization.Structure of Simian Immunodeficiency Virus Envelope Spikes Bound with CD4 and Monoclonal Antibody 36D5.Functional insights into pathogen biology from 3D electron microscopy.Trimeric HIV Env provides epitope occlusion mediated by hypervariable loopsTruncating the Gp41 Cytoplasmic Tail of SIV Decreases Sensitivity to Neutralizing Antibodies without Increasing Envelope Content of Virions.Comparison of Uncleaved and Mature Human Immunodeficiency Virus (HIV-1) Membrane Envelope Glycoprotein Trimers.
P2860
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P2860
Three-dimensional structures of soluble CD4-bound states of trimeric simian immunodeficiency virus envelope glycoproteins determined by using cryo-electron tomography
description
2011 nî lūn-bûn
@nan
2011 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Three-dimensional structures o ...... using cryo-electron tomography
@ast
Three-dimensional structures o ...... using cryo-electron tomography
@en
Three-dimensional structures o ...... using cryo-electron tomography
@nl
type
label
Three-dimensional structures o ...... using cryo-electron tomography
@ast
Three-dimensional structures o ...... using cryo-electron tomography
@en
Three-dimensional structures o ...... using cryo-electron tomography
@nl
prefLabel
Three-dimensional structures o ...... using cryo-electron tomography
@ast
Three-dimensional structures o ...... using cryo-electron tomography
@en
Three-dimensional structures o ...... using cryo-electron tomography
@nl
P2093
P2860
P50
P356
P1433
P1476
Three-dimensional structures o ...... using cryo-electron tomography
@en
P2093
Alberto Bartesaghi
Jacqueline L S Milne
James A Hoxie
Jeffrey D Lifson
Julian W Bess
Mario J Borgnia
Rachna Nandwani
P2860
P304
12114-12123
P356
10.1128/JVI.05297-11
P407
P577
2011-09-21T00:00:00Z