Obesity affects the chondrocyte responsiveness to leptin in patients with osteoarthritis - Wikidata - awgldk - TriplyDB

Obesity affects the chondrocyte responsiveness to leptin in patients with osteoarthritis

Obesity affects the chondrocyte responsiveness to leptin in patients with osteoarthritis

http://www.wikidata.org/entity/Q34027592

about

A Tale of Two Joints: The Role of Matrix Metalloproteases in Cartilage Biology Leptin - a link between obesity and osteoarthritis. applications for prevention and treatment Obesity & osteoarthritis Pathobiology of obesity and osteoarthritis: integrating biomechanics and inflammation.Fibroblast-growth factor 23 promotes terminal differentiation of ATDC5 cells.The effects of adipokines on cartilage and meniscus catabolism The role of leptin on the organization and expression of cytoskeleton elements in nucleus pulposus cells.Catabolic and proinflammatory effects of leptin in chondrocytes are regulated by suppressor of cytokine signaling-3 Leptin activates RhoA/ROCK pathway to induce cytoskeleton remodeling in nucleus pulposus cells.Surmounting chemotherapy and radioresistance in chondrosarcoma: molecular mechanisms and therapeutic targets.What's new in our understanding of the role of adipokines in rheumatic diseases?High-fat diet-induced acceleration of osteoarthritis is associated with a distinct and sustained plasma metabolite signature.Correlations between serum adipocytokine concentrations, disease stage, radiological status and total body fat content in the patients with primary knee osteoarthritis.Serum adipokines, adipose tissue measurements and metabolic parameters in patients with advanced radiographic knee osteoarthritis.Effects of Adipokines and Insulin on Intracellular pH, Calcium Concentration, and Responses to Hypo-Osmolarity in Human Articular Chondrocytes from Healthy and Osteoarthritic Cartilage.The association of adipokine levels in plasma and synovial fluid with the severity of knee osteoarthritis.Association between the chondrocyte phenotype and the expression of adipokines and their receptors: evidence for a role of leptin but not adiponectin in the expression of cartilage-specific markers.Obesity-related adipokines predict patient-reported shoulder pain.LncRNA-UCA1 enhances MMP-13 expression by inhibiting miR-204-5p in human chondrocytes.Leptin alone and in combination with interleukin-1-beta induced cartilage degradation potentially inhibited by EPA and DHA.Adipokines and inflammation: is it a question of weight?Osteoarthritis-Like Changes in Bardet-Biedl Syndrome Mutant Ciliopathy Mice (Bbs1M390R/M390R): Evidence for a Role of Primary Cilia in Cartilage Homeostasis and Regulation of Inflammation.

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Obesity affects the chondrocyte responsiveness to leptin in patients with osteoarthritis

http://www.wikidata.org/entity/Q34027592

description

2010 nî lūn-bûn

@nan

2010 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հունիսին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

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2010年論文

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2010年论文

@wuu

name

Obesity affects the chondrocyte responsiveness to leptin in patients with osteoarthritis

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Obesity affects the chondrocyte responsiveness to leptin in patients with osteoarthritis

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Obesity affects the chondrocyte responsiveness to leptin in patients with osteoarthritis

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type

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Obesity affects the chondrocyte responsiveness to leptin in patients with osteoarthritis

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Obesity affects the chondrocyte responsiveness to leptin in patients with osteoarthritis

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Obesity affects the chondrocyte responsiveness to leptin in patients with osteoarthritis

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prefLabel

Obesity affects the chondrocyte responsiveness to leptin in patients with osteoarthritis

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Obesity affects the chondrocyte responsiveness to leptin in patients with osteoarthritis

@en

Obesity affects the chondrocyte responsiveness to leptin in patients with osteoarthritis

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Arthritis Research and Therapy

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Obesity affects the chondrocyte responsiveness to leptin in patients with osteoarthritis

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Bernard Terlain

http://www.w3.org/2001/XMLSchema#string

Cécile Guillaume

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Didier Mainard

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Nathalie Presle

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Pascale Gegout-Pottie

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Patrick Netter

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Pierre-Jean Francin

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Stéphane Pallu

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P2860

Obesity and osteoarthritis: more complex than predicted!

Signalling pathway involved in nitric oxide synthase type II activation in chondrocytes: synergistic effect of leptin with interleukin-1

Leptin enhances synthesis of proinflammatory mediators in human osteoarthritic cartilage--mediator role of NO in leptin-induced PGE2, IL-6, and IL-8 production

Extreme obesity due to impaired leptin signaling in mice does not cause knee osteoarthritis.

Mechanisms of leptin action and leptin resistance.

Epigenetic regulation of leptin affects MMP-13 expression in osteoarthritic chondrocytes: possible molecular target for osteoarthritis therapeutic intervention.

Intracellular signalling pathways activated by leptin.

Relationship between body adiposity measures and risk of primary knee and hip replacement for osteoarthritis: a prospective cohort study.

Human articular chondrocytes express functional leptin receptors.

Differential expression of leptin and leptin's receptor isoform (Ob-Rb) mRNA between advanced and minimally affected osteoarthritic cartilage; effect on cartilage metabolism.

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scholarly article

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10.1186/AR3048

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3

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12

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2010-06-09T00:00:00Z

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1001092041

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20534145

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2911905

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