Generation of functional antigen-specific T cells in defined genetic backgrounds by retrovirus-mediated expression of TCR cDNAs in hematopoietic precursor cells.
about
Tumor immunotherapy across MHC barriers using allogeneic T-cell precursorsEngineering antigen-specific T cells from genetically modified human hematopoietic stem cells in immunodeficient mice.Adoptive transfer of MART-1 T-cell receptor transgenic lymphocytes and dendritic cell vaccination in patients with metastatic melanomaLong-term in vivo provision of antigen-specific T cell immunity by programming hematopoietic stem cells.Transplantation of mouse HSCs genetically modified to express a CD4-restricted TCR results in long-term immunity that destroys tumors and initiates spontaneous autoimmunityStem cell-based anti-HIV gene therapy.Targeting tumours with genetically enhanced T lymphocytes.Prospects for immunotherapy of malignant disease.Genetic engineering of hematopoietic stem cells to generate invariant natural killer T cellsInteractions between IL-32 and tumor necrosis factor alpha contribute to the exacerbation of immune-inflammatory diseases.Antitumor activity from antigen-specific CD8 T cells generated in vivo from genetically engineered human hematopoietic stem cells.Therapeutic potential of a tumor-specific, MHC-unrestricted T-cell receptor expressed on effector cells of the innate and the adaptive immune system through bone marrow transduction and immune reconstitution.Supernatural T cells: genetic modification of T cells for cancer therapy.Introduction of exogenous T-cell receptors into human hematopoietic progenitors results in exclusion of endogenous T-cell receptor expression.T-cell receptor gene therapy for cancer: the progress to date and future objectives.Gamma-retroviral vectors enveloped with an antibody and an engineered fusogenic protein achieved antigen-specific targeting.Enhancing T cell reconstitution after hematopoietic stem cell transplantation: a brief update of the latest trendsRetrogenic modeling of experimental allergic encephalomyelitis associates T cell frequency but not TCR functional affinity with pathogenicityIn vitro differentiation of adult bone marrow progenitors into antigen-specific CD4 helper T cells using engineered stromal cells expressing a notch ligand and a major histocompatibility complex class II protein.Subtle affinity-enhancing mutations in a myelin oligodendrocyte glycoprotein-specific TCR alter specificity and generate new self-reactivity.IL-13Rα1 is a surface marker for M2 macrophages influencing their differentiation and function.T-cell receptor retrogenic mice: a rapid, flexible alternative to T-cell receptor transgenic mice.Precursor B cell receptor signaling activity can be uncoupled from surface expression.Human melanoma immunotherapy using tumor antigen-specific T cells generated in humanized mice.Characterization of Postinfusion Phenotypic Differences in Fresh Versus Cryopreserved TCR Engineered Adoptive Cell Therapy Products.Lentiviral calnexin-modified dendritic cells promote expansion of high-avidity effector T cells with central memory phenotype.
P2860
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P2860
Generation of functional antigen-specific T cells in defined genetic backgrounds by retrovirus-mediated expression of TCR cDNAs in hematopoietic precursor cells.
description
2002 nî lūn-bûn
@nan
2002 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Generation of functional antig ...... hematopoietic precursor cells.
@ast
Generation of functional antig ...... hematopoietic precursor cells.
@en
Generation of functional antig ...... hematopoietic precursor cells.
@nl
type
label
Generation of functional antig ...... hematopoietic precursor cells.
@ast
Generation of functional antig ...... hematopoietic precursor cells.
@en
Generation of functional antig ...... hematopoietic precursor cells.
@nl
prefLabel
Generation of functional antig ...... hematopoietic precursor cells.
@ast
Generation of functional antig ...... hematopoietic precursor cells.
@en
Generation of functional antig ...... hematopoietic precursor cells.
@nl
P2093
P2860
P356
P1476
Generation of functional antig ...... hematopoietic precursor cells.
@en
P2093
David Baltimore
Luk Van Parijs
Xiao-Feng Qin
P2860
P304
P356
10.1073/PNAS.092154599
P407
P577
2002-04-01T00:00:00Z