Surface IgM stimulation induces MEK1/2-dependent MYC expression in chronic lymphocytic leukemia cells.
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The outcome of B-cell receptor signaling in chronic lymphocytic leukemia: proliferation or anergyThe role of the JAK-STAT pathway and related signal cascades in telomerase activation during the development of hematologic malignanciesLoss of thyroid hormone receptor interactor 13 inhibits cell proliferation and survival in human chronic lymphocytic leukemiaStimulation of the B-cell receptor activates the JAK2/STAT3 signaling pathway in chronic lymphocytic leukemia cells.Stimulation of surface IgM of chronic lymphocytic leukemia cells induces an unfolded protein response dependent on BTK and SYK.A combination of cytokines rescues highly purified leukemic CLL B-cells from spontaneous apoptosis in vitro.CLL cells respond to B-Cell receptor stimulation with a microRNA/mRNA signature associated with MYC activation and cell cycle progressionExcessive antigen reactivity may underlie the clinical aggressiveness of chronic lymphocytic leukemia stereotyped subset #8.TLR-9 and IL-15 Synergy Promotes the In Vitro Clonal Expansion of Chronic Lymphocytic Leukemia B Cells.miR-125b Is an adhesion-regulated microRNA that protects mesenchymal stem cells from anoikis.The B-cell receptor signaling pathway as a therapeutic target in CLL.T-cell number and subtype influence the disease course of primary chronic lymphocytic leukaemia xenografts in alymphoid mice.Novel Agents and Emerging Strategies for Targeting the B-Cell Receptor Pathway in CLLMimicking the tumour microenvironment of chronic lymphocytic leukaemia in vitro critically depends on the type of B-cell receptor stimulation.Biology of chronic lymphocytic leukemia in different microenvironments: clinical and therapeutic implications.Association between B-cell receptor responsiveness and disease progression in B-cell chronic lymphocytic leukemia: results from single cell network profiling studies.Bruton's tyrosine kinase (BTK) function is important to the development and expansion of chronic lymphocytic leukemia (CLL).PEITC-mediated inhibition of mRNA translation is associated with both inhibition of mTORC1 and increased eIF2α phosphorylation in established cell lines and primary human leukemia cells.Signaling pathways activated by the B-cell receptor in chronic lymphocytic leukemia.Coming full circle: 70 years of chronic lymphocytic leukemia cell redistribution, from glucocorticoids to inhibitors of B-cell receptor signalingB-cell antigen receptor signaling in chronic lymphocytic leukemia: therapeutic targets and translational opportunities.Microenvironment interactions and B-cell receptor signaling in Chronic Lymphocytic Leukemia: Implications for disease pathogenesis and treatment.Modulation of B-cell receptor and microenvironment signaling by a guanine exchange factor in B-cell malignanciesThe Role of c-MYC in B-Cell Lymphomas: Diagnostic and Molecular AspectsCombination of the MEK inhibitor pimasertib with BTK or PI3K-delta inhibitors is active in preclinical models of aggressive lymphomas.Functional Differences between IgM and IgD Signaling in Chronic Lymphocytic LeukemiaInhibition of BCR signaling using the Syk inhibitor TAK-659 prevents stroma-mediated signaling in chronic lymphocytic leukemia cells.Integration of B-cell receptor-induced ERK1/2 phosphorylation and mutations of SF3B1 gene refines prognosis in treatment-naïve chronic lymphocytic leukemiaMYC addiction in chronic lymphocytic leukemia.Extracellular vesicles of bone marrow stromal cells rescue chronic lymphocytic leukemia B cells from apoptosis, enhance their migration and induce gene expression modifications.A B Cell Regulome Links Notch to Downstream Oncogenic Pathways in Small B Cell Lymphomas.Amplification of B cell receptor-Erk signaling by Rasgrf-1 overexpression in chronic lymphocytic leukemia.
P2860
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P2860
Surface IgM stimulation induces MEK1/2-dependent MYC expression in chronic lymphocytic leukemia cells.
description
2011 nî lūn-bûn
@nan
2011 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Surface IgM stimulation induce ...... ic lymphocytic leukemia cells.
@ast
Surface IgM stimulation induce ...... ic lymphocytic leukemia cells.
@en
Surface IgM stimulation induce ...... ic lymphocytic leukemia cells.
@nl
type
label
Surface IgM stimulation induce ...... ic lymphocytic leukemia cells.
@ast
Surface IgM stimulation induce ...... ic lymphocytic leukemia cells.
@en
Surface IgM stimulation induce ...... ic lymphocytic leukemia cells.
@nl
prefLabel
Surface IgM stimulation induce ...... ic lymphocytic leukemia cells.
@ast
Surface IgM stimulation induce ...... ic lymphocytic leukemia cells.
@en
Surface IgM stimulation induce ...... ic lymphocytic leukemia cells.
@nl
P2093
P1433
P1476
Surface IgM stimulation induce ...... nic lymphocytic leukemia cells
@en
P2093
Alex Paterson
C Ian Mockridge
Kathleen N Potter
Kelly-Ann Smith
Margaret Ashton-Key
Samantha Dias
Sergey Krysov
P304
P356
10.1182/BLOOD-2011-07-370403
P407
P577
2011-11-15T00:00:00Z