Loss of the Drosophila cell polarity regulator Scribbled promotes epithelial tissue overgrowth and cooperation with oncogenic Ras-Raf through impaired Hippo pathway signaling - Wikidata - awgldk - TriplyDB

Loss of the Drosophila cell polarity regulator Scribbled promotes epithelial tissue overgrowth and cooperation with oncogenic Ras-Raf through impaired Hippo pathway signaling

Loss of the Drosophila cell polarity regulator Scribbled promotes epithelial tissue overgrowth and cooperation with oncogenic Ras-Raf through impaired Hippo pathway signaling

http://www.wikidata.org/entity/Q34034164

about

Interaction proteome of human Hippo signaling: modular control of the co-activator YAP1 Cell competition: how to eliminate your neighbours The BTB-zinc finger transcription factor abrupt acts as an epithelial oncogene in Drosophila melanogaster through maintaining a progenitor-like cell state The F-box protein Slmb restricts the activity of aPKC to polarize epithelial cells Drosophila Myc: A master regulator of cellular performance.Impaired Hippo signaling promotes Rho1-JNK-dependent growth.Differential regulation of the Hippo pathway by adherens junctions and apical-basal cell polarity modules Discovery of transcription factors and regulatory regions driving in vivo tumor development by ATAC-seq and FAIRE-seq open chromatin profiling.Tumor suppression by cell competition through regulation of the Hippo pathway.BTB-Zinc Finger Oncogenes Are Required for Ras and Notch-Driven Tumorigenesis in Drosophila.Cooperation of the BTB-Zinc finger protein, Abrupt, with cytoskeletal regulators in Drosophila epithelial tumorigenesis.Loss of Cell Adhesion Increases Tumorigenic Potential of Polarity Deficient Scribble Mutant Cells Regulation of Notch signaling and endocytosis by the Lgl neoplastic tumor suppressor.MYC, Cell Competition, and Cell Death in Cancer: The Inseparable Triad.Src controls tumorigenesis via JNK-dependent regulation of the Hippo pathway in Drosophila.Mechanisms of cell competition: themes and variations.In Drosophila, RhoGEF2 cooperates with activated Ras in tumorigenesis through a pathway involving Rho1-Rok-Myosin-II and JNK signalling RAF kinase inhibitor-independent constitutive activation of Yes-associated protein 1 promotes tumor progression in thyroid cancer AJUBA LIM Proteins Limit Hippo Activity in Proliferating Cells by Sequestering the Hippo Core Kinase Complex in the Cytosol.Rabaptin-5 and Rabex-5 are neoplastic tumour suppressor genes that interact to modulate Rab5 dynamics in Drosophila melanogaster.Fold formation at the compartment boundary of Drosophila wing requires Yki signaling to suppress JNK dependent apoptosis.Bendless modulates JNK-mediated cell death and migration in Drosophila.Dissecting social cell biology and tumors using Drosophila genetics.Causes and consequences of genetic background effects illuminated by integrative genomic analysis.New frontiers in cell competition.The Scribble-Dlg-Lgl polarity module in development and cancer: from flies to man.Hippo gains weight: added insights and complexity to pathway control.Hippo-YAP signaling pathway: A new paradigm for cancer therapy.Cell competition in vertebrate organ size regulation.Integrin signalling regulates YAP and TAZ to control skin homeostasis.A Kinome RNAi Screen in Drosophila Identifies Novel Genes Interacting with Lgl, aPKC, and Crb Cell Polarity Genes in Epithelial Tissues.Scribble acts in the Drosophila fat-hippo pathway to regulate warts activity.The transcriptional response to tumorigenic polarity loss in Drosophila.Autophagy suppresses Ras-driven epithelial tumourigenesis by limiting the accumulation of reactive oxygen species.A non-cell-autonomous tumor suppressor role for Stat in eliminating oncogenic scribble cells.Selection for long and short sleep duration in Drosophila melanogaster reveals the complex genetic network underlying natural variation in sleep.Feedback amplification loop drives malignant growth in epithelial tissues.Drosophila melanogaster Guk-holder interacts with the Scribbled PDZ1 domain and regulates epithelial development with Scribbled and Discs Large.POSH regulates Hippo signaling through ubiquitin-mediated expanded degradation.Differential roles of the Drosophila EMT-inducing transcription factors Snail and Serpent in driving primary tumour growth.

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Loss of the Drosophila cell polarity regulator Scribbled promotes epithelial tissue overgrowth and cooperation with oncogenic Ras-Raf through impaired Hippo pathway signaling

http://www.wikidata.org/entity/Q34034164

description

2011 nî lūn-bûn

@nan

2011 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

Loss of the Drosophila cell po ...... paired Hippo pathway signaling

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Loss of the Drosophila cell po ...... paired Hippo pathway signaling

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Loss of the Drosophila cell po ...... paired Hippo pathway signaling

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type

label

Loss of the Drosophila cell po ...... paired Hippo pathway signaling

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Loss of the Drosophila cell po ...... paired Hippo pathway signaling

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Loss of the Drosophila cell po ...... paired Hippo pathway signaling

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prefLabel

Loss of the Drosophila cell po ...... paired Hippo pathway signaling

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Loss of the Drosophila cell po ...... paired Hippo pathway signaling

@en

Loss of the Drosophila cell po ...... paired Hippo pathway signaling

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1471-213X-11-57

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BMC Developmental Biology

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Loss of the Drosophila cell po ...... paired Hippo pathway signaling

@en

P2093

Anthony M Brumby

http://www.w3.org/2001/XMLSchema#string

Felix A Grusche

http://www.w3.org/2001/XMLSchema#string

Karen Doggett

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P2860

Molecular interactions between Vestigial and Scalloped promote wing formation in Drosophila

Deregulation of scribble promotes mammary tumorigenesis and reveals a role for cell polarity in carcinoma

Linking cell cycle to asymmetric division: Aurora-A phosphorylates the Par complex to regulate Numb localization

salvador Promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines

Actin-Capping Protein and the Hippo pathway regulate F-actin and tissue growth in Drosophila

The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP

SCALLOPED interacts with YORKIE, the nuclear effector of the hippo tumor-suppressor pathway in Drosophila

Loss of human Scribble cooperates with H-Ras to promote cell invasion through deregulation of MAPK signalling

Identifying tumor suppressors in genetic mosaics: the Drosophila lats gene encodes a putative protein kinase

Identification of Vangl2 and Scrb1 as planar polarity genes in mammals

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1471-213x-11-57

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57

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scholarly article

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10.1186/1471-213X-11-57

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11

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Helena E. Richardson

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2011-09-29T00:00:00Z

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1034262168

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21955824

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3206446

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