Protection against filovirus diseases by a novel broad-spectrum nucleoside analogue BCX4430. - Wikidata - awgldk - TriplyDB

Protection against filovirus diseases by a novel broad-spectrum nucleoside analogue BCX4430.

Protection against filovirus diseases by a novel broad-spectrum nucleoside analogue BCX4430.

http://www.wikidata.org/entity/Q34040052

about

Membrane binding and bending in Ebola VP40 assembly and egress Outbreaks of Ebola virus disease in Africa: the beginnings of a tragic saga Ebola virus disease Development of Medical Countermeasures to Middle East Respiratory Syndrome Coronavirus Ebola Hemorrhagic Fever as a Public Health Emergency of International Concern; a Review Article Filoviruses: One of These Things is (not) Like the Other Addressing Therapeutic Options for Ebola Virus Infection in Current and Future Outbreaks Pre-symptomatic diagnosis and treatment of filovirus diseases Neglected filoviruses Clomiphene and Its Isomers Block Ebola Virus Particle Entry and Infection with Similar Potency: Potential Therapeutic Implications Molecular Basis for the Selective Inhibition of Respiratory Syncytial Virus RNA Polymerase by 2'-Fluoro-4'-Chloromethyl-Cytidine Triphosphate Immucillins ImmA and ImmH Are Effective and Non-toxic in the Treatment of Experimental Visceral Leishmaniasis A Rapid Screening Assay Identifies Monotherapy with Interferon-ß and Combination Therapies with Nucleoside Analogs as Effective Inhibitors of Ebola Virus Broad-spectrum agents for flaviviral infections: dengue, Zika and beyond Updates in diagnosis and management of Ebola hemorrhagic fever.Ebola virus: A gap in drug design and discovery - experimental and computational perspective.Ebola virus - from neglected threat to global emergency state.Ebola Virus Infection: Review of the Pharmacokinetic and Pharmacodynamic Properties of Drugs Considered for Testing in Human Efficacy Trials.Anti-Ebola therapies based on monoclonal antibodies: current state and challenges ahead.The phosphatidylinositol-3-phosphate 5-kinase inhibitor apilimod blocks filoviral entry and infection Potential clinical treatment for Ebola pandemic.Flavonoids as multi-target inhibitors for proteins associated with Ebola virus: in-silico discovery using virtual screening and molecular docking studies.The multifunctional Ebola virus VP40 matrix protein is a promising therapeutic target.Flavonoids as Multi-target Inhibitors for Proteins Associated with Ebola Virus: In Silico Discovery Using Virtual Screening and Molecular Docking Studies.Efficacy of the broad-spectrum antiviral compound BCX4430 against Zika virus in cell culture and in a mouse model.THE STRENGTHS, WEAKNESSES, OPPORTUNITIES, AND THREATS (SWOTs) ANALYSES OF THE EBOLA VIRUS - PAPER RETRACTED.Hemorrhagic fever of bunyavirus etiology: disease models and progress towards new therapies.Possible leap ahead in filovirus therapeutics.High dose sertraline monotherapy fails to protect rhesus macaques from lethal challenge with Ebola virus Makona.BCX4430, a novel nucleoside analog, effectively treats yellow fever in a Hamster model Synthetic antibodies with a human framework that protect mice from lethal Sudan ebolavirus challenge Treatment of ebola virus disease.Human Ebola virus infection in West Africa: a review of available therapeutic agents that target different steps of the life cycle of Ebola virus.Small molecules with antiviral activity against the Ebola virus Therapeutic efficacy of the small molecule GS-5734 against Ebola virus in rhesus monkeys.A Randomized, Controlled Trial of ZMapp for Ebola Virus Infection Structures of protective antibodies reveal sites of vulnerability on Ebola virus.Humanitarian access to unapproved interventions in public health emergencies of international concern.Mechanism of human antibody-mediated neutralization of Marburg virus High-content image-based screening of a signal transduction pathway inhibitor small-molecule library against highly pathogenic RNA viruses.

P2860

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P2860

Protection against filovirus diseases by a novel broad-spectrum nucleoside analogue BCX4430.

http://www.wikidata.org/entity/Q34040052

description

2014 nî lūn-bûn

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2014 թուականի Մարտին հրատարակուած գիտական յօդուած

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2014 թվականի մարտին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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Protection against filovirus d ...... m nucleoside analogue BCX4430.

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Protection against filovirus d ...... m nucleoside analogue BCX4430.

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Protection against filovirus d ...... m nucleoside analogue BCX4430.

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Protection against filovirus d ...... m nucleoside analogue BCX4430.

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Protection against filovirus d ...... m nucleoside analogue BCX4430.

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Protection against filovirus d ...... m nucleoside analogue BCX4430.

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Protection against filovirus d ...... m nucleoside analogue BCX4430.

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Protection against filovirus d ...... m nucleoside analogue BCX4430.

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Protection against filovirus d ...... m nucleoside analogue BCX4430.

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P2093

Brett P Eaton

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Brian R Taubenheim

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Cary J Retterer

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Dena M Minning

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Jay Wells

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Kelly S Stuthman

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Lian Dong

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Lisa S Welch

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Nicole L Garza

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Pravin Kotian

http://www.w3.org/2001/XMLSchema#string

P2860

Newly discovered ebola virus associated with hemorrhagic fever outbreak in Uganda

Development of a preventive vaccine for Ebola virus infection in primates

Prospects for treatment of viral hemorrhagic fevers with ribavirin, a broad-spectrum antiviral drug

Development and characterization of a mouse model for Marburg hemorrhagic fever

Antiviral activity of a small-molecule inhibitor of filovirus infection

3-deazaneplanocin A induces massively increased interferon-alpha production in Ebola virus-infected mice.

Assessment of the risk of Ebola virus transmission from bodily fluids and fomites.

Postexposure protection of non-human primates against a lethal Ebola virus challenge with RNA interference: a proof-of-concept study.

Marburg-virus disease in Kenya.

Identification of an antioxidant small-molecule with broad-spectrum antiviral activity.

P2888

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402-405

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10.1038/NATURE13027

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7496

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508

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Gianluca Pegoraro

Rekha G Panchal

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2014-03-02T00:00:00Z

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1027597733

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7095208

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