Fisetin induces autophagic cell death through suppression of mTOR signaling pathway in prostate cancer cells. - Wikidata - awgldk - TriplyDB

Fisetin induces autophagic cell death through suppression of mTOR signaling pathway in prostate cancer cells.

Fisetin induces autophagic cell death through suppression of mTOR signaling pathway in prostate cancer cells.

http://www.wikidata.org/entity/Q34042356

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mTOR/p70S6K signaling distinguishes routine, maintenance-level autophagy from autophagic cell death during influenza A infection Inhibition of Akt/mTOR signaling by the dietary flavonoid fisetin Fisetin: a dietary antioxidant for health promotion Anti-androgenic effects of flavonols in prostate cancer Autophagy and cancer Dietary flavonoid fisetin: a novel dual inhibitor of PI3K/Akt and mTOR for prostate cancer management Insights into the inhibition of the p90 ribosomal S6 kinase (RSK) by the flavonol glycoside SL0101 from the 1.5 Å crystal structure of the N-terminal domain of RSK2 with bound inhibitor.Identification of quercitrin as an inhibitor of the p90 S6 ribosomal kinase (RSK): structure of its complex with the N-terminal domain of RSK2 at 1.8 Å resolution Dietary polyphenols in prevention and treatment of prostate cancer Fisetin inhibits migration and invasion of human cervical cancer cells by down-regulating urokinase plasminogen activator expression through suppressing the p38 MAPK-dependent NF-κB signaling pathway Enhanced laser thermal ablation for the in vitro treatment of liver cancer by specific delivery of multiwalled carbon nanotubes functionalized with human serum albumin Identification of novel androgen-regulated pathways and mRNA isoforms through genome-wide exon-specific profiling of the LNCaP transcriptome.Inhibition of Adipogenesis by Oligonol through Akt-mTOR Inhibition in 3T3-L1 Adipocytes.Inhibition of EGFR-AKT axis results in the suppression of ovarian tumors in vitro and in preclinical mouse model.Nitric oxide is the key mediator of death induced by fisetin in human acute monocytic leukemia cells.Dual inhibition of phosphatidylinositol 3-kinase/Akt and mammalian target of rapamycin signaling in human nonsmall cell lung cancer cells by a dietary flavonoid fisetin.Andrographolide Analogue Induces Apoptosis and Autophagy Mediated Cell Death in U937 Cells by Inhibition of PI3K/Akt/mTOR Pathway.Dietary flavonoid fisetin increases abundance of high-molecular-mass hyaluronan conferring resistance to prostate oncogenesis.The Natural Flavonoid Fisetin Inhibits Cellular Proliferation of Hepatic, Colorectal, and Pancreatic Cancer Cells through Modulation of Multiple Signaling Pathways Fisetin, a phytochemical, potentiates sorafenib-induced apoptosis and abrogates tumor growth in athymic nude mice implanted with BRAF-mutated melanoma cells Fisetin inhibits hyperglycemia-induced proinflammatory cytokine production by epigenetic mechanisms.Paclitaxel and the dietary flavonoid fisetin: a synergistic combination that induces mitotic catastrophe and autophagic cell death in A549 non-small cell lung cancer cells.Targeting the AMP-Activated Protein Kinase for Cancer Prevention and Therapy.1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione Induces G1 Cell Cycle Arrest and Autophagy in HeLa Cervical Cancer Cells.Icariside II, a natural mTOR inhibitor, disrupts aberrant energy homeostasis via suppressing mTORC1-4E-BP1 axis in sarcoma cells Androgen receptor (AR) positive vs negative roles in prostate cancer cell deaths including apoptosis, anoikis, entosis, necrosis and autophagic cell death.Fisetin inhibits human melanoma cell invasion through promotion of mesenchymal to epithelial transition and by targeting MAPK and NFκB signaling pathways The Healthy Effects of Strawberry Polyphenols: Which Strategy behind Antioxidant Capacity?Fisetin-induced apoptosis of human oral cancer SCC-4 cells through reactive oxygen species production, endoplasmic reticulum stress, caspase-, and mitochondria-dependent signaling pathways.Fisetin Enhances Chemotherapeutic Effect of Cabazitaxel against Human Prostate Cancer Cells.Dietary flavonoid fisetin for cancer prevention and treatment.Exploring the molecular targets of dietary flavonoid fisetin in cancer.Increased reactive oxygen species levels cause ER stress and cytotoxicity in andrographolide treated colon cancer cells.Fisetin, a dietary flavonoid, induces apoptosis of cancer cells by inhibiting HSF1 activity through blocking its binding to the hsp70 promoter.Fisetin induces apoptosis in human nonsmall lung cancer cells via a mitochondria-mediated pathway.Fisetin and Its Role in Chronic Diseases.Involvement of ER stress and activation of apoptotic pathways in fisetin induced cytotoxicity in human melanoma.Fisetin inhibits human melanoma cell growth through direct binding to p70S6K and mTOR: findings from 3-D melanoma skin equivalents and computational modeling Neferine attenuates the protein level and toxicity of mutant huntingtin in PC-12 cells via induction of autophagy.Tanshinone IIA induces autophagic cell death via activation of AMPK and ERK and inhibition of mTOR and p70 S6K in KBM-5 leukemia cells.

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Fisetin induces autophagic cell death through suppression of mTOR signaling pathway in prostate cancer cells.

http://www.wikidata.org/entity/Q34042356

description

2010 nî lūn-bûn

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2010 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հունիսին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Fisetin induces autophagic cel ...... hway in prostate cancer cells.

@ast

Fisetin induces autophagic cel ...... hway in prostate cancer cells.

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Fisetin induces autophagic cel ...... hway in prostate cancer cells.

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type

label

Fisetin induces autophagic cel ...... hway in prostate cancer cells.

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Fisetin induces autophagic cel ...... hway in prostate cancer cells.

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Fisetin induces autophagic cel ...... hway in prostate cancer cells.

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prefLabel

Fisetin induces autophagic cel ...... hway in prostate cancer cells.

@ast

Fisetin induces autophagic cel ...... hway in prostate cancer cells.

@en

Fisetin induces autophagic cel ...... hway in prostate cancer cells.

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Farrukh Afaq

http://www.w3.org/2001/XMLSchema#string

Fatima H Khusro

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Hasan Mukhtar

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Jeremy J Johnson

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Naghma Khan

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Yewseok Suh

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Chemotherapy for hormone-refractory prostate cancer

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton

The translation initiation factor eIF-4E binds to a common motif shared by the translation factor eIF-4 gamma and the translational repressors 4E-binding proteins

LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

Phosphorylation of eucaryotic translation initiation factor 4B Ser422 is modulated by S6 kinases

Perifosine inhibits mammalian target of rapamycin signaling through facilitating degradation of major components in the mTOR axis and induces autophagy

TSC2 mediates cellular energy response to control cell growth and survival

Defining the role of mTOR in cancer

4E-binding protein 1: a key molecular "funnel factor" in human cancer with clinical implications

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