Mutation of Glu-361 in human endothelial nitric-oxide synthase selectively abolishes L-arginine binding without perturbing the behavior of heme and other redox centers
about
Nitric oxide synthases: structure, function and inhibitionRegulation of cellular communication by signaling microdomains in the blood vessel wall.The autoinhibitory control element and calmodulin conspire to provide physiological modulation of endothelial and neuronal nitric oxide synthase activity.Superoxide generation by endothelial nitric oxide synthase: the influence of cofactors.Phosphorylation inactivation of endothelial nitric oxide synthesis in pulmonary arterial hypertension.Proteomic analysis of the NOS2 interactome in human airway epithelial cellsRegulation of endothelial nitric oxide synthase and high-density lipoprotein quality by estradiol in cardiovascular pathology.Effects of Asp-369 and Arg-372 mutations on heme environment and function in human endothelial nitric-oxide synthase.Thioredoxin-interacting protein (Txnip) is a feedback regulator of S-nitrosylation.Signaling by eNOS through a superoxide-dependent p42/44 mitogen-activated protein kinase pathway.Characterization of the roles of the 594-645 region in human endothelial nitric-oxide synthase in regulating calmodulin binding and electron transfer.L-arginine binding to nitric-oxide synthase. The role of H-bonds to the nonreactive guanidinium nitrogens.Autoinhibition of endothelial nitric-oxide synthase. Identification of an electron transfer control element.Structural basis for isoform-selective inhibition in nitric oxide synthase.Calmodulin activates intersubunit electron transfer in the neuronal nitric-oxide synthase dimer.Distinct influence of N-terminal elements on neuronal nitric-oxide synthase structure and catalysis.Structural elements contribute to the calcium/calmodulin dependence on enzyme activation in human endothelial nitric-oxide synthase.Inhibition of p90 ribosomal S6 kinase-mediated CCAAT/enhancer-binding protein beta activation and cyclooxygenase-2 expression by salicylate.Domain swapping in inducible nitric-oxide synthase. Electron transfer occurs between flavin and heme groups located on adjacent subunits in the dimer.The C331A mutant of neuronal nitric-oxide synthase is defective in arginine binding.The crucial roles of Asp-314 and Thr-315 in the catalytic activation of molecular oxygen by neuronal nitric-oxide synthase. A site-directed mutagenesis study.Importance of Val567 on heme environment and substrate recognition of neuronal nitric oxide synthase
P2860
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P2860
Mutation of Glu-361 in human endothelial nitric-oxide synthase selectively abolishes L-arginine binding without perturbing the behavior of heme and other redox centers
description
1997 nî lūn-bûn
@nan
1997 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի մարտին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Mutation of Glu-361 in human e ...... f heme and other redox centers
@ast
Mutation of Glu-361 in human e ...... f heme and other redox centers
@en
Mutation of Glu-361 in human e ...... f heme and other redox centers
@nl
type
label
Mutation of Glu-361 in human e ...... f heme and other redox centers
@ast
Mutation of Glu-361 in human e ...... f heme and other redox centers
@en
Mutation of Glu-361 in human e ...... f heme and other redox centers
@nl
prefLabel
Mutation of Glu-361 in human e ...... f heme and other redox centers
@ast
Mutation of Glu-361 in human e ...... f heme and other redox centers
@en
Mutation of Glu-361 in human e ...... f heme and other redox centers
@nl
P2093
P2860
P356
P1476
Mutation of Glu-361 in human e ...... f heme and other redox centers
@en
P2093
P2860
P304
P356
10.1074/JBC.272.10.6114
P407
P577
1997-03-01T00:00:00Z