Apoa5 Q139X truncation predisposes to late-onset hyperchylomicronemia due to lipoprotein lipase impairment. - Wikidata - awgldk - TriplyDB

Apoa5 Q139X truncation predisposes to late-onset hyperchylomicronemia due to lipoprotein lipase impairment.

Apoa5 Q139X truncation predisposes to late-onset hyperchylomicronemia due to lipoprotein lipase impairment.

http://www.wikidata.org/entity/Q34048473

about

Molecular processes that handle -- and mishandle -- dietary lipids Apolipoprotein A-V gene therapy for disease prevention / treatment:a critical analysis Influence of apolipoprotein A-V on the metabolic fate of triacylglycerol APOA5 Ala315>Val, identified in patients with severe hypertriglyceridemia, is a common mutation with no major effects on plasma lipid levels Post-heparin LPL activity measurement using VLDL as a substrate: a new robust method for routine assessment of plasma triglyceride lipolysis defects The C terminus of apolipoprotein A-V modulates lipid-binding activity.Atherogenesis and metabolic dysregulation in LDL receptor-knockout rats.Lipoprotein lipase activity and mass, apolipoprotein C-II mass and polymorphisms of apolipoproteins E and A5 in subjects with prior acute hypertriglyceridaemic pancreatitis Apolipoprotein A5 and lipoprotein lipase interact to modulate anthropometric measures in Hispanics of Caribbean origin.Novel LMF1 nonsense mutation in a patient with severe hypertriglyceridemia GPIHBP1: an endothelial cell molecule important for the lipolytic processing of chylomicrons.The N-terminus of apolipoprotein A-V adopts a helix bundle molecular architecture.Interactions between the APOA5 -1131T>C and the FEN1 10154G>T polymorphisms on ω6 polyunsaturated fatty acids in serum phospholipids and coronary artery disease.Intravenous injection of apolipoprotein A-V reconstituted high-density lipoprotein decreases hypertriglyceridemia in apoav-/- mice and requires glycosylphosphatidylinositol-anchored high-density lipoprotein-binding protein 1.APOA5 Q97X mutation identified through homozygosity mapping causes severe hypertriglyceridemia in a Chilean consanguineous family.Biogenesis of apolipoprotein A-V and its impact on VLDL triglyceride secretion.Association between CETP, MLXIPL, and TOMM40 polymorphisms and serum lipid levels in a Latvian population.Lipoprotein lipase: from gene to obesity.Type 1 hyperlipoproteinemia and recurrent acute pancreatitis due to lipoprotein lipase antibody in a young girl with Sjogren's syndrome.The role of CREB-H transcription factor in triglyceride metabolism.Give me A5 for lipoprotein hydrolysis!Determinants of plasma apolipoprotein A-V and APOA5 gene transcripts in humans.ApoE2-associated hypertriglyceridemia is ameliorated by increased levels of apoA-V but unaffected by apoC-III deficiency Evaluation of seven common lipid associated loci in a large Indian sib pair study.Structural and functional analysis of APOA5 mutations identified in patients with severe hypertriglyceridemia.Intracellular lipid droplet targeting by apolipoprotein A-V requires the carboxyl-terminal segment Gene transfer of apolipoprotein A-V improves the hypertriglyceridemic phenotype of apoa5 (-/-) mice.The APOA5 rs662799 polymorphism is associated with dyslipidemia and the severity of coronary heart disease in Chinese women.An APOA5 3' UTR variant associated with plasma triglycerides triggers APOA5 downregulation by creating a functional miR-485-5p binding site.Apolipoprotein A-V N-terminal domain lipid interaction properties in vitro explain the hypertriglyceridemic phenotype associated with natural truncation mutants.Association of APOA5 rs662799 and rs3135506 polymorphisms with arterial hypertension in Moroccan patients.The complex genetic basis of plasma triglycerides.The pathophysiology of intestinal lipoprotein production.Apolipoprotein A-V association with intracellular lipid droplets.Apolipoprotein A-V, triglycerides and risk of coronary artery disease: the prospective Epic-Norfolk Population Study.The carboxyl-terminal segment of apolipoprotein A-V undergoes a lipid-induced conformational change.Dietary oxidized linoleic acid lowers triglycerides via APOA5/APOClll dependent mechanisms.Association of APOA5 T1131C polymorphism and risk of coronary artery disease.Dietary capsanthin, the main carotenoid in paprika (Capsicum annuum), alters plasma high-density lipoprotein-cholesterol levels and hepatic gene expression in rats.Hypertriglyceridaemia and low plasma HDL in a patient with apolipoprotein A-V deficiency due to a novel mutation in the APOA5 gene.

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P2860

Apoa5 Q139X truncation predisposes to late-onset hyperchylomicronemia due to lipoprotein lipase impairment.

http://www.wikidata.org/entity/Q34048473

description

2005 nî lūn-bûn

@nan

2005 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

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2005 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2005年の論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年论文

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name

Apoa5 Q139X truncation predisp ...... lipoprotein lipase impairment.

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Apoa5 Q139X truncation predisp ...... lipoprotein lipase impairment.

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Apoa5 Q139X truncation predisp ...... lipoprotein lipase impairment.

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type

label

Apoa5 Q139X truncation predisp ...... lipoprotein lipase impairment.

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Apoa5 Q139X truncation predisp ...... lipoprotein lipase impairment.

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Apoa5 Q139X truncation predisp ...... lipoprotein lipase impairment.

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prefLabel

Apoa5 Q139X truncation predisp ...... lipoprotein lipase impairment.

@ast

Apoa5 Q139X truncation predisp ...... lipoprotein lipase impairment.

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Apoa5 Q139X truncation predisp ...... lipoprotein lipase impairment.

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Journal of Clinical Investigation

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Apoa5 Q139X truncation predisp ...... lipoprotein lipase impairment.

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Agnès Sassolas

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Bruno Verges

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Christophe Marçais

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Jamila Fruchart-Najib

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Jocelyne Drai

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Laurence Perrot

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Len A Pennacchio

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Micheline Merlin

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Philippe Moulin

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Stéphane Billon

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P2860

Apolipoprotein A-V: a novel apolipoprotein associated with an early phase of liver regeneration

An apolipoprotein influencing triglycerides in humans and mice revealed by comparative sequencing

Mechanism of triglyceride lowering in mice expressing human apolipoprotein A5

Apolipoprotein A-V-heparin interactions: implications for plasma lipoprotein metabolism

Structure and interfacial properties of human apolipoprotein A-V

Relative contribution of variation within the APOC3/A4/A5 gene cluster in determining plasma triglycerides

Genetic variants in Apolipoprotein AV alter triglyceride concentrations in pregnancy

T-1131-->C polymorphism within the apolipoprotein AV gene in hypertriglyceridemic individuals

The genetic effect of the apoprotein AV gene on the serum triglyceride level in Japanese

Two independent apolipoprotein A5 haplotypes influence human plasma triglyceride levels

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2862-2869

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10.1172/JCI24471

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10

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115

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Jean-Charles Fruchart

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2005-10-01T00:00:00Z

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7565436

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16200213

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