Survival of human multiple myeloma cells is dependent on MUC1 C-terminal transmembrane subunit oncoprotein function.
about
Inhibition of the MUC1-C oncoprotein induces multiple myeloma cell death by down-regulating TIGAR expression and depleting NADPHMUC1-C Oncoprotein Blocks Terminal Differentiation of Chronic Myelogenous Leukemia Cells by a ROS-Mediated MechanismTargeting MUC1-C is synergistic with bortezomib in downregulating TIGAR and inducing ROS-mediated myeloma cell death.MUC1c regulates cell survival in pancreatic cancer by preventing lysosomal permeabilization.Terminal differentiation of chronic myelogenous leukemia cells is induced by targeting of the MUC1-C oncoprotein.Combination of curcumin and bicalutamide enhanced the growth inhibition of androgen-independent prostate cancer cells through SAPK/JNK and MEK/ERK1/2-mediated targeting NF-κB/p65 and MUC1-C.Mucin 1 Regulates Cox-2 Gene in Pancreatic Cancer.Mucin 1 is a potential therapeutic target in cutaneous T-cell lymphoma.Targeting cysteine-mediated dimerization of the MUC1-C oncoprotein in human cancer cellsThe generation and analyses of a novel combination of recombinant adenovirus vaccines targeting three tumor antigens as an immunotherapeutic.MUC1-C drives MYC in multiple myelomaMUC1 (CD227): a multi-tasked molecule.Bone marrow stroma protects myeloma cells from cytotoxic damage via induction of the oncoprotein MUC1.MUC1 in hematological malignancies.Identification and characterization of agonist epitopes of the MUC1-C oncoprotein.Targeting MUC1-C suppresses polycomb repressive complex 1 in multiple myeloma.MUC1-C is a target in lenalidomide resistant multiple myeloma.MUC1 inhibition leads to decrease in PD-L1 levels via upregulation of miRNAs.Expression of Mucin-1 in multiple myeloma and its precursors: correlation with glycosylation and subcellular localization
P2860
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P2860
Survival of human multiple myeloma cells is dependent on MUC1 C-terminal transmembrane subunit oncoprotein function.
description
2010 nî lūn-bûn
@nan
2010 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Survival of human multiple mye ...... subunit oncoprotein function.
@ast
Survival of human multiple mye ...... subunit oncoprotein function.
@en
Survival of human multiple mye ...... subunit oncoprotein function.
@nl
type
label
Survival of human multiple mye ...... subunit oncoprotein function.
@ast
Survival of human multiple mye ...... subunit oncoprotein function.
@en
Survival of human multiple mye ...... subunit oncoprotein function.
@nl
prefLabel
Survival of human multiple mye ...... subunit oncoprotein function.
@ast
Survival of human multiple mye ...... subunit oncoprotein function.
@en
Survival of human multiple mye ...... subunit oncoprotein function.
@nl
P2093
P2860
P356
P1476
Survival of human multiple mye ...... subunit oncoprotein function.
@en
P2093
Baldev Vasir
David Avigan
Donald Kufe
Michio Kosugi
Rehan Ahmad
Surender Kharbanda
Turner Kufe
P2860
P304
P356
10.1124/MOL.110.065011
P577
2010-05-05T00:00:00Z