The acyl-coenzyme A: cholesterol acyltransferase inhibitor CI-1011 reverses diffuse brain amyloid pathology in aged amyloid precursor protein transgenic mice.

The acyl-coenzyme A: cholesterol acyltransferase inhibitor CI-1011 reverses diffuse brain amyloid pathology in aged amyloid precursor protein transgenic mice.

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http://www.wikidata.org/entity/Q34052428
Cholesterol homeostasis: a key to prevent or slow down neurodegenerationACAT1/SOAT1 as a therapeutic target for Alzheimer's diseaseSmall molecule p75NTR ligands reduce pathological phosphorylation and misfolding of tau, inflammatory changes, cholinergic degeneration, and cognitive deficits in AβPP(L/S) transgenic mice.Neuroinflammation and related neuropathologies in APPSL mice: further value of this in vivo model of Alzheimer's disease.Inhibiting ACAT1/SOAT1 in microglia stimulates autophagy-mediated lysosomal proteolysis and increases Aβ1-42 clearanceNon-selective calcium channel blocker bepridil decreases secondary pathology in mice after photothrombotic cortical lesionAtherosclerosis and Alzheimer--diseases with a common cause? Inflammation, oxysterols, vasculatureAcyl-coenzyme A:cholesterol acyltransferase 1 blockage enhances autophagy in the neurons of triple transgenic Alzheimer's disease mouse and reduces human P301L-tau content at the presymptomatic stage.Palmitoylation of amyloid precursor protein regulates amyloidogenic processing in lipid raftsAcat1 knockdown gene therapy decreases amyloid-β in a mouse model of Alzheimer's disease.The role of cholesterol metabolism in Alzheimer's disease.Cellular Cholesterol Homeostasis in Alzheimer's Disease.Acyl-coenzyme A:cholesterol acyltransferase 1 - significance of single-nucleotide polymorphism at residue 526 and the role of Pro347 near the fifth transmembrane domain.Impacts of membrane biophysics in Alzheimer's disease: from amyloid precursor protein processing to aβ Peptide-induced membrane changes.Alzheimer's associated amyloid and tau deposition co-localizes with a homeostatic myelin repair pathway in two mouse models of post-stroke mixed dementia
P2860

The acyl-coenzyme A: cholesterol acyltransferase inhibitor CI-1011 reverses diffuse brain amyloid pathology in aged amyloid precursor protein transgenic mice.

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http://www.wikidata.org/entity/Q34052428
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2010 nî lūn-bûn
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2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
The acyl-coenzyme A: cholester ...... ursor protein transgenic mice.
@ast
The acyl-coenzyme A: cholester ...... ursor protein transgenic mice.
@en
The acyl-coenzyme A: cholester ...... ursor protein transgenic mice.
@nl
type
label
The acyl-coenzyme A: cholester ...... ursor protein transgenic mice.
@ast
The acyl-coenzyme A: cholester ...... ursor protein transgenic mice.
@en
The acyl-coenzyme A: cholester ...... ursor protein transgenic mice.
@nl
prefLabel
The acyl-coenzyme A: cholester ...... ursor protein transgenic mice.
@ast
The acyl-coenzyme A: cholester ...... ursor protein transgenic mice.
@en
The acyl-coenzyme A: cholester ...... ursor protein transgenic mice.
@nl
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The acyl-coenzyme A: cholester ...... cursor protein transgenic mice
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P2093
P2860
P304
P31
P356
10.1097/NEN.0B013E3181E77ED9
P433
P478
P50
P577
P698
P921
P932