High-throughput RNA interference screening using pooled shRNA libraries and next generation sequencing.
about
Cancer Cell Line Panels Empower Genomics-Based Discovery of Precision Cancer MedicinePhotostick: a method for selective isolation of target cells from cultureGenome-wide profiling of genetic synthetic lethality identifies CDK12 as a novel determinant of PARP1/2 inhibitor sensitivity.RAS Synthetic Lethal Screens Revisited: Still Seeking the Elusive Prize?ScreenBEAM: a novel meta-analysis algorithm for functional genomics screens via Bayesian hierarchical modelingThe Power Decoder Simulator for the Evaluation of Pooled shRNA Screen PerformanceNovel high throughput pooled shRNA screening identifies NQO1 as a potential drug target for host directed therapy for tuberculosisData Analysis for High-Throughput RNAi Screening.Functional toxicology: tools to advance the future of toxicity testing.Use of RNAi screens to uncover resistance mechanisms in cancer cells and identify synthetic lethal interactions.TOPS: a versatile software tool for statistical analysis and visualization of combinatorial gene-gene and gene-drug interaction screens.CRISPulator: a discrete simulation tool for pooled genetic screensPooled shRNA screen for sensitizers to inhibition of the mitotic regulator polo-like kinase (PLK1).Optimized PCR conditions and increased shRNA fold representation improve reproducibility of pooled shRNA screens.Using functional genomics to overcome therapeutic resistance in hematological malignancies.Applications of RNA interference high-throughput screening technology in cancer biology and virologyA Pooled shRNA Screen Identifies Rbm15, Spen, and Wtap as Factors Required for Xist RNA-Mediated Silencing.Genome-wide RNAi screening identifies genes inhibiting the migration of glioblastoma cells.Developing microRNA screening as a functional genomics tool for disease research.Integrative genomic and functional profiling of the pancreatic cancer genome.Design and analysis of Bar-seq experiments.edgeR: a versatile tool for the analysis of shRNA-seq and CRISPR-Cas9 genetic screens.Hypoxic regulation of RIOK3 is a major mechanism for cancer cell invasion and metastasisPooled screening for antiproliferative inhibitors of protein-protein interactions.Metabolic Rewiring by Oncogenic BRAF V600E Links Ketogenesis Pathway to BRAF-MEK1 SignalingSources of Error in Mammalian Genetic Screens.Genome-wide functional analysis using the barcode sequence alignment and statistical analysis (Barcas) tool.Identification of novel cancer therapeutic targets using a designed and pooled shRNA library screenGenome-wide barcoded transposon screen for cancer drug sensitivity in haploid mouse embryonic stem cells.In Vivo RNAi Screen Unveils PPARγ as a Regulator of Hematopoietic Stem Cell HomeostasisHDAC6 activity is a non-oncogene addiction hub for inflammatory breast cancersIn vivo RNAi screens: concepts and applications.Quantitative genetic-interaction mapping in mammalian cells.Functional genomics identifies five distinct molecular subtypes with clinical relevance and pathways for growth control in epithelial ovarian cancer.Functional genomic screening to enhance oncolytic virotherapy.Cancer biomarker discovery: current status and future perspectives.A Perspective on the Future of High-Throughput RNAi Screening: Will CRISPR Cut Out the Competition or Can RNAi Help Guide the Way?High-Throughput RNAi Screening Identifies a Role for the Osteopontin Pathway in Proliferation and Migration of Human Aortic Smooth Muscle Cells.Dissecting neural differentiation regulatory networks through epigenetic footprinting.A computational algorithm to predict shRNA potency.
P2860
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P2860
High-throughput RNA interference screening using pooled shRNA libraries and next generation sequencing.
description
2011 nî lūn-bûn
@nan
2011 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
High-throughput RNA interferen ...... nd next generation sequencing.
@ast
High-throughput RNA interferen ...... nd next generation sequencing.
@en
High-throughput RNA interferen ...... nd next generation sequencing.
@nl
type
label
High-throughput RNA interferen ...... nd next generation sequencing.
@ast
High-throughput RNA interferen ...... nd next generation sequencing.
@en
High-throughput RNA interferen ...... nd next generation sequencing.
@nl
prefLabel
High-throughput RNA interferen ...... nd next generation sequencing.
@ast
High-throughput RNA interferen ...... nd next generation sequencing.
@en
High-throughput RNA interferen ...... nd next generation sequencing.
@nl
P2093
P2860
P50
P1433
P1476
High-throughput RNA interferen ...... nd next generation sequencing.
@en
P2093
Ana M Mendes-Pereira
Costas Mitsopoulos
Cristina Lombardelli
David Sims
Ioannis Assiotis
Iwanka Kozarewa
Jarle Hakas
Jessica Frankum
Kerry Fenwick
Maria-Antonietta Cerone
P2860
P2888
P356
10.1186/GB-2011-12-10-R104
P577
2011-10-21T00:00:00Z
P5875
P6179
1042531032