Hepatic mTORC1 controls locomotor activity, body temperature, and lipid metabolism through FGF21. - Wikidata - awgldk - TriplyDB

Hepatic mTORC1 controls locomotor activity, body temperature, and lipid metabolism through FGF21.

Hepatic mTORC1 controls locomotor activity, body temperature, and lipid metabolism through FGF21.

http://www.wikidata.org/entity/Q34060841

about

Central Amino Acid Sensing in the Control of Feeding Behavior The Mechanistic Target of Rapamycin: The Grand ConducTOR of Metabolism and Aging Decreased Consumption of Branched-Chain Amino Acids Improves Metabolic Health Hepatic Fgf21 Expression Is Repressed after Simvastatin Treatment in Mice Mtu1-Mediated Thiouridine Formation of Mitochondrial tRNAs Is Required for Mitochondrial Translation and Is Involved in Reversible Infantile Liver Injury Loss of hepatic DEPTOR alters the metabolic transition to fasting Systems Biology-Derived Discoveries of Intrinsic Clocks.Milk consumption during pregnancy increases birth weight, a risk factor for the development of diseases of civilization A muscle-liver-fat signalling axis is essential for central control of adaptive adipose remodelling.Livers with constitutive mTORC1 activity resist steatosis independent of feedback suppression of Akt.The Circadian Protein BMAL1 Regulates Translation in Response to S6K1-Mediated Phosphorylation.TORC2 mediates the heat stress response in Drosophila by promoting the formation of stress granules Forced Hepatic Overexpression of CEACAM1 Curtails Diet-Induced Insulin Resistance Circadian and feeding rhythms differentially affect rhythmic mRNA transcription and translation in mouse liver Circadian clocks govern calorie restriction-mediated life span extension through BMAL1- and IGF-1-dependent mechanisms Recent Advances in Adipose mTOR Signaling and Function: Therapeutic Prospects Multiple amino acid sensing inputs to mTORC1.Perturbed rhythmic activation of signaling pathways in mice deficient for Sterol Carrier Protein 2-dependent diurnal lipid transport and metabolism.Secreted IGFBP5 mediates mTORC1-dependent feedback inhibition of IGF-1 signalling.Circadian clock regulation of mRNA translation through eukaryotic elongation factor eEF-2 A liver stress-endocrine nexus promotes metabolic integrity during dietary protein dilution.mTOR in health and in sickness.Loss of Hepatic CEACAM1: A Unifying Mechanism Linking Insulin Resistance to Obesity and Non-Alcoholic Fatty Liver Disease Fibroblast growth factor 21 improves hepatic insulin sensitivity by inhibiting mammalian target of rapamycin complex 1 in mice.Repletion of branched chain amino acids reverses mTORC1 signaling but not improved metabolism during dietary protein dilution.A hepatic amino acid/mTOR/S6K-dependent signalling pathway modulates systemic lipid metabolism via neuronal signals.Aberrant Proteostasis of BMAL1 Underlies Circadian Abnormalities in a Paradigmatic mTOR-opathy.Glucagon and Insulin Cooperatively Stimulate Fibroblast Growth Factor 21 Gene Transcription by Increasing the Expression of Activating Transcription Factor 4.TOR-mediated regulation of metabolism in aging.FGF21 inhibitor suppresses the proliferation and migration of human umbilical vein endothelial cells through the eNOS/PI3K/AKT pathway.Alpha-Linolenic Acid-Induced Increase in Neurogenesis is a Key Factor in the Improvement in the Passive Avoidance Task After Soman Exposure.Upstream signalling of mTORC1 and its hyperactivation in type 2 diabetes (T2D).Recent Discoveries on the Role of TOR (Target of Rapamycin) Signaling in Translation in Plants.Alterations in 3-Hydroxyisobutyrate and FGF21 Metabolism Are Associated With Protein Ingestion-Induced Insulin Resistance.Role for hepatic CEACAM1 in regulating fatty acid metabolism along the adipocyte-hepatocyte axis.Short-term methionine deprivation improves metabolic health via sexually dimorphic, mTORC1-independent mechanisms.Activation of mTORC1 in skeletal muscle regulates whole-body metabolism through FGF21.Circadian clocks, diets and aging.mTOR signaling regulates central and peripheral circadian clock function.Deletion of the glucagon receptor gene before and after experimental diabetes reveals differential protection from hyperglycemia

P2860

Q28071492-427AF91F-C9E7-4B7A-8CC4-70748DB84E1C Q28276378-47FDE35B-FE89-462B-B603-DDD5CD0110A9 Q28276635-FD051193-FCB9-427B-872F-D2EB863F4FC4 Q28553822-BB7A5073-8E7C-4E6C-B77A-E675CBCEF7F9 Q28554428-36844316-CD7A-4B77-A412-9E7828A20A52 Q33600500-9D559A29-D143-47CA-8024-915EF9A5B4FB Q34551665-B8E0D2BC-0FD8-4F96-A064-26364F57EF6A Q34996173-C420ED07-C681-4D02-9650-14509D8EFC4B Q35407627-57594807-CEDE-4995-A231-912E56550979 Q35554147-484512CC-C5D7-48EC-B049-6B574D0F39E0 Q35660035-75F67C9F-A6AA-4E4C-A2DE-126AF8839811 Q35878104-BF571E48-9959-400D-B264-AA7D66921F2C Q35881723-48DC7B0A-E890-43E0-B929-328AA885634D Q36331939-3498A236-9437-4F3C-ACD2-4BA30E3E7889 Q36705326-28547E3F-68A7-4DE4-A784-BA73E3492170 Q36739499-52672C76-7435-4C37-8AF9-F57F7ABA3E48 Q36751634-FA2C3EBD-4273-4A70-9731-F26120FCDAFE Q36819805-6AF4256C-B44F-413C-BC4C-064A55ACAFCC Q37210786-1F8C8E37-4D91-4EC8-BABD-5C65A75938B8 Q37213851-867A1187-66E2-4217-90DC-D84284A73134 Q37217436-B08EA6AC-6FBC-4E2B-8A35-A520BC55B6FE Q38590634-195BB2B5-C0E6-4569-A9C7-8D05663FFFB1 Q39128964-44730E78-4E1F-4C0C-BB3D-98BFAC5B9E78 Q40880973-7C3BF915-C1E2-4B93-99FD-8D621AC907C3 Q41069355-914DD4E2-C292-4E48-B6FA-6A21483C627D Q41488066-1B9357BB-A66E-4DA2-91E3-B88789D849FE Q41720015-9D346DCA-53B2-419B-9524-5EEE5A108E58 Q45052537-FF9A01EF-E780-4857-BDF3-174B9C35EB5B Q45863420-D719CFB6-2808-4110-8CDB-88117B7CBD32 Q47220838-7BF38666-80AC-437F-BEB4-66CCAA2BF95D Q47656370-697E8577-47F2-4667-9146-BFB66A467358 Q49413554-E31CC928-9642-46A6-9EED-6D50B9131E2F Q50083747-ECB259CF-C456-443C-927A-605C3A7239C4 Q51019495-01FDA13B-9BE1-42DC-8E6B-F1C0D0DE6D5C Q51365355-A6B00EBE-0D58-4EA5-9620-099A69DAFB4E Q52385007-713C858A-3C51-43B1-ACCB-F3DDD236B9EE Q53438320-F8D38F3E-D164-4806-A237-63C8DE464BCB Q54130511-82CA69CE-CD44-4B1C-95E4-BE224E914EC5 Q54960744-5B159995-561E-4C99-8264-8D9DD0F130E7 Q58732217-6683FEFC-0FDD-4D17-BCA7-F6EFFCA75A21

P2860

Hepatic mTORC1 controls locomotor activity, body temperature, and lipid metabolism through FGF21.

http://www.wikidata.org/entity/Q34060841

description

2014 nî lūn-bûn

@nan

2014 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի հուլիսին հրատարակված գիտական հոդված

@hy

2014年の論文

@ja

2014年論文

@yue

2014年論文

@zh-hant

2014年論文

@zh-hk

2014年論文

@zh-mo

2014年論文

@zh-tw

2014年论文

@wuu

name

Hepatic mTORC1 controls locomo ...... ipid metabolism through FGF21.

@ast

Hepatic mTORC1 controls locomo ...... ipid metabolism through FGF21.

@en

Hepatic mTORC1 controls locomo ...... ipid metabolism through FGF21.

@nl

type

label

Hepatic mTORC1 controls locomo ...... ipid metabolism through FGF21.

@ast

Hepatic mTORC1 controls locomo ...... ipid metabolism through FGF21.

@en

Hepatic mTORC1 controls locomo ...... ipid metabolism through FGF21.

@nl

prefLabel

Hepatic mTORC1 controls locomo ...... ipid metabolism through FGF21.

@ast

Hepatic mTORC1 controls locomo ...... ipid metabolism through FGF21.

@en

Hepatic mTORC1 controls locomo ...... ipid metabolism through FGF21.

@nl

P1433

Q34060841-C83F30B1-AEA9-4E22-B237-338887417877

P1476

Q34060841-43C69133-ADE1-4104-9BBE-838919EF281F

P2093

Q34060841-1522CFC2-8B36-4D9B-A998-BB25CC81EDBD

Q34060841-47BDE066-D179-4A25-BF8A-C808249A8170

Q34060841-D8BB4E8A-8261-4E83-A2CD-40B2EF757BEF

Q34060841-F2B7A96B-71DE-4B3F-A271-4A61BBF8D8D5

Q34060841-F354FBC4-A4FB-4EF0-A41D-7677345AD837

Q34060841-F856FF22-AA20-4871-8B12-6DF48C25EB60

Q34060841-FB9AC2BF-E508-4171-A133-468C1DC70AA5

P2860

Q34060841-04143146-B067-4789-9286-325691FE9DCF

Q34060841-05B2F504-A983-4905-A1F9-673D12DCC1D2

Q34060841-08585895-3022-4F0C-A5ED-9FF34A656DAF

Q34060841-09733A46-8838-4644-8666-182FDF86A4D5

Q34060841-10101F08-4F9B-48E2-A9D6-D1E316CDDB14

Q34060841-14D97566-E87E-46F1-8553-32B15C51D2C9

Q34060841-1CCA3B15-263A-4998-9DD3-14FC5B9DE620

Q34060841-23AE9685-88D2-4DC2-8B66-860E38CAA344

Q34060841-25C0F184-B622-4883-B117-5B99E9585E64

Q34060841-278DD0CD-39E7-4C8D-BF94-3B0E72A134B5

P304

Q34060841-2272AF99-9FA1-4C99-A0A9-5C5203E464FC

P31

Q34060841-66D7922A-8F7A-44B6-B0B1-9DAA9D555F69

P356

Q34060841-0243E888-DEB8-41E2-9864-EFBB0D7C4063

P407

Q34060841-7728EC0E-A36F-49B3-8EC3-689008905C7E

P433

Q34060841-2BD89C97-4BB9-40AB-809B-179533B2CDBB

P478

Q34060841-83D14752-1F02-47BB-A68A-044C9EB841CB

P50

Q34060841-3F3F464B-C7BB-4ED8-B139-8D8FD87F9BF8

Q34060841-F283498B-B318-4293-AE9A-254BA32CF1B1

Q34060841-F40CBDA3-5D37-46EB-AAE4-CDAF437759DB

P577

Q34060841-02D73FDC-914A-485B-AAE7-24E5C74E1FB9

P5875

Q34060841-0CD1026E-4655-42CD-AC2E-0BAA7CDC0723

P698

Q34060841-48988225-3958-4F18-B9CF-85BF5373140F

P932

Q34060841-5362CA1E-66FB-4829-82AC-C6C1F92293DF

P356

PNAS.1412047111

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Hepatic mTORC1 controls locomo ...... lipid metabolism through FGF21

@en

P2093

Francesca Trapani

http://www.w3.org/2001/XMLSchema#string

Luigi Terracciano

http://www.w3.org/2001/XMLSchema#string

Marion Cornu

http://www.w3.org/2001/XMLSchema#string

Michael N Hall

http://www.w3.org/2001/XMLSchema#string

Uwe Sauer

http://www.w3.org/2001/XMLSchema#string

Verena Albert

http://www.w3.org/2001/XMLSchema#string

Wolfgang Oppliger

http://www.w3.org/2001/XMLSchema#string

P2860

Identification of a novel FGF, FGF-21, preferentially expressed in the liver

Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton

Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive

Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control

SIRT1 regulates circadian clock gene expression through PER2 deacetylation

The NAD+-dependent deacetylase SIRT1 modulates CLOCK-mediated chromatin remodeling and circadian control

mTOR signaling in growth control and disease

FGF21 induces PGC-1alpha and regulates carbohydrate and fatty acid metabolism during the adaptive starvation response

PGC-1alpha deficiency causes multi-system energy metabolic derangements: muscle dysfunction, abnormal weight control and hepatic steatosis

The circadian clock coordinates ribosome biogenesis

P304

11592-11599

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1073/PNAS.1412047111

http://www.w3.org/2001/XMLSchema#string

P407

P433

32

http://www.w3.org/2001/XMLSchema#string

P478

111

http://www.w3.org/2001/XMLSchema#string

P50

Aaron M. Robitaille

P577

2014-07-31T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

264432618

http://www.w3.org/2001/XMLSchema#string

P698

25082895

http://www.w3.org/2001/XMLSchema#string

P932

4136616

http://www.w3.org/2001/XMLSchema#string