Thrombospondin1 deficiency reduces obesity-associated inflammation and improves insulin sensitivity in a diet-induced obese mouse model. - Wikidata - awgldk - TriplyDB

Thrombospondin1 deficiency reduces obesity-associated inflammation and improves insulin sensitivity in a diet-induced obese mouse model.

Thrombospondin1 deficiency reduces obesity-associated inflammation and improves insulin sensitivity in a diet-induced obese mouse model.

http://www.wikidata.org/entity/Q34062545

about

Adipose extracellular matrix remodelling in obesity and insulin resistance Omentum and bone marrow: how adipocyte-rich organs create tumour microenvironments conducive for metastatic progression Presence of anti-ADAMTS13 antibodies in obesity.Increasing cGMP-dependent protein kinase activity attenuates unilateral ureteral obstruction-induced renal fibrosis.Dendritic cell-derived thrombospondin-1 is critical for the generation of the ocular surface Th17 response to desiccating stress.Transgenic increase in N-3/n-6 Fatty Acid ratio reduces maternal obesity-associated inflammation and limits adverse developmental programming in mice Exogenous hydrogen sulfide mitigates the fatty liver in obese mice through improving lipid metabolism and antioxidant potential.Proteomics analysis of human obesity reveals the epigenetic factor HDAC4 as a potential target for obesity CD47 deficiency protects mice from diet-induced obesity and improves whole body glucose tolerance and insulin sensitivity.Thrombospondin1 deficiency attenuates obesity-associated microvascular complications in ApoE-/- mice Revisiting the matricellular concept.Thrombospondin-1 production is enhanced by Porphyromonas gingivalis lipopolysaccharide in THP-1 cells.Thrombospondin-1 induction in the diabetic myocardium stabilizes the cardiac matrix in addition to promoting vascular rarefaction through angiopoietin-2 upregulation.Interaction of thrombospondin1 and CD36 contributes to obesity-associated podocytopathy.Thrombospondin-1 (TSP1) contributes to the development of vascular inflammation by regulating monocytic cell motility in mouse models of abdominal aortic aneurysm.Thrombospondin-1: an extracellular message delivered by macrophages that promotes aortic aneurysms Thrombospondin 1 Deficiency Ameliorates the Development of Adriamycin-Induced Proteinuric Kidney Disease.The gene expression profiles of induced pluripotent stem cells from individuals with childhood cerebral adrenoleukodystrophy are consistent with proposed mechanisms of pathogenesis Peri-adipocyte ECM remodeling in obesity and adipose tissue fibrosis.Regulation of thrombospondin-1 expression in alternatively activated macrophages and adipocytes: role of cellular cross talk and omega-3 fatty acids Thrombospondin 1 as a novel biological marker of obesity and metabolic syndrome Thrombospondin-1 regulates adiposity and metabolic dysfunction in diet-induced obesity enhancing adipose inflammation and stimulating adipocyte proliferation Dietary fat overcomes the protective activity of thrombospondin-1 signaling in the Apc(Min/+) model of colon cancer.Thrombospondin 1 mediates renal dysfunction in a mouse model of high-fat diet-induced obesity.Thrombospondin 1 activates the macrophage Toll-like receptor 4 pathway.Thrombospondin 1 mediates high-fat diet-induced muscle fibrosis and insulin resistance in male mice.Magnolia extract (BL153) ameliorates kidney damage in a high fat diet-induced obesity mouse model Contributions of adipose tissue architectural and tensile properties toward defining healthy and unhealthy obesity.Myeloid-specific IκB kinase β deficiency decreases atherosclerosis in low-density lipoprotein receptor-deficient mice.Thrombospondins: old players, new games Invoking the power of thrombospondins: regulation of thrombospondins expression Thrombospondin 1 Suppresses Insulin Signaling in C2C12 Myotubes.Role of thrombospondin 1 in liver diseases.Identification of novel putative adipomyokines by a cross-species annotation of secretomes and expression profiles.The role of thrombospondin (TSP)-1 in obesity and diabetes.Feeding sugar to tumors: with a supplement of miR?Thrombospondin-1 regulation of latent TGF-β activation: A therapeutic target for fibrotic disease.Thrombospondin-1: the good, the bad, and the complicated.

P2860

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P2860

Thrombospondin1 deficiency reduces obesity-associated inflammation and improves insulin sensitivity in a diet-induced obese mouse model.

http://www.wikidata.org/entity/Q34062545

description

2011 nî lūn-bûn

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2011 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

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2011 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

Thrombospondin1 deficiency red ...... iet-induced obese mouse model.

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Thrombospondin1 deficiency red ...... iet-induced obese mouse model.

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Thrombospondin1 deficiency red ...... iet-induced obese mouse model.

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Thrombospondin1 deficiency red ...... iet-induced obese mouse model.

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Thrombospondin1 deficiency red ...... iet-induced obese mouse model.

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Thrombospondin1 deficiency red ...... iet-induced obese mouse model.

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Thrombospondin1 deficiency red ...... iet-induced obese mouse model.

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Thrombospondin1 deficiency red ...... iet-induced obese mouse model.

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Thrombospondin1 deficiency red ...... iet-induced obese mouse model.

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Thrombospondin1 deficiency red ...... iet-induced obese mouse model.

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Courtney Rumala

http://www.w3.org/2001/XMLSchema#string

Kate Clemons

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Shuxia Wang

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Xiaopeng Tong

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Yanzhang Li

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P2860

Isolation and characterization of a high molecular weight glycoprotein from human blood platelets

Thrombospondin 1 promotes tumor macrophage recruitment and enhances tumor cell cytotoxicity of differentiated U937 cells

A thrombin-sensitive protein of human platelet membranes

Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance

Thrombospondin causes activation of latent transforming growth factor-beta secreted by endothelial cells by a novel mechanism

Thrombospondin-induced tumor cell migration: haptotaxis and chemotaxis are mediated by different molecular domains

Obesity is associated with macrophage accumulation in adipose tissue

Internalization but not binding of thrombospondin-1 to low density lipoprotein receptor-related protein-1 requires heparan sulfate proteoglycans

Cellular internalization and degradation of thrombospondin-1 is mediated by the amino-terminal heparin binding domain (HBD). High affinity interaction of dimeric HBD with the low density lipoprotein receptor-related protein

Thrombospondin-1 is a major activator of TGF-beta1 in vivo

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