Degradable self-assembling dendrons for gene delivery: experimental and theoretical insights into the barriers to cellular uptake.
about
Peptide dendrimer/lipid hybrid systems are efficient DNA transfection reagents: structure--activity relationships highlight the role of charge distribution across dendrimer generations.Dual-degradable disulfide-containing PEI-Pluronic/DNA polyplexes: transfection efficiency and balancing protection and DNA release.Self-assembled multivalency: dynamic ligand arrays for high-affinity binding.Heparin sensing and binding - taking supramolecular chemistry towards clinical applications.Modeling the interaction between dendrimers and nucleic acids: a molecular perspective through hierarchical scales.Multivalent DNA recognition by self-assembled clusters: deciphering structural effects by fragments screening and evaluation as siRNA vectors.Degradable hybrid materials based on cationic acylhydrazone dynamic covalent polymers promote DNA complexation through multivalent interactions.Star-shaped tetraspermine enhances cellular uptake and cytotoxicity of T-oligo in prostate cancer cells.The dendrimer paradox--high medical expectations but poor clinical translation.Nanocarriers for delivery of siRNA and co-delivery of siRNA and other therapeutic agents.Emerging trends in enzyme inhibition by multivalent nanoconstructs.Bioactive clusters promoting cell penetration and nucleic acid complexation for drug and gene delivery applications: from designed to self-assembled and responsive systems.Polyamine-DNA interactions and development of gene delivery vehicles.Mastering Dendrimer Self-Assembly for Efficient siRNA Delivery: From Conceptual Design to In Vivo Efficient Gene Silencing.Investigations on dendrimer space reveal solid and liquid tumor growth-inhibition by original phosphorus-based dendrimers and the corresponding monomers and dendrons with ethacrynic acid motifs.Molecular assembly of highly symmetric molecules under a hydrogen bond framework controlled by alkyl building blocks: a simple approach to fine-tune nanoscale structures.Suppression of VEGF by reversible-PEGylated histidylated polylysine in cancer therapy.Fabrication of Low-Generation Dendrimers into Nanostructures for Efficient and Nontoxic Gene Delivery.Self-assembled multivalent RGD-peptide arrays--morphological control and integrin binding.Synthesis of pH-Cleavable dPG-Amines for Gene Delivery Application.Double-degradable responsive self-assembled multivalent arrays--temporary nanoscale recognition between dendrons and DNA.Chemical, pharmacological, and in vitro metabolic stability studies on enantiomerically pure RC-33 compounds: promising neuroprotective agents acting as σ₁ receptor agonists.Polycation-telodendrimer nanocomplexes for intracellular protein delivery.Use of nanoparticles for glioblastoma treatment: a new approach.Self-Assembled Multivalent (SAMul) Polyanion Binding-Impact of Hydrophobic Modifications in the Micellar Core on DNA and Heparin Binding at the Peripheral Cationic Ligands.Switching Multivalent DNA Complexation using Metal-Controlled Cationic Supramolecular Self-Assemblies.Multivalent helix mimetics for PPI-inhibition.Chiral recognition at self-assembled multivalent (SAMul) nanoscale interfaces - enantioselectivity in polyanion binding.High DNA-Binding Affinity and Gene-Transfection Efficacy of Bioreducible Cationic Nanomicelles with a Fluorinated Core.Morphological control of self-assembled multivalent (SAMul) heparin binding in highly competitive media.Guanidiniocarbonyl pyrrole (GCP) conjugated PAMAM-G2, a highly efficient vector for gene delivery: the importance of DNA condensation.Self-aggregation of amphiphilic [60]fullerenyl focal point functionalized PAMAM dendrons into pseudodendrimers: DNA binding involving dendriplex formationBiodegradable PEG–dendritic block copolymers: synthesis and biofunctionality assessment as vectors of siRNAGold nanoparticles stabilized by an amphiphilic pillar[5]arene: preparation, self-assembly into composite microtubes in water and application in green catalysisAn Amphiphilic Dendrimer for Effective Delivery of Small Interfering RNA and Gene Silencing In Vitro and In VivoElectrostatic binding of polyanions using self-assembled multivalent (SAMul) ligand displays - structure-activity effects on DNA/heparin bindingNanoscale self-assembled multivalent (SAMul) heparin binders in highly competitive, biologically relevant, aqueous mediaPolyglycerol-based amphiphilic dendrons as potential siRNA carriers for in vivo applicationsShape-Persistent and Adaptive Multivalency: Rigid Transgeden (TGD) and Flexible PAMAM Dendrimers for Heparin BindingEffects of a PEG additive on the biomolecular interactions of self-assembled dendron nanostructures
P2860
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P2860
Degradable self-assembling dendrons for gene delivery: experimental and theoretical insights into the barriers to cellular uptake.
description
2011 nî lūn-bûn
@nan
2011 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Degradable self-assembling den ...... e barriers to cellular uptake.
@ast
Degradable self-assembling den ...... e barriers to cellular uptake.
@en
Degradable self-assembling den ...... e barriers to cellular uptake.
@en-gb
Degradable self-assembling den ...... e barriers to cellular uptake.
@nl
type
label
Degradable self-assembling den ...... e barriers to cellular uptake.
@ast
Degradable self-assembling den ...... e barriers to cellular uptake.
@en
Degradable self-assembling den ...... e barriers to cellular uptake.
@en-gb
Degradable self-assembling den ...... e barriers to cellular uptake.
@nl
prefLabel
Degradable self-assembling den ...... e barriers to cellular uptake.
@ast
Degradable self-assembling den ...... e barriers to cellular uptake.
@en
Degradable self-assembling den ...... e barriers to cellular uptake.
@en-gb
Degradable self-assembling den ...... e barriers to cellular uptake.
@nl
P2093
P50
P356
P1476
Degradable self-assembling den ...... e barriers to cellular uptake.
@en
P2093
Daniel W Pack
Mark E Hwang
Paola Posocco
Rainer Haag
Victor W T Shum
P304
20288-20300
P356
10.1021/JA2070736
P407
P577
2011-11-28T00:00:00Z