The ryanodine receptor mediates early zymogen activation in pancreatitis. - Wikidata - awgldk - TriplyDB

The ryanodine receptor mediates early zymogen activation in pancreatitis.

The ryanodine receptor mediates early zymogen activation in pancreatitis.

http://www.wikidata.org/entity/Q34063467

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Low extracellular pH induces damage in the pancreatic acinar cell by enhancing calcium signaling.Caerulein-induced intracellular pancreatic zymogen activation is dependent on calcineurin.Cyclic AMP accelerates calcium waves in pancreatic acinar cells Dantrolene mitigates caerulein-induced pancreatitis in vivo in mice.Bile acids induce Ca2+ release from both the endoplasmic reticulum and acidic intracellular calcium stores through activation of inositol trisphosphate receptors and ryanodine receptors.The ryanodine receptor is expressed in human pancreatic acinar cells and contributes to acinar cell injury Cyclic AMP-dependent protein kinase and Epac mediate cyclic AMP responses in pancreatic acini.Risk factors for pancreatic cancer: underlying mechanisms and potential targets.IP3 receptor type 2 deficiency is associated with a secretory defect in the pancreatic acinar cell and an accumulation of zymogen granules.A novel protein kinase D inhibitor attenuates early events of experimental pancreatitis in isolated rat acini Src Dependent Pancreatic Acinar Injury Can Be Initiated Independent of an Increase in Cytosolic Calcium.Ethanol enhances carbachol-induced protease activation and accelerates Ca2+ waves in isolated rat pancreatic acini.The role of Ca2+ influx in endocytic vacuole formation in pancreatic acinar cells Redox signaling in acute pancreatitis.Calcium and reactive oxygen species in acute pancreatitis: friend or foe?Pharmacological and genetic inhibition of calcineurin protects against carbachol-induced pathological zymogen activation and acinar cell injury.Exposure to Radiocontrast Agents Induces Pancreatic Inflammation by Activation of Nuclear Factor-κB, Calcium Signaling, and Calcineurin.Raf-1 kinase inhibitory protein (RKIP) mediates ethanol-induced sensitization of secretagogue signaling in pancreatic acinar cells Tobacco carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone initiates and enhances pancreatitis responses Bidirectional Relationship Between Diabetes and Acute Pancreatitis: A Population-Based Cohort Study in Taiwan Bile acids induce pancreatic acinar cell injury and pancreatitis by activating calcineurin.Role of Ca2+ in pancreatic cell death induced by alcohol metabolites.Recent insights into the cellular mechanisms of acute pancreatitis.Mechanism of mitochondrial permeability transition pore induction and damage in the pancreas: inhibition prevents acute pancreatitis by protecting production of ATP.Preparation of pancreatic acinar cells for the purpose of calcium imaging, cell injury measurements, and adenoviral infection.Ryanodine receptors contribute to bile acid-induced pathological calcium signaling and pancreatitis in mice.Cluster of differentiation 38 (CD38) mediates bile acid-induced acinar cell injury and pancreatitis through cyclic ADP-ribose and intracellular calcium release Dantrolene: mechanisms of neuroprotection and possible clinical applications in the neurointensive care unit Effect of Chaiqinchengqi decoction on sarco/endoplasmic reticulum Ca2+-ATPase mRNA expression of pancreatic tissues in acute pancreatitis rats Protease activation during in vivo pancreatitis is dependent on calcineurin activation.Cardiocirculatory pathophysiological mechanisms in severe acute pancreatitis.Molecular mechanisms of pancreatic injury.Cellular geography of IP3 receptors, STIM and Orai: a lesson from secretory epithelial cells.Pathogenic mechanisms of acute pancreatitis.Calcium signaling in the liver Pathophysiological mechanisms in acute pancreatitis: Current understanding.The acinar cell and early pancreatitis responses.Src-mediated cortactin phosphorylation regulates actin localization and injurious blebbing in acinar cells.Lipid rafts establish calcium waves in hepatocytes.Cigarette toxin 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) induces experimental pancreatitis through α7 nicotinic acetylcholine receptors (nAChRs) in mice.

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P2860

The ryanodine receptor mediates early zymogen activation in pancreatitis.

http://www.wikidata.org/entity/Q34063467

description

2005 nî lūn-bûn

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2005 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

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2005 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2005年の論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年论文

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name

The ryanodine receptor mediates early zymogen activation in pancreatitis.

@ast

The ryanodine receptor mediates early zymogen activation in pancreatitis.

@en

The ryanodine receptor mediates early zymogen activation in pancreatitis.

@nl

type

label

The ryanodine receptor mediates early zymogen activation in pancreatitis.

@ast

The ryanodine receptor mediates early zymogen activation in pancreatitis.

@en

The ryanodine receptor mediates early zymogen activation in pancreatitis.

@nl

prefLabel

The ryanodine receptor mediates early zymogen activation in pancreatitis.

@ast

The ryanodine receptor mediates early zymogen activation in pancreatitis.

@en

The ryanodine receptor mediates early zymogen activation in pancreatitis.

@nl

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Proceedings of the National Academy of Sciences of the United States of America

P1476

The ryanodine receptor mediates early zymogen activation in pancreatitis.

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P2093

Fred S Gorelick

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Michael H Nathanson

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Priyajit Prasad

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Sohail Z Husain

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Thomas R Kolodecik

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Wayne M Grant

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P2860

Hereditary pancreatitis is caused by a mutation in the cationic trypsinogen gene

FKBP12.6 deficiency and defective calcium release channel (ryanodine receptor) function linked to exercise-induced sudden cardiac death

Gabexate for the prevention of pancreatic damage related to endoscopic retrograde cholangiopancreatography. Gabexate in digestive endoscopy--Italian Group

Multiple isoforms of the ryanodine receptor are expressed in rat pancreatic acinar cells.

Effect of ligands that increase cAMP on caerulein-induced zymogen activation in pancreatic acini.

Alcohols enhance caerulein-induced zymogen activation in pancreatic acinar cells

Trypsin activates pancreatic duct epithelial cell ion channels through proteinase-activated receptor-2.

Micromolar and submicromolar Ca2+ spikes regulating distinct cellular functions in pancreatic acinar cells.

Dantrolene--a review of its pharmacology, therapeutic use and new developments.

Effects of increased intracellular cAMP on carbachol-stimulated zymogen activation, secretion, and injury in the pancreatic acinar cell.

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14386-14391

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102

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7576971

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16186498

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