Molecular genetics and target site specificity of retroviral integration.
about
The SET domain protein Metnase mediates foreign DNA integration and links integration to nonhomologous end-joining repairIsolation and analysis of retroviral integration targets by solo long terminal repeat inverse PCRIntegrase-specific enhancement and suppression of retroviral DNA integration by compacted chromatin structure in vitroModeling insertional mutagenesis using gene length and expression in murine embryonic stem cells.Fidelity of target site duplication and sequence preference during integration of xenotropic murine leukemia virus-related virus.Specific insertions of zinc finger domains into Gag-Pol yield engineered retroviral vectors with selective integration propertiesSite-specific gene insertion mediated by a Cre-loxP-carrying lentiviral vector.Human immunodeficiency virus type 1 incorporated with fusion proteins consisting of integrase and the designed polydactyl zinc finger protein E2C can bias integration of viral DNA into a predetermined chromosomal region in human cellsAn amino acid in the central catalytic domain of three retroviral integrases that affects target site selection in nonviral DNA.Integration by design.Targeting HIV-1 integrase.A high-throughput method for cloning and sequencing human immunodeficiency virus type 1 integration sites.Fusion proteins consisting of human immunodeficiency virus type 1 integrase and the designed polydactyl zinc finger protein E2C direct integration of viral DNA into specific sitesIdentifying and characterizing a functional HIV-1 reverse transcriptase-binding site on integrase.Genome-wide analyses of avian sarcoma virus integration sites.Analysis of wild-type and mutant SL3-3 murine leukemia virus insertions in the c-myc promoter during lymphomagenesis reveals target site hot spots, virus-dependent patterns, and frequent error-prone gap repair.Role of the nonspecific DNA-binding region and alpha helices within the core domain of retroviral integrase in selecting target DNA sites for integration.Proviruses selected for high and stable expression of transduced genes accumulate in broadly transcribed genome areas.Preferential integration of human immunodeficiency virus type 1 into genes, cytogenetic R bands and GC-rich DNA regions: insight from the human genome sequence.
P2860
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P2860
Molecular genetics and target site specificity of retroviral integration.
description
2001 nî lūn-bûn
@nan
2001 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Molecular genetics and target site specificity of retroviral integration.
@ast
Molecular genetics and target site specificity of retroviral integration.
@en
Molecular genetics and target site specificity of retroviral integration.
@nl
type
label
Molecular genetics and target site specificity of retroviral integration.
@ast
Molecular genetics and target site specificity of retroviral integration.
@en
Molecular genetics and target site specificity of retroviral integration.
@nl
prefLabel
Molecular genetics and target site specificity of retroviral integration.
@ast
Molecular genetics and target site specificity of retroviral integration.
@en
Molecular genetics and target site specificity of retroviral integration.
@nl
P2093
P1433
P1476
Molecular genetics and target site specificity of retroviral integration.
@en
P2093
P356
10.1016/S0065-2660(01)43003-3
P577
2001-01-01T00:00:00Z