Stable expression of calpain 3 from a muscle transgene in vivo: immature muscle in transgenic mice suggests a role for calpain 3 in muscle maturation.
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Endogenous Nmnat2 is an essential survival factor for maintenance of healthy axonsMultiple molecular interactions implicate the connectin/titin N2A region as a modulating scaffold for p94/calpain 3 activity in skeletal muscleSkeletal muscle-specific calpain is an intracellular Na+-dependent proteaseDown-regulation of MyoD by calpain 3 promotes generation of reserve cells in C2C12 myoblastsRbfox1 downregulation and altered calpain 3 splicing by FRG1 in a mouse model of Facioscapulohumeral muscular dystrophy (FSHD)Endogenous calpain-3 activation is primarily governed by small increases in resting cytoplasmic [Ca2+] and is not dependent on stretchMdm muscular dystrophy: interactions with calpain 3 and a novel functional role for titin's N2A domain.Myogenic stage, sarcomere length, and protease activity modulate localization of muscle-specific calpain.Predicting candidate genes based on combined network topological features: a case study in coronary artery diseaseSuppressed disassembly of autolyzing p94/CAPN3 by N2A connectin/titin in a genetic reporter system.The N- and C-terminal autolytic fragments of CAPN3/p94/calpain-3 restore proteolytic activity by intermolecular complementation.Muscle giants: molecular scaffolds in sarcomerogenesis.Sarcospan reduces dystrophic pathology: stabilization of the utrophin-glycoprotein complex.Autolytic activation of calpain 3 proteinase is facilitated by calmodulin proteinLoss of calpain-3 autocatalytic activity in LGMD2A patients with normal protein expression.Membrane Repair: Mechanisms and Pathophysiology.Regulation and physiological roles of the calpain system in muscular disordersMuscle Transcriptional Profile Based on Muscle Fiber, Mitochondrial Respiratory Activity, and Metabolic Enzymes.Calpain 3: a key regulator of the sarcomere?Calpain 3, the "gatekeeper" of proper sarcomere assembly, turnover and maintenance.Muscle-specific calpain is localized in regions near motor endplates in differentiating lobster claw musclesMitochondrial abnormalities, energy deficit and oxidative stress are features of calpain 3 deficiency in skeletal musclePhysiologic and pathophysiologic role of calpain: implications for the occurrence of atrial fibrillation.Dysferlin overexpression in skeletal muscle produces a progressive myopathy.Calpain 3 is activated through autolysis within the active site and lyses sarcomeric and sarcolemmal componentsCorrelations between clinical severity, genotype and muscle pathology in limb girdle muscular dystrophy type 2A.Structural and functional analysis of the sarcoglycan-sarcospan subcomplex.Expression of a calpastatin transgene slows muscle wasting and obviates changes in myosin isoform expression during murine muscle disuse.Reduced skeletal muscle fiber size following caloric restriction is associated with calpain-mediated proteolysis and attenuation of IGF-1 signaling.Expression of a muscle-specific, nitric oxide synthase transgene prevents muscle membrane injury and reduces muscle inflammation during modified muscle use in mice.Possible regulation of the conventional calpain system by skeletal muscle-specific calpain, p94/calpain 3.Exploiting the CRISPR/Cas9 system to study alternative splicing in vivo: application to titin.Involvement of calpains in Ca2+-induced disruption of excitation-contraction coupling in mammalian skeletal muscle fibers.Muscle-specific calpain-3 is phosphorylated in its unique insertion region for enrichment in a myofibril fraction.
P2860
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P2860
Stable expression of calpain 3 from a muscle transgene in vivo: immature muscle in transgenic mice suggests a role for calpain 3 in muscle maturation.
description
2002 nî lūn-bûn
@nan
2002 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Stable expression of calpain 3 ...... alpain 3 in muscle maturation.
@ast
Stable expression of calpain 3 ...... alpain 3 in muscle maturation.
@en
Stable expression of calpain 3 ...... alpain 3 in muscle maturation.
@nl
type
label
Stable expression of calpain 3 ...... alpain 3 in muscle maturation.
@ast
Stable expression of calpain 3 ...... alpain 3 in muscle maturation.
@en
Stable expression of calpain 3 ...... alpain 3 in muscle maturation.
@nl
prefLabel
Stable expression of calpain 3 ...... alpain 3 in muscle maturation.
@ast
Stable expression of calpain 3 ...... alpain 3 in muscle maturation.
@en
Stable expression of calpain 3 ...... alpain 3 in muscle maturation.
@nl
P2093
P2860
P356
P1476
Stable expression of calpain 3 ...... calpain 3 in muscle maturation
@en
P2093
I Dalkilic
J Chamberlain
L M Kunkel
M J Spencer
P2860
P304
P356
10.1073/PNAS.132269299
P407
P577
2002-06-19T00:00:00Z