Human chronic lymphocytic leukemia modeled in mouse by targeted TCL1 expression - Wikidata - awgldk - TriplyDB

Human chronic lymphocytic leukemia modeled in mouse by targeted TCL1 expression

Human chronic lymphocytic leukemia modeled in mouse by targeted TCL1 expression

http://www.wikidata.org/entity/Q34068006

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Dysregulated TCL1 promotes multiple classes of mature B cell lymphoma.13q14 deletions in CLL involve cooperating tumor suppressors MicroRNAs in mouse models of lymphoid malignancies Murine models of chronic lymphocytic leukaemia: role of microRNA-16 in the New Zealand Black mouse model Epigenetic changes during disease progression in a murine model of human chronic lymphocytic leukemia Abnormal microRNA-16 locus with synteny to human 13q14 linked to CLL in NZB mice Aberrant Promoter Hypomethylation in CLL: Does It Matter for Disease Development?Regulatory Role of IL-1R8 in Immunity and Disease TCL1 transgenic mouse model as a tool for the study of therapeutic targets and microenvironment in human B-cell chronic lymphocytic leukemia The analysis of clonal expansions in normal and autoimmune B cell repertoires Signal transduction in the chronic leukemias: implications for targeted therapies Animal models of leukemia: any closer to the real thing?Next-generation XPO1 inhibitor shows improved efficacy and in vivo tolerability in hematological malignancies Murine Models of Splenic Marginal Zone Lymphoma: A Role for Cav1?Identifying High-Risk Chronic Lymphocytic Leukemia: A Pathogenesis-Oriented Appraisal of Prognostic and Predictive Factors in Patients Treated with Chemotherapy with or without Immunotherapy Regulatory B10 cell development and function Genomic and epigenomic heterogeneity in chronic lymphocytic leukemia Sp1 transactivation of the TCL1 oncogene FCRL5 exerts binary and compartment-specific influence on innate-like B-cell receptor signaling TCL1 participates in early embryonic development and is overexpressed in human seminomas The novel deacetylase inhibitor AR-42 demonstrates pre-clinical activity in B-cell malignancies in vitro and in vivo Pre-B cell proliferation and lymphoblastic leukemia/high-grade lymphoma in E(mu)-miR155 transgenic mice Clustering of Expression Data in Chronic Lymphocytic Leukemia Reveals New Molecular Subdivisions.Tcl1 interacts with Atm and enhances NF-κB activation in hematologic malignancies.Cellular origin(s) of chronic lymphocytic leukemia: cautionary notes and additional considerations and possibilities.Proteomic-based identification of maternal proteins in mature mouse oocytes Gene expression factors as predictors of genetic risk and survival in chronic lymphocytic leukemia Using Murine Models to Investigate Tumor-Lymphoid Interactions: Spotlight on Chronic Lymphocytic Leukemia and Angioimmunoblastic T-Cell Lymphoma.Tumorigenesis promotes Mdm4-S overexpression.B10 cell regulation of health and disease.PI3Kδ inhibition elicits anti-leukemic effects through Bim-dependent apoptosis Chronic lymphocytic leukemia cells induce changes in gene expression of CD4 and CD8 T cells.Epigenetic alterations in a murine model for chronic lymphocytic leukemia.The CD37-targeted antibody-drug conjugate IMGN529 is highly active against human CLL and in a novel CD37 transgenic murine leukemia model Cytokine-driven loss of plasmacytoid dendritic cell function in chronic lymphocytic leukemia Induction of p53-mediated transcription and apoptosis by exportin-1 (XPO1) inhibition in mantle cell lymphoma.Potential of plant-derived natural products in the treatment of leukemia and lymphoma Chronic lymphocytic leukemia modeled in mouse by targeted miR-29 expression.Chronic lymphocytic leukemia disease progression is accelerated by APRIL-TACI interaction in the TCL1 transgenic mouse model.Modeling tumor-host interactions of chronic lymphocytic leukemia in xenografted mice to study tumor biology and evaluate targeted therapy

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P2860

Human chronic lymphocytic leukemia modeled in mouse by targeted TCL1 expression

http://www.wikidata.org/entity/Q34068006

description

2002 nî lūn-bûn

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2002 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2002 թվականի մայիսին հրատարակված գիտական հոդված

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2002年の論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年论文

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name

Human chronic lymphocytic leukemia modeled in mouse by targeted TCL1 expression

@ast

Human chronic lymphocytic leukemia modeled in mouse by targeted TCL1 expression

@en

Human chronic lymphocytic leukemia modeled in mouse by targeted TCL1 expression

@nl

type

label

Human chronic lymphocytic leukemia modeled in mouse by targeted TCL1 expression

@ast

Human chronic lymphocytic leukemia modeled in mouse by targeted TCL1 expression

@en

Human chronic lymphocytic leukemia modeled in mouse by targeted TCL1 expression

@nl

prefLabel

Human chronic lymphocytic leukemia modeled in mouse by targeted TCL1 expression

@ast

Human chronic lymphocytic leukemia modeled in mouse by targeted TCL1 expression

@en

Human chronic lymphocytic leukemia modeled in mouse by targeted TCL1 expression

@nl

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Human chronic lymphocytic leukemia modeled in mouse by targeted TCL1 expression

@en

P2093

Anatoliy Koval

http://www.w3.org/2001/XMLSchema#string

Eric S Martin

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Giandomenico Russo

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Richard R Hardy

http://www.w3.org/2001/XMLSchema#string

Roberta Bichi

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Rossano Cesari

http://www.w3.org/2001/XMLSchema#string

Susan A Shinton

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P2860

Identification of the TCL1 gene involved in T-cell malignancies

Origin of murine B cell lineages

Expression of the TCL1 gene at 14q32 in B-cell malignancies but not in adult T-cell leukemia

Cancer statistics, 1998.

Activated Ras signals developmental progression of recombinase-activating gene (RAG)-deficient pro-B lymphocytes.

Deregulated expression of TCL1 causes T cell leukemia in mice

Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow

Human c-myc onc gene is located on the region of chromosome 8 that is translocated in Burkitt lymphoma cells.

Expression of Lyt-1 antigen on certain murine B cell lymphomas.

The regulated expression of B lineage associated genes during B cell differentiation in bone marrow and fetal liver

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6955-6960

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scholarly article

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10.1073/PNAS.102181599

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P433

10

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99

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Carlo Maria Croce

George A. Calin

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2002-05-01T00:00:00Z

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11360949

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12011454

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124510

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