E3 ubiquitin ligase Mule ubiquitinates Miz1 and is required for TNFalpha-induced JNK activation. - Wikidata - awgldk - TriplyDB

E3 ubiquitin ligase Mule ubiquitinates Miz1 and is required for TNFalpha-induced JNK activation.

E3 ubiquitin ligase Mule ubiquitinates Miz1 and is required for TNFalpha-induced JNK activation.

http://www.wikidata.org/entity/Q34068131

about

Miz1 deficiency in the mammary gland causes a lactation defect by attenuated Stat5 expression and phosphorylation Tumor cell-specific inhibition of MYC function using small molecule inhibitors of the HUWE1 ubiquitin ligase Tipping the MYC-MIZ1 balance: targeting the HUWE1 ubiquitin ligase selectively blocks MYC-activated genes.Site-specific ubiquitination is required for relieving the transcription factor Miz1-mediated suppression on TNF-α-induced JNK activation and inflammation.DNA damage-induced activation of CUL4B targets HUWE1 for proteasomal degradation.Stress-induced phosphorylation and proteasomal degradation of mitofusin 2 facilitates mitochondrial fragmentation and apoptosis.Syk-mediated tyrosine phosphorylation of mule promotes TNF-induced JNK activation and cell death Suppression of inflammation and acute lung injury by Miz1 via repression of C/EBP-δ.HUWE1 mutations in Juberg-Marsidi and Brooks syndromes: the results of an X-chromosome exome sequencing study.Mule/Huwe1/Arf-BP1 suppresses Ras-driven tumorigenesis by preventing c-Myc/Miz1-mediated down-regulation of p21 and p15 The emerging role of the ubiquitin proteasome in pulmonary biology and disease.Biphasic influence of Miz1 on neural crest development by regulating cell survival and apical adhesion complex formation in the developing neural tube The emerging role of Mule and ARF in the regulation of base excision repair.Myc-interacting zinc-finger protein 1 positively regulates Wnt signalling by protecting Dishevelled from Dapper1-mediated degradation.Mule determines the apoptotic response to HDAC inhibitors by targeted ubiquitination and destruction of HDAC2.A conformational switch regulates the ubiquitin ligase HUWE1.Increased expression of Myc-interacting zinc finger protein 1 in APP/PS1 mice.Decreased MIZ1 Expression in Severe Experimental Acute Pancreatitis: A Rat Study.Ubiquitination by HUWE1 in tumorigenesis and beyond

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P2860

E3 ubiquitin ligase Mule ubiquitinates Miz1 and is required for TNFalpha-induced JNK activation.

http://www.wikidata.org/entity/Q34068131

description

2010 nî lūn-bûn

@nan

2010 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հուլիսին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

E3 ubiquitin ligase Mule ubiqu ...... Falpha-induced JNK activation.

@ast

E3 ubiquitin ligase Mule ubiqu ...... Falpha-induced JNK activation.

@en

E3 ubiquitin ligase Mule ubiqu ...... Falpha-induced JNK activation.

@nl

type

label

E3 ubiquitin ligase Mule ubiqu ...... Falpha-induced JNK activation.

@ast

E3 ubiquitin ligase Mule ubiqu ...... Falpha-induced JNK activation.

@en

E3 ubiquitin ligase Mule ubiqu ...... Falpha-induced JNK activation.

@nl

prefLabel

E3 ubiquitin ligase Mule ubiqu ...... Falpha-induced JNK activation.

@ast

E3 ubiquitin ligase Mule ubiqu ...... Falpha-induced JNK activation.

@en

E3 ubiquitin ligase Mule ubiqu ...... Falpha-induced JNK activation.

@nl

P1433

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P2860

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P304

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P5875

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P921

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P932

Q34068131-00305B96-9256-4066-A8A8-A3554B26D3FA

P356

PNAS.0913690107

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

E3 ubiquitin ligase Mule ubiqu ...... Falpha-induced JNK activation.

@en

P2093

Chaozheng Zhang

http://www.w3.org/2001/XMLSchema#string

HanhChi Do

http://www.w3.org/2001/XMLSchema#string

Jacob I Sznajder

http://www.w3.org/2001/XMLSchema#string

Jing Liu

http://www.w3.org/2001/XMLSchema#string

Laura A Dada

http://www.w3.org/2001/XMLSchema#string

Xinyuan Liu

http://www.w3.org/2001/XMLSchema#string

Xuejun Tian

http://www.w3.org/2001/XMLSchema#string

Yi Yang

http://www.w3.org/2001/XMLSchema#string

P2860

Characterization of E3Histone, a novel testis ubiquitin protein ligase which ubiquitinates histones.

ARF-BP1/Mule is a critical mediator of the ARF tumor suppressor

Mule/ARF-BP1, a BH3-only E3 ubiquitin ligase, catalyzes the polyubiquitination of Mcl-1 and regulates apoptosis

Zbtb4 represses transcription of P21CIP1 and controls the cellular response to p53 activation

Ubiquitin ligase ARF-BP1/Mule modulates base excision repair

Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes

The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells

TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways

Miz1 and HectH9 regulate the stability of the checkpoint protein, TopBP1

An alternative pathway for gene regulation by Myc

P304

13444-13449

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1073/PNAS.0913690107

http://www.w3.org/2001/XMLSchema#string

P407

P433

30

http://www.w3.org/2001/XMLSchema#string

P478

107

http://www.w3.org/2001/XMLSchema#string

P577

2010-07-12T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

45167356

http://www.w3.org/2001/XMLSchema#string

P698

20624960

http://www.w3.org/2001/XMLSchema#string

P921

protein ubiquitination

P932

2922175

http://www.w3.org/2001/XMLSchema#string