Galpha(i1) and Galpha(i3) are required for epidermal growth factor-mediated activation of the Akt-mTORC1 pathway - Wikidata - awgldk - TriplyDB

Galpha(i1) and Galpha(i3) are required for epidermal growth factor-mediated activation of the Akt-mTORC1 pathway

Galpha(i1) and Galpha(i3) are required for epidermal growth factor-mediated activation of the Akt-mTORC1 pathway

http://www.wikidata.org/entity/Q34068730

about

RGS14 at the interface of hippocampal signaling and synaptic plasticity Osteopontin (OPN) is an important protein to mediate improvements in the biocompatibility of C ion-implanted silicone rubber Gαi3 nuclear translocation causes irradiation resistance in human glioma cells.Implications of non-canonical G-protein signaling for the immune system Heterotrimeric G protein signaling outside the realm of seven transmembrane domain receptors Squamosamide derivative FLZ protects retinal pigment epithelium cells from oxidative stress through activation of epidermal growth factor receptor (EGFR)-AKT signaling.A GDI (AGS3) and a GEF (GIV) regulate autophagy by balancing G protein activity and growth factor signals Gab1 is essential for membrane translocation, activity and integrity of mTORCs after EGF stimulation in urothelial cell carcinoma.Suberoylanilide hydroxamic acid, an inhibitor of histone deacetylase, suppresses vasculogenic mimicry and proliferation of highly aggressive pancreatic cancer PaTu8988 cells Gαi1 and Gαi3 regulate macrophage polarization by forming a complex containing CD14 and Gab1.Determinant role for the gep oncogenes, Gα12/13, in ovarian cancer cell proliferation and xenograft tumor growth.Gab3 overexpression in human glioma mediates Akt activation and tumor cell proliferation.The roles of G proteins in the activation of TRPC4 and TRPC5 transient receptor potential channels.Assembly and function of the regulator of G protein signaling 14 (RGS14)·H-Ras signaling complex in live cells are regulated by Gαi1 and Gαi-linked G protein-coupled receptors.Epidermal growth factor regulates hematopoietic regeneration after radiation injury Blunted apoptosis of erythrocytes in mice deficient in the heterotrimeric G-protein subunit Gαi2 A novel noncanonical signaling pathway for the μ-opioid receptor.G(i)α proteins exhibit functional differences in the activation of ERK1/2, Akt and mTORC1 by growth factors in normal and breast cancer cells.MHY1485 ameliorates UV-induced skin cell damages via activating mTOR-Nrf2 signaling.Novel approaches to vitiligo treatment via modulation of mTOR and NF-κB pathways in human skin melanocytes.Signal protein-derived peptides as functional probes and regulators of intracellular signaling.GIV/Girdin is a rheostat that fine-tunes growth factor signals during tumor progression.Berberine-induced apoptotic and autophagic death of HepG2 cells requires AMPK activation.Activation of Akt by SC79 protects myocardiocytes from oxygen and glucose deprivation (OGD)/re-oxygenation.The essential role of Giα2 in prostate cancer cell migration.TBX2 over-expression promotes nasopharyngeal cancer cell proliferation and invasion.GSK1059615 kills head and neck squamous cell carcinoma cells possibly via activating mitochondrial programmed necrosis pathway.Necrostatin-1 inhibits Hmgb1-IL-23/IL-17 pathway and attenuates cardiac ischemia reperfusion injury.Ginseng Rh2 protects endometrial cells from oxygen glucose deprivation/re-oxygenation.Epiregulin and EGFR interactions are involved in pain processing.Targeted reduction of the EGFR protein, but not inhibition of its kinase activity, induces mitophagy and death of cancer cells through activation of mTORC2 and Akt.Membrane Recruitment of the Non-receptor Protein GIV/Girdin (Gα-interacting, Vesicle-associated Protein/Girdin) Is Sufficient for Activating Heterotrimeric G Protein Signaling.Antidepression action of BDNF requires and is mimicked by Gαi1/3 expression in the hippocampus.Inhibition of RIP1-dependent necrosis prevents adverse cardiac remodeling after myocardial ischemia-reperfusion in vivo.Gαi1 and Gαi3mediate VEGF-induced VEGFR2 endocytosis, signaling and angiogenesis

P2860

Q27021103-93AB3E1B-778E-4CBD-9A90-22DC18B4DA0C Q28539498-4246A819-0D71-4543-BBF8-E9CB49B5229F Q33798731-22F86397-216D-489A-A08D-2EBF9657FC4A Q33978840-5EA8FA2F-53F9-4482-83B7-AC555FCD53FC Q34028196-3BAC6BF3-A79D-4415-9969-1A859489DE21 Q34486928-FBF9792C-6962-4160-88FD-E08069E52B6C Q34611677-7916DB9D-D73C-4CE6-B050-6457A8C51106 Q35176340-639F6235-3FF3-42D2-B419-87797B01AFAD Q35179190-39CD1117-817E-4CA5-9C73-9C96CC37CFDA Q35485252-3A52241B-1300-446D-A6B8-0CEC774F8C01 Q36075415-A3574E7D-8242-4D47-AEA0-AA201566870A Q36307539-FBD20C51-D9DD-43FC-8A9A-2A58835C5B21 Q36430231-F009EC10-13D7-4E09-BE9D-BD3A779FA4AF Q36579634-FEF3C749-40CB-4B44-9776-F3967CD84E71 Q36674536-C4F35CBE-2430-463E-9AE1-A53EE3D99542 Q37157380-8738D94C-D1CA-44C0-B0AF-8D9ADC390938 Q37325629-44761452-A5F6-45DF-B68D-C6A7B9ABDA06 Q37607405-E1B6A5D6-C411-41F5-BD61-472E36BBE005 Q37706491-C69F7475-A926-495A-85DC-490FF5D7E822 Q37726250-2A92F1AA-0EA9-4F3A-BD51-5E67670E6E9F Q37982071-1FD8BDDB-04BE-438E-8E95-90FA36DC6353 Q38974569-2E6C36A7-9FA8-4A73-9209-A8CB1DC7678C Q38978483-33EA226D-B5DE-473A-8F31-20D4689644A1 Q38999390-BDBB76DC-626F-4E83-8123-3E0393C25529 Q39287870-B1057E0E-6B82-4D1B-97CA-4A2BBFC6D8A9 Q41592860-E1409073-B8B6-402F-8A5F-82533C087EFA Q41612466-AF3A72E4-41B8-44E8-83B9-CCD81AC8EEA4 Q46896240-36471D06-99E3-4FB9-B853-6B299889AF75 Q47151581-65F0AA7A-17FF-4D7A-8B1F-F29DEB73B3E8 Q47265974-14F95973-15FD-48AF-B7A1-26F365AACF98 Q47557798-E3067B9D-E96F-46C1-8E91-B3121BECB023 Q51316906-9448A3B3-67B9-4F6B-A81C-C8FACBC638B5 Q52673249-ACF14991-BE3D-42D2-BE37-C754AD31F894 Q54513464-1B185D52-30C2-43DF-AA13-110371662A68 Q57116127-8987E944-62E6-4FCB-992F-BCB501B14A2C

P2860

Galpha(i1) and Galpha(i3) are required for epidermal growth factor-mediated activation of the Akt-mTORC1 pathway

http://www.wikidata.org/entity/Q34068730

description

2009 nî lūn-bûn

@nan

2009 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

2009年の論文

@ja

2009年論文

@yue

2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

@wuu

name

Galpha(i1) and Galpha(i3) are ...... tion of the Akt-mTORC1 pathway

@ast

Galpha(i1) and Galpha(i3) are ...... tion of the Akt-mTORC1 pathway

@en

type

label

Galpha(i1) and Galpha(i3) are ...... tion of the Akt-mTORC1 pathway

@ast

Galpha(i1) and Galpha(i3) are ...... tion of the Akt-mTORC1 pathway

@en

prefLabel

Galpha(i1) and Galpha(i3) are ...... tion of the Akt-mTORC1 pathway

@ast

Galpha(i1) and Galpha(i3) are ...... tion of the Akt-mTORC1 pathway

@en

P1433

Q34068730-CAE7A384-F2E5-434A-B4DF-074B0562AF21

P1476

Q34068730-CAD5CDF1-A4DC-45D7-9359-408992426946

P2093

Q34068730-246358B4-61D2-4435-8F8D-9B629CB60DBA

Q34068730-3BBA5F17-3AF7-4772-9B07-8DF9F2D8886D

Q34068730-4847BB40-CB69-4861-9949-9B4E9DFEC948

Q34068730-7A076CFD-7905-4293-A24E-F783A570C78E

Q34068730-A6CCCC3B-777D-49E2-90C5-A2889DC121FB

Q34068730-D010C142-88B6-4364-AC16-525F8931453C

Q34068730-DBA4D054-BEA6-4D08-A7A9-A18E4D281CCB

Q34068730-F10F19D4-6660-4143-97C9-C3BADD73D079

Q34068730-F6AE677C-D396-4A6A-BEDA-C3B8907C0D12

P2860

Q34068730-0ABAF91B-B4FC-4665-A408-80980AD04F13

Q34068730-0C56C29F-E6F9-42E5-A905-C9111C08423C

Q34068730-1A12B33C-16A7-4D04-AB06-E9326BB8C657

Q34068730-1AEDF5E4-B0ED-43CF-BA34-D1FBA5A93100

Q34068730-1C1EA143-F3F4-42A3-972D-1719BCA93BBB

Q34068730-1E238673-B3CD-4246-ACBF-8D86722FC4E0

Q34068730-27DD4F2D-B109-4F6C-A5FE-1C53F6D44F16

Q34068730-2E0266A0-69A7-40EC-9868-13A2F7C71534

Q34068730-397A2197-715C-47B2-A4FE-E87AB734555B

Q34068730-40840B45-104A-4516-898F-7721A929F20A

P304

Q34068730-095EA798-2674-4472-B739-5119DB53019C

P31

Q34068730-A36390A0-5082-40AB-A73F-A5CC99490D19

P356

Q34068730-11A7094B-1F98-4740-85B9-48569B0D693D

P433

Q34068730-F4918F33-DD74-478A-BEB0-C5E25E27B33C

P478

Q34068730-E41DAB9F-D25B-41C4-82C2-E4399E4AFF4E

P577

Q34068730-0EBC6ECC-9FFA-4187-B7E8-2F0A6B52F13E

P698

Q34068730-FCBA3253-3AEC-480F-9AFE-17ED5AC16535

P932

Q34068730-DF9BCE48-B4FD-49A1-9F12-C8C7DF10B1CC

P356

SCISIGNAL.2000118

P1433

Science Signaling

P1476

Galpha(i1) and Galpha(i3) are ...... tion of the Akt-mTORC1 pathway

@en

P2093

Cong Cao

http://www.w3.org/2001/XMLSchema#string

Geng-Sheng Feng

http://www.w3.org/2001/XMLSchema#string

John Marshall

http://www.w3.org/2001/XMLSchema#string

Lutz Birnbaumer

http://www.w3.org/2001/XMLSchema#string

Meisheng Jiang

http://www.w3.org/2001/XMLSchema#string

Wen-Ming Chu

http://www.w3.org/2001/XMLSchema#string

Xuesong Huang

http://www.w3.org/2001/XMLSchema#string

Yinsheng Wan

http://www.w3.org/2001/XMLSchema#string

Yuyuan Han

http://www.w3.org/2001/XMLSchema#string

P2860

A Grb2-associated docking protein in EGF- and insulin-receptor signalling

The docking protein Gab1 is the primary mediator of EGF-stimulated activation of the PI-3K/Akt cell survival pathway

Activation of the phosphatidylinositol 3-kinase Vps34 by a G protein alpha subunit at the endosome.

The G protein subunit gene families

The role of Gab family scaffolding adapter proteins in the signal transduction of cytokine and growth factor receptors

The G protein G alpha(13) is required for growth factor-induced cell migration

Protein kinase B alpha/Akt1 regulates placental development and fetal growth

Multiple roles of the PI3K/PKB (Akt) pathway in cell cycle progression

mTOR and cancer: insights into a complex relationship

grb2 heterozygosity rescues embryonic lethality but not tumorigenesis in pten+/- mice.

P304

ra17

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1126/SCISIGNAL.2000118

http://www.w3.org/2001/XMLSchema#string

P433

68

http://www.w3.org/2001/XMLSchema#string

P478

2

http://www.w3.org/2001/XMLSchema#string

P577

2009-04-28T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

19401591

http://www.w3.org/2001/XMLSchema#string

P932

4138699

http://www.w3.org/2001/XMLSchema#string