Evaluation of adenovirus-delivered human CD59 as a potential therapy for AMD in a model of human membrane attack complex formation on murine RPE.
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Soluble CD59 expressed from an adenovirus in vivo is a potent inhibitor of complement deposition on murine liver vascular endotheliumA non membrane-targeted human soluble CD59 attenuates choroidal neovascularization in a model of age related macular degeneration.The membrane attack complex in aging human choriocapillaris: relationship to macular degeneration and choroidal thinning.Decay accelerating factor (CD55)-mediated attenuation of complement: therapeutic implications for age-related macular degeneration.Aurintricarboxylic acid inhibits complement activation, membrane attack complex, and choroidal neovascularization in a model of macular degeneration.Retinal pigment epithelial cell death by the alternative complement cascade: role of membrane regulatory proteins, calcium, PKC, and oxidative stress.A2E accumulation influences retinal microglial activation and complement regulationAdeno-associated virus mediated delivery of an engineered protein that combines the complement inhibitory properties of CD46, CD55 and CD59Drosophila GPI-mannosyltransferase 2 is required for GPI anchor attachment and surface expression of chaoptin.Mechanism of inflammation in age-related macular degenerationA Revised Hemodynamic Theory of Age-Related Macular Degeneration.Adenovirus-mediated delivery of CD46 attenuates the alternative complement pathway on RPE: implications for age-related macular degeneration.Adenovirus-mediated delivery of Factor H attenuates complement C3 induced pathology in the murine retina: a potential gene therapy for age-related macular degeneration.Polyethylene glycol (PEG)-induced mouse model of choroidal neovascularization.
P2860
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P2860
Evaluation of adenovirus-delivered human CD59 as a potential therapy for AMD in a model of human membrane attack complex formation on murine RPE.
description
2008 nî lūn-bûn
@nan
2008 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Evaluation of adenovirus-deliv ...... mplex formation on murine RPE.
@ast
Evaluation of adenovirus-deliv ...... mplex formation on murine RPE.
@en
Evaluation of adenovirus-deliv ...... mplex formation on murine RPE.
@nl
type
label
Evaluation of adenovirus-deliv ...... mplex formation on murine RPE.
@ast
Evaluation of adenovirus-deliv ...... mplex formation on murine RPE.
@en
Evaluation of adenovirus-deliv ...... mplex formation on murine RPE.
@nl
prefLabel
Evaluation of adenovirus-deliv ...... mplex formation on murine RPE.
@ast
Evaluation of adenovirus-deliv ...... mplex formation on murine RPE.
@en
Evaluation of adenovirus-deliv ...... mplex formation on murine RPE.
@nl
P2093
P2860
P356
P1476
Evaluation of adenovirus-deliv ...... mplex formation on murine RPE.
@en
P2093
Kasmir Ramo
Rajendra Kumar-Singh
Siobhan M Cashman
P2860
P304
P356
10.1167/IOVS.08-2025
P407
P577
2008-05-16T00:00:00Z