Leukocytes navigate by compass: roles of PI3Kgamma and its lipid products
about
A Dictyostelium homologue of WASP is required for polarized F-actin assembly during chemotaxisPhosphoinositide 3-kinase-mediated activation of cofilin phosphatase Slingshot and its role for insulin-induced membrane protrusionPLEKHG2 promotes heterotrimeric G protein βγ-stimulated lymphocyte migration via Rac and Cdc42 activation and actin polymerization.Spatial and temporal regulation of cofilin activity by LIM kinase and Slingshot is critical for directional cell migrationSWAP-70 identifies a transitional subset of actin filaments in motile cells.The SH2-containing inositol polyphosphate 5-phosphatase, SHIP-2, binds filamin and regulates submembraneous actinbFGF regulates PI3-kinase-Rac1-JNK pathway and promotes fibroblast migration in wound healingHow cells integrate complex stimuli: the effect of feedback from phosphoinositides and cell shape on cell polarization and motilityCell shape dynamics: from waves to migrationA mathematical model for neutrophil gradient sensing and polarizationRepurposing Treatments to Enhance Innate Immunity. Can Statins Improve Neutrophil Functions and Clinical Outcomes in COPD?Wiskott-Aldrich syndrome protein and the cytoskeletal dynamics of dendritic cellsRasC is required for optimal activation of adenylyl cyclase and Akt/PKB during aggregationAn SH2-domain-containing kinase negatively regulates the phosphatidylinositol-3 kinase pathwayPIP3, PIP2, and cell movement--similar messages, different meanings?WAVE2 is required for directed cell migration and cardiovascular developmentModulation of HeLa cells spreading by the non-receptor tyrosine kinase ACK-2.Phosphatidylinositol 3,4,5-trisphosphate localization in recycling endosomes is necessary for AP-1B-dependent sorting in polarized epithelial cellsThe role of endothelial PI3Kgamma activity in neutrophil trafficking.Neutrophils lacking phosphoinositide 3-kinase gamma show loss of directionality during N-formyl-Met-Leu-Phe-induced chemotaxisTumor suppressor PTEN is a physiologic suppressor of chemoattractant-mediated neutrophil functionsDynamic shifts in LFA-1 affinity regulate neutrophil rolling, arrest, and transmigration on inflamed endothelium.Optimization of WAVE2 complex-induced actin polymerization by membrane-bound IRSp53, PIP(3), and Rac.RACK1 regulates directional cell migration by acting on G betagamma at the interface with its effectors PLC beta and PI3K gamma.Immunostaining evidence for PI(4,5)P2 localization at the leading edge of chemoattractant-stimulated HL-60 cells.Conformational switching in ezrin regulates morphological and cytoskeletal changes required for B cell chemotaxisDelineating the core regulatory elements crucial for directed cell migration by examining folic-acid-mediated responsesOptical control demonstrates switch-like PIP3 dynamics underlying the initiation of immune cell migration.Mammalian target of rapamycin and Rictor control neutrophil chemotaxis by regulating Rac/Cdc42 activity and the actin cytoskeletonHomer3 regulates the establishment of neutrophil polarityQuantitative imaging of single live cells reveals spatiotemporal dynamics of multistep signaling events of chemoattractant gradient sensing in DictyosteliumDirect binding of a fragment of the Wiskott-Aldrich syndrome protein to the C-terminal end of the anaphylatoxin C5a receptor.Involvement of Cdc42 and Rac small G proteins in invadopodia formation of RPMI7951 cells.The unique N-terminus of R-ras is required for Rac activation and precise regulation of cell migration.Vav activation and function as a rac guanine nucleotide exchange factor in macrophage colony-stimulating factor-induced macrophage chemotaxis.Alteration of phosphatidylinositol 3-kinase cascade in the multilobulated nuclear formation of adult T cell leukemia/lymphoma (ATLL)The signaling mechanisms underlying cell polarity and chemotaxisModels of eukaryotic gradient sensing: application to chemotaxis of amoebae and neutrophils.The C terminus of mouse monocyte chemoattractant protein 1 (MCP1) mediates MCP1 dimerization while blocking its chemotactic potency.Distinguishing modes of eukaryotic gradient sensing.
P2860
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P2860
Leukocytes navigate by compass: roles of PI3Kgamma and its lipid products
description
2000 nî lūn-bûn
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2000 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի նոյեմբերին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Leukocytes navigate by compass: roles of PI3Kgamma and its lipid products
@ast
Leukocytes navigate by compass: roles of PI3Kgamma and its lipid products
@en
Leukocytes navigate by compass: roles of PI3Kgamma and its lipid products
@nl
type
label
Leukocytes navigate by compass: roles of PI3Kgamma and its lipid products
@ast
Leukocytes navigate by compass: roles of PI3Kgamma and its lipid products
@en
Leukocytes navigate by compass: roles of PI3Kgamma and its lipid products
@nl
prefLabel
Leukocytes navigate by compass: roles of PI3Kgamma and its lipid products
@ast
Leukocytes navigate by compass: roles of PI3Kgamma and its lipid products
@en
Leukocytes navigate by compass: roles of PI3Kgamma and its lipid products
@nl
P2093
P2860
P1476
Leukocytes navigate by compass: roles of PI3Kgamma and its lipid products
@en
P2093
P2860
P304
P356
10.1016/S0962-8924(00)01841-9
P577
2000-11-01T00:00:00Z