CRISPR/Cas9-mediated gene knock-down in post-mitotic neurons.
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CRISPR/Cas9: Implications for Modeling and Therapy of Neurodegenerative DiseasesGenome Engineering with TALE and CRISPR Systems in NeuroscienceApplications of CRISPR-Cas systems in neuroscienceFrom Gene Targeting to Genome Editing: Transgenic animals applications and beyondCRISPR/Cas9: a powerful genetic engineering tool for establishing large animal models of neurodegenerative diseasesEditing the Neuronal Genome: a CRISPR View of Chromatin Regulation in Neuronal Development, Function, and PlasticityApplications of CRISPR/Cas9 for Gene Editing in Hereditary Movement DisordersSomatic Mutations in TSC1 and TSC2 Cause Focal Cortical Dysplasia.N-terminal Huntingtin Knock-In Mice: Implications of Removing the N-terminal Region of Huntingtin for Therapy.CRISPR/Cas9-mediated gene knockout in the mouse brain using in utero electroporationFoxp1 regulates cortical radial migration and neuronal morphogenesis in developing cerebral cortex.Tracking and transforming neocortical progenitors by CRISPR/Cas9 gene targeting and piggyBac transposase lineage labeling.High-Throughput, High-Resolution Mapping of Protein Localization in Mammalian Brain by In Vivo Genome Editing.hPaf1/PD2 interacts with OCT3/4 to promote self-renewal of ovarian cancer stem cells.CRISPR/Cas9-induced disruption of gene expression in mouse embryonic brain and single neural stem cells in vivo.Genome Editing Reveals Glioblastoma Addiction to MicroRNA-10b.The application of CRISPR technology to high content screening in primary neurons.Cell-Specific Targeting of Genetically Encoded Tools for Neuroscience.Use of CRISPR/Cas9 to model brain diseases.CRISPR/Cas9 system-mediated impairment of synaptobrevin/VAMP function in postmitotic hippocampal neurons.Immunocytochemistry and fluorescence imaging efficiently identify individual neurons with CRISPR/Cas9-mediated gene disruption in primary cortical cultures.Developing a de novo targeted knock-in method based on in utero electroporation into the mammalian brain.Fluorescent protein tagging of endogenous protein in brain neurons using CRISPR/Cas9-mediated knock-in and in utero electroporation techniques.Somatostatin and parvalbumin inhibitory synapses onto hippocampal pyramidal neurons are regulated by distinct mechanisms.Beyond editing to writing large genomes.Critical roles of αII spectrin in brain development and epileptic encephalopathy.Combination of the clustered regularly interspaced short palindromic repeats (CRISPR)-associated 9 technique with the piggybac transposon system for mouse in utero electroporation to study cortical development.The prospects of CRISPR-based genome engineering in the treatment of neurodegenerative disorders.CRISPR-Cas9-mediated genome editing in one blastomere of two-cell embryos reveals a novel Tet3 function in regulating neocortical development.In vivo genome editing thrives with diversified CRISPR technologies.Applications of CRISPR/Cas9 in the Mammalian Central Nervous System.Tissue- and time-directed electroporation of CAS9 protein-gRNA complexes in vivo yields efficient multigene knockout for studying gene function in regeneration.Dnmt3a in the dorsal dentate gyrus is a key regulator of fear renewal.Unraveling of Central Nervous System Disease Mechanisms Using CRISPR Genome Manipulation.In vivo methods for acute modulation of gene expression in the central nervous system
P2860
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P2860
CRISPR/Cas9-mediated gene knock-down in post-mitotic neurons.
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2014 nî lūn-bûn
@nan
2014 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2014年の論文
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2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
CRISPR/Cas9-mediated gene knock-down in post-mitotic neurons.
@ast
CRISPR/Cas9-mediated gene knock-down in post-mitotic neurons.
@en
CRISPR/Cas9-mediated gene knock-down in post-mitotic neurons.
@nl
type
label
CRISPR/Cas9-mediated gene knock-down in post-mitotic neurons.
@ast
CRISPR/Cas9-mediated gene knock-down in post-mitotic neurons.
@en
CRISPR/Cas9-mediated gene knock-down in post-mitotic neurons.
@nl
prefLabel
CRISPR/Cas9-mediated gene knock-down in post-mitotic neurons.
@ast
CRISPR/Cas9-mediated gene knock-down in post-mitotic neurons.
@en
CRISPR/Cas9-mediated gene knock-down in post-mitotic neurons.
@nl
P2093
P2860
P1433
P1476
CRISPR/Cas9-mediated gene knock-down in post-mitotic neurons.
@en
P2093
Adam J Granger
Bernardo L Sabatini
Christoph Straub
Jessica L Saulnier
P2860
P304
P356
10.1371/JOURNAL.PONE.0105584
P407
P577
2014-08-20T00:00:00Z