Chronic antigen stimulation alone is sufficient to drive CD8+ T cell exhaustion - Wikidata - awgldk - TriplyDB

Chronic antigen stimulation alone is sufficient to drive CD8+ T cell exhaustion

Chronic antigen stimulation alone is sufficient to drive CD8+ T cell exhaustion

http://www.wikidata.org/entity/Q34072842

about

Targeting Transcriptional Regulators of CD8+ T Cell Dysfunction to Boost Anti-Tumor Immunity Molecular and cellular insights into T cell exhaustion Cytokine production and dysregulation in HIV pathogenesis: lessons for development of therapeutics and vaccines Biopolymer encapsulated live influenza virus as a universal CD8+ T cell vaccine against influenza virus.Influenza-specific T cells from older people are enriched in the late effector subset and their presence inversely correlates with vaccine response.Increased T-bet is associated with senescence of influenza virus-specific CD8 T cells in aged humans.CD8 cells of patients with diffuse cutaneous leishmaniasis display functional exhaustion: the latter is reversed, in vitro, by TLR2 agonists.Protective immunity against hepatitis C: many shades of gray.PD-1 regulates T cell proliferation in a tissue and subset-specific manner during normal mouse pregnancy Opposing positive and negative regulation of T cell activity during viral persistence.Role of antigen persistence and dose for CD4+ T-cell exhaustion and recovery.Immunity to cytomegalovirus in early life.Attrition of T-cell functions and simultaneous upregulation of inhibitory markers correspond with the waning of BCG-induced protection against tuberculosis in mice.Cell-intrinsic transforming growth factor-beta signaling mediates virus-specific CD8+ T cell deletion and viral persistence in vivo Endogenous T cell responses to antigens expressed in lung adenocarcinomas delay malignant tumor progression.CD4+ T cells inhibit the neu-specific CD8+ T-cell exhaustion during the priming phase of immune responses against breast cancer T cell exhaustion during persistent viral infections.Overcoming memory T-cell responses for induction of delayed tolerance in nonhuman primates.Pathogenesis of chronic viral hepatitis: differential roles of T cells and NK cells Viral acute lower respiratory infections impair CD8+ T cells through PD-1 Elevated Expression of CD160 and 2B4 Defines a Cytolytic HIV-Specific CD8+ T-Cell Population in Elite Controllers.Chronic inflammation and aging: DNA damage tips the balance.Cell-intrinsic abrogation of TGF-β signaling delays but does not prevent dysfunction of self/tumor-specific CD8 T cells in a murine model of autochthonous prostate cancer Programmed death 1 protects from fatal circulatory failure during systemic virus infection of mice.The expression of programmed death-1 in circulating CD4+ and CD8+ T cells during hepatitis B virus infection progression and its correlation with clinical baseline characteristics.Costimulation signals for memory CD8+ T cells during viral infections.Tumor necrosis factor receptor/tumor necrosis factor family members in antiviral CD8 T-cell immunity.Chikungunya virus: host pathogen interaction.Adjunct immunotherapies for tuberculosis.Suppression of Glut1 and Glucose Metabolism by Decreased Akt/mTORC1 Signaling Drives T Cell Impairment in B Cell Leukemia.Recent trends on hydrogel based drug delivery systems for infectious diseases Immune checkpoints and their inhibition in cancer and infectious diseases.Immune regulation in chronic hepatitis C virus infection.Co-inhibitory blockade while preserving tolerance: checkpoint inhibitors for glioblastoma.Mini-intronic plasmid vaccination elicits tolerant LAG3+ CD8+ T cells and inferior antitumor responses.Iatrogenic immunosuppression and risk of non-Hodgkin lymphoma in solid organ transplantation: A population-based cohort study in Australia.TCR independent suppression of CD8(+) T cell cytokine production mediated by IFNγ in vivo.Superantigen-Producing Staphylococcus aureus Elicits Systemic Immune Activation in a Murine Wound Colonization Model.Telomere Dynamics in Immune Senescence and Exhaustion Triggered by Chronic Viral Infection.Editorial: Profiling senescent influenza-specific T cells in the elderly.

P2860

Q26782201-41B09389-6B7C-4157-8632-55725E10E6E0 Q26800047-7616C5D1-FA08-4D92-B44C-A200E5D32D7B Q26827712-72A4C8DC-B385-4856-A088-D2F5B9729AF5 Q30395580-531F6D06-D97C-45E3-92CA-6AF91245E9E6 Q31030019-6BB0AB5F-262D-4874-BA42-A3C94CBD99C8 Q33732335-9CF171F1-E22E-4457-B1EC-11C967FACAE3 Q33745224-EB8AE263-BBEF-493F-8745-EC10418FDDA5 Q33759224-30186CCF-0117-4EE8-917A-2B78133C5C28 Q33893319-42755484-632C-48DC-B35C-655DD72B5FE6 Q33938039-D82BD8CC-89E4-4D25-9F89-FF9E36370755 Q34377134-D8F171BE-604C-4B62-AD6F-FBC272D29215 Q34426299-C6227B61-9D8C-4AB8-9A20-D84863622C50 Q34566311-9CB6736E-4D90-4DFD-9F0B-052098586D57 Q34577200-217FCCDE-6044-46A2-8969-1A7F11474FE5 Q34755544-5FB591F1-7B3A-4E78-A286-75B282E950D7 Q34905454-1AD6E745-0874-4CB2-917E-41BCECED5649 Q35582265-67DCBFE9-93CD-42BF-A2A1-017F369456B6 Q35714039-4B8684D8-7E34-435C-AA5A-178440194EA8 Q35786326-FA298C3D-3438-47FA-B5EB-47C052A2105A Q36129102-4D04B3B3-096B-4AF7-9E7C-73955E6D010D Q36148988-FBB1B196-E7A5-42A2-9691-82F640DDB30E Q36176981-6FB6CF93-D34D-4B45-916A-EAB27AE47515 Q36303665-7D9CD6A8-D972-4E3A-839A-4EB915B14A19 Q36478253-BFE7F562-CCC8-4F52-B53C-B61530D50FD8 Q37660410-CC169595-74EA-4832-B2E0-75FC0B1E3CFF Q37685171-7DAAE4A6-EF87-4B88-95E3-9463E0476503 Q37727208-0F21A3DF-724F-4673-9967-C08E9E0E8F01 Q37853934-B7080981-4AEC-4708-A2DE-66A3A877E164 Q37998000-8D5250F6-BFA8-448B-8720-C282A9D1B783 Q38752567-52A1AF30-DACB-4949-8857-2F6D1499E05E Q38810357-3F727AE2-9412-4402-902C-A8038BC39139 Q38845026-9FA0F3FA-B745-4FBE-8A28-D475C74EC7BD Q38902559-C93FEEFA-EC46-4BA3-9309-72D337F91BCE Q39160992-AA3A2C9A-FBF1-49BB-81AE-268474CAA82B Q39181825-5B8688ED-79C9-40FC-A1BF-2C1095B0AEC3 Q39803518-DA276187-83F1-42B4-B495-3EAB0B98E9C8 Q40562140-62AD1320-73DD-4853-8525-3224B519D565 Q40870222-9D507114-1C7B-4CB5-9B3B-072E361DE675 Q41923721-4ED106C5-D585-4365-AF6B-341CAB6634FF Q43612460-FDA3E49F-0AED-4429-8DA6-556642F4B435

P2860

Chronic antigen stimulation alone is sufficient to drive CD8+ T cell exhaustion

http://www.wikidata.org/entity/Q34072842

description

2009 nî lūn-bûn

@nan

2009 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի հունիսին հրատարակված գիտական հոդված

@hy

2009年の論文

@ja

2009年論文

@yue

2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

@wuu

name

Chronic antigen stimulation alone is sufficient to drive CD8+ T cell exhaustion

@ast

Chronic antigen stimulation alone is sufficient to drive CD8+ T cell exhaustion

@en

Chronic antigen stimulation alone is sufficient to drive CD8+ T cell exhaustion

@nl

type

label

Chronic antigen stimulation alone is sufficient to drive CD8+ T cell exhaustion

@ast

Chronic antigen stimulation alone is sufficient to drive CD8+ T cell exhaustion

@en

Chronic antigen stimulation alone is sufficient to drive CD8+ T cell exhaustion

@nl

prefLabel

Chronic antigen stimulation alone is sufficient to drive CD8+ T cell exhaustion

@ast

Chronic antigen stimulation alone is sufficient to drive CD8+ T cell exhaustion

@en

Chronic antigen stimulation alone is sufficient to drive CD8+ T cell exhaustion

@nl

P1433

Q34072842-420B40EA-4342-4F49-9C47-405403D1BAE2

P1476

Q34072842-D3599E25-22A4-43F9-A12E-88B9B886DAD8

P2093

Q34072842-0382DA59-E296-448C-A625-FA851722F9EB

Q34072842-3FB8D22E-3F13-42EB-9F81-481A97644523

Q34072842-507B1F3E-FD08-4FD6-8E31-00603A840622

Q34072842-6220511A-5240-438B-9D47-11EDD861BA3E

Q34072842-939A7755-204B-40F6-932B-6E66743CCB6D

P2860

Q34072842-008D3601-BD37-401A-A561-8625BFBC5BE8

Q34072842-02AFFD99-9AF5-4C0E-B734-A14EB93FBA1F

Q34072842-06CB0C18-9BF9-4598-98E2-F2A4A3DD5771

Q34072842-0A6D3F5C-5CFB-4676-B4A3-BB48074047BD

Q34072842-0D5E8579-40F0-47DC-A36C-67B9A9B7B019

Q34072842-1065B383-D648-4601-BA77-5605204640E2

Q34072842-194CD739-F221-471E-805B-E021BC45763E

Q34072842-2030BF97-63E7-4D9A-98B2-2A6233EE73D4

Q34072842-2666A582-16B9-4390-9803-36824292F9C6

Q34072842-27808E36-CF9C-495F-A7DE-43F998B55F3B

P304

Q34072842-4D4FD93E-2B61-4768-A761-5653527D8887

P31

Q34072842-38951A7C-D18B-41BF-9B47-AF5C80A9E9B1

P356

Q34072842-9772D956-7626-4B5E-9586-111591896A28

P407

Q34072842-91745BE7-B96A-4B53-A0B4-DB797997E4CE

P433

Q34072842-BD89ADC9-476D-480E-B00B-35022D6CA827

P478

Q34072842-3E7645F2-0F2C-4B81-8CE2-46646DB81DD2

P577

Q34072842-327A36B9-0293-4C82-B232-A94701EA7115

P5875

Q34072842-805E5BA8-7C2B-4258-8A3D-DCE70BEA3E08

P698

Q34072842-C55B49A2-76D8-4420-B12D-B5BECC7F2D0A

P932

Q34072842-9CE85335-67FD-4235-99AE-F702E410A362

P356

JIMMUNOL.0800997

P1433

Journal of Immunology

P1476

Chronic antigen stimulation alone is sufficient to drive CD8+ T cell exhaustion

@en

P2093

Alina C Boesteanu

http://www.w3.org/2001/XMLSchema#string

Christine M Bucks

http://www.w3.org/2001/XMLSchema#string

Jillian A Norton

http://www.w3.org/2001/XMLSchema#string

Peter D Katsikis

http://www.w3.org/2001/XMLSchema#string

Yvonne M Mueller

http://www.w3.org/2001/XMLSchema#string

P2860

Viral immune evasion due to persistence of activated T cells without effector function

Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome

Sustained Dysfunction of Antiviral CD8+ T Lymphocytes after Infection with Hepatitis C Virus

Liver-Infiltrating Lymphocytes in Chronic Human Hepatitis C Virus Infection Display an Exhausted Phenotype with High Levels of PD-1 and Low Levels of CD127 Expression

Restoring function in exhausted CD8 T cells during chronic viral infection

Control of viremia in simian immunodeficiency virus infection by CD8+ lymphocytes

PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression

Impaired effector function of hepatitis C virus-specific CD8+ T cells in chronic hepatitis C virus infection

Multiple anti-interferon actions of the influenza A virus NS1 protein

A significant number of human immunodeficiency virus epitope-specific cytotoxic T lymphocytes detected by tetramer binding do not produce gamma interferon.

P304

6697-6708

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.4049/JIMMUNOL.0800997

http://www.w3.org/2001/XMLSchema#string

P407

P433

11

http://www.w3.org/2001/XMLSchema#string

P478

182

http://www.w3.org/2001/XMLSchema#string

P577

2009-06-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

24439329

http://www.w3.org/2001/XMLSchema#string

P698

19454664

http://www.w3.org/2001/XMLSchema#string

P932

2923544

http://www.w3.org/2001/XMLSchema#string