Epigenomic analysis of primary human T cells reveals enhancers associated with TH2 memory cell differentiation and asthma susceptibility - Wikidata - awgldk - TriplyDB

Epigenomic analysis of primary human T cells reveals enhancers associated with TH2 memory cell differentiation and asthma susceptibility

Epigenomic analysis of primary human T cells reveals enhancers associated with TH2 memory cell differentiation and asthma susceptibility

http://www.wikidata.org/entity/Q34075540

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Transcriptional Enhancers in the Regulation of T Cell Differentiation Regulation of human helper T cell subset differentiation by cytokines Analyzing and interpreting genome data at the network level with ConsensusPathDB Along the Axis between Type 1 and Type 2 Immunity; Principles Conserved in Evolution from Fish to Mammals Epigenome-modifying tools in asthma Integrative analysis of 111 reference human epigenomes Pathogenic CD4+ T cells in patients with asthma.Genetic and epigenetic variation in the lineage specification of regulatory T cells.QSEA-modelling of genome-wide DNA methylation from sequencing enrichment experiments.Genetic insights into juvenile idiopathic arthritis derived from deep whole genome sequencing.Enhancing the understanding of asthma.Single-cell epigenomics: techniques and emerging applications.Systems biology of asthma and allergic diseases: a multiscale approach Upregulation of Tim-3 on CD4(+) T cells is associated with Th1/Th2 imbalance in patients with allergic asthma.Disease-Associated Single-Nucleotide Polymorphisms From Noncoding Regions in Juvenile Idiopathic Arthritis Are Located Within or Adjacent to Functional Genomic Elements of Human Neutrophils and CD4+ T Cells.Genetic basis of autoimmunity.cChIP-seq: a robust small-scale method for investigation of histone modifications.Identification of a novel cis-regulatory element essential for immune tolerance.The cAMP response element modulator (CREM) regulates TH2 mediated inflammation Innate-like functions of natural killer T cell subsets result from highly divergent gene programs Pax6 associates with H3K4-specific histone methyltransferases Mll1, Mll2, and Set1a and regulates H3K4 methylation at promoters and enhancers.17q21 asthma-risk variants switch CTCF binding and regulate IL-2 production by T cells.Chromatin landscapes and genetic risk in systemic lupus.Rapid Recall Ability of Memory T cells is Encoded in their Epigenome.TH9 cell differentiation, transcriptional control and function in inflammation, autoimmune diseases and cancer.Epigenomics of autoimmune diseases.Asthma Pharmacogenomics: 2015 Update.Histone Modifications and Asthma. The Interface of the Epigenetic and Genetic Landscapes.Using omics approaches to understand pulmonary diseases.Interaction between allergic asthma and atherosclerosis.The environment, epigenome, and asthma.Inducible chromatin priming is associated with the establishment of immunological memory in T cells.CD4+ T-cell subsets in inflammatory diseases: beyond the Th1/Th2 paradigm.ChIP-seq in studying epigenetic mechanisms of disease and promoting precision medicine: progresses and future directions.Regulation of IL-4 Expression in Immunity and Diseases.Immune disease-associated variants in gene enhancers point to BET epigenetic mechanisms for therapeutic intervention.Chronic allergic pulmonary inflammation is aggravated in angiotensin-(1-7) Mas receptor knockout mice.Development of allergic immunity in early life.Epigenetic regulation of T-helper cell differentiation, memory, and plasticity in allergic asthma.Priming of transcriptional memory responses via the chromatin accessibility landscape in T cells.

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Epigenomic analysis of primary human T cells reveals enhancers associated with TH2 memory cell differentiation and asthma susceptibility

http://www.wikidata.org/entity/Q34075540

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2014 nî lūn-bûn

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Anjana Rao

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Anna Gerasimova

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Asha Purnima V Ganesan

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Ashu Chawla

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Grégory Seumois

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Lukas Kalinke

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Maria Vedanayagam

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Matthias Lienhard

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Nada Omran

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Pandurangan Vijayanand

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P2860

Predicting cell types and genetic variations contributing to disease by combining GWAS and epigenetic data

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

Differential expression analysis for sequence count data

Identification of a Coordinate Regulator of Interleukins 4, 13, and 5 by Cross-Species Sequence Comparisons

An integrated map of genetic variation from 1,092 human genomes

Widespread plasticity in CTCF occupancy linked to DNA methylation

Histone H3K27ac separates active from poised enhancers and predicts developmental state

Analysis of the vertebrate insulator protein CTCF-binding sites in the human genome

TopHat: discovering splice junctions with RNA-Seq

Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4+ T cells

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10.1038/NI.2937

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8

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15

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Ratko Djukanovic

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2014-07-06T00:00:00Z

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263710256

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4140783

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