Altered glycan-dependent signaling induces insulin resistance and hyperleptinemia
about
Elevated O-GlcNAc-dependent signaling through inducible mOGT expression selectively triggers apoptosisHexosamines, insulin resistance, and the complications of diabetes: current status.Caenorhabditis elegans ortholog of a diabetes susceptibility locus: oga-1 (O-GlcNAcase) knockout impacts O-GlcNAc cycling, metabolism, and dauerInsulin receptor signaling in normal and insulin-resistant statesFunctional O-GlcNAc modifications: implications in molecular regulation and pathophysiologyO-GlcNAcylation and Metabolic Reprograming in CancerElevation of Global O-GlcNAc Levels in 3T3-L1 Adipocytes by Selective Inhibition of O-GlcNAcase Does Not Induce Insulin ResistanceGlcNAcstatins are nanomolar inhibitors of human O -GlcNAcase inducing cellular hyper- O -GlcNAcylationSubstrate and product analogues as human O-GlcNAc transferase inhibitorsInhibition of a bacterial O-GlcNAcase homologue by lactone and lactam derivatives: structural, kinetic and thermodynamic analysesInhibition of O-GlcNAcase Using a Potent and Cell-Permeable Inhibitor Does Not Induce Insulin Resistance in 3T3-L1 AdipocytesGaining insight into the inhibition of glycoside hydrolase family 20 exo-β-N-acetylhexosaminidases using a structural approachThe hexosamine signaling pathway: deciphering the "O-GlcNAc code"A PGC-1alpha-O-GlcNAc transferase complex regulates FoxO transcription factor activity in response to glucose.O-GlcNAc regulates FoxO activation in response to glucose.O-GlcNAc cycling mutants modulate proteotoxicity in Caenorhabditis elegans models of human neurodegenerative diseases.O-GlcNAc modifications regulate cell survival and epiboly during zebrafish development.The hexosamine signaling pathway: O-GlcNAc cycling in feast or famineThe essential role of YAP O-GlcNAcylation in high-glucose-stimulated liver tumorigenesisQuantitative secretome and glycome of primary human adipocytes during insulin resistance.Dynamic O-GlcNAc cycling at promoters of Caenorhabditis elegans genes regulating longevity, stress, and immunity.A Caenorhabditis elegans model of insulin resistance: altered macronutrient storage and dauer formation in an OGT-1 knockout.Increased expression of beta-N-acetylglucosaminidase in erythrocytes from individuals with pre-diabetes and diabetes.O-GlcNAc signaling in the cardiovascular system.O-GlcNAc signaling: a metabolic link between diabetes and cancer?Blocking O-linked GlcNAc cycling in Drosophila insulin-producing cells perturbs glucose-insulin homeostasis.OGA inhibition by GlcNAc-selenazolineVersatile O-GlcNAc transferase assay for high-throughput identification of enzyme variants, substrates, and inhibitors.Hepatic FoxO1 integrates glucose utilization and lipid synthesis through regulation of Chrebp O-glycosylation.O-GlcNAcylation: a novel post-translational mechanism to alter vascular cellular signaling in health and disease: focus on hypertension.Increased hexosamine pathway flux and high fat feeding are not additive in inducing insulin resistance: evidence for a shared pathwayDisruption of O-GlcNAc Cycling in C. elegans Perturbs Nucleotide Sugar Pools and Complex Glycans.O-GlcNAcylation: a novel pathway contributing to the effects of endothelin in the vasculature.O-GlcNAc and the epigenetic regulation of gene expression.Multiple tissue-specific roles for the O-GlcNAc post-translational modification in the induction of and complications arising from type II diabetes.Global O-GlcNAc Levels Modulate Transcription of the Adipocyte Secretome during Chronic Insulin Resistance.O-linked-N-acetylglucosamine cycling and insulin signaling are required for the glucose stress response in Caenorhabditis elegansIdentification of O-GlcNAc modification targets in mouse retinal pericytes: implication of p53 in pathogenesis of diabetic retinopathy.O-GlcNAc turns twenty: functional implications for post-translational modification of nuclear and cytosolic proteins with a sugar.Conditional knock-out reveals a requirement for O-linked N-Acetylglucosaminase (O-GlcNAcase) in metabolic homeostasis
P2860
Q24299073-8ED8802A-6365-472F-BED0-86456408FB13Q24538581-A88AF5E6-CF70-4E52-9C85-7442DF7BB910Q24670972-A7CAABDA-4FD2-4B59-B5F3-C23C57312364Q26823171-71127EE9-729D-4C58-A6E0-19E27A762854Q27009399-40FF6E80-5A16-474D-94FE-261F7FAE3B5EQ27027028-BA0DBCF5-A026-4146-BE68-78A68EAF1EA0Q27652457-8449028E-491C-44DC-AA8B-0C3483AC99BEQ27654050-F02C73E6-EDAF-48EF-A187-A36D3C8F62AFQ27663568-B784D2C5-F161-4324-B6D4-74630689592BQ27663888-A026BBBA-C2F7-4AE5-BD06-F63861A437A7Q27664569-58CC0C80-1FF1-4F96-ACCE-F25F4E00E489Q27677503-4214D6D8-47DB-4D53-B01B-205DAD8A5EC8Q28284365-FC993938-D71D-483D-A34A-2587B0F2B2CCQ30437005-2F1040C0-3684-435E-A645-04149105FFFBQ30439420-D8FD78A8-07A3-4C2B-9874-AA4D9CE4CD32Q30528027-29F5C77B-B2D8-4226-BC8D-9BD86262C369Q33433251-1FF8589B-8616-4302-B45F-E84A6BAFB16EQ33625053-59ED0C1A-F322-437A-9095-D49F24ACDBACQ33654365-54E981C4-41ED-4B5A-A07E-C9C7DC868300Q33749585-DE8D2477-393F-4306-94C1-3DCB5F2D61E2Q33842100-8BB05B56-1194-4CEC-A03B-2C1938AC75CFQ33913856-716A3A00-6866-4E28-A90C-994500D2C960Q33930349-91068AEB-B210-4D99-A949-D2E053FA9E4BQ34056858-8C21CE3F-63E0-43E7-8F7D-D7FE5CC776EDQ34172895-78135297-C0D1-45F7-A82C-A0D0077540DFQ34352417-249CF029-CCFE-4766-BBCB-EE6C3511B44CQ34411395-7A214D6B-71C8-43A6-BA7E-A199C02686CCQ34434068-425706DC-E0DF-418F-9D02-40C80C43D7FFQ34442922-2F3C30F5-D5EB-4A09-B727-55E4EBB33C22Q34498193-788C6923-B0C7-477D-94DF-8A1D50F6EA2EQ34538415-EAB28F79-D3C7-4BDB-8D5F-1E6C84DCDBACQ34562985-666E6FBA-0C56-4E01-A936-0D235647DB87Q34598611-992152BF-847A-4920-962F-D8AA4707ED41Q34683048-35B6631E-71E6-48B2-AADB-B66545B23D18Q34683091-C426CCC3-D0D3-433F-AE84-4188B7E0FE27Q34999404-1B8F7863-EAF4-47D7-AFAE-B4AB70BC3B77Q35065486-26419454-278B-4AC2-A6E3-99D0ECC53D61Q35161621-CCDA1EC1-4AD6-4257-8F79-2CEF7AD51D5CQ35163991-42C4037C-C90D-4F41-AA2D-D2668290AF03Q35172669-7DF40B8F-6CA4-4F90-A65A-9B7418D9C42D
P2860
Altered glycan-dependent signaling induces insulin resistance and hyperleptinemia
description
2002 nî lūn-bûn
@nan
2002 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Altered glycan-dependent signaling induces insulin resistance and hyperleptinemia
@ast
Altered glycan-dependent signaling induces insulin resistance and hyperleptinemia
@en
Altered glycan-dependent signaling induces insulin resistance and hyperleptinemia
@nl
type
label
Altered glycan-dependent signaling induces insulin resistance and hyperleptinemia
@ast
Altered glycan-dependent signaling induces insulin resistance and hyperleptinemia
@en
Altered glycan-dependent signaling induces insulin resistance and hyperleptinemia
@nl
prefLabel
Altered glycan-dependent signaling induces insulin resistance and hyperleptinemia
@ast
Altered glycan-dependent signaling induces insulin resistance and hyperleptinemia
@en
Altered glycan-dependent signaling induces insulin resistance and hyperleptinemia
@nl
P2093
P2860
P356
P1476
Altered glycan-dependent signaling induces insulin resistance and hyperleptinemia
@en
P2093
Dona C Love
Glendon J Parker
John A Hanover
Mark Hazel
Robert C Cooksey
William A Lubas
P2860
P304
10695-10699
P356
10.1073/PNAS.152346899
P407
P577
2002-07-22T00:00:00Z