Leptin promotes the proliferative response and invasiveness in human endometrial cancer cells by activating multiple signal-transduction pathways. - Wikidata - awgldk - TriplyDB

Leptin promotes the proliferative response and invasiveness in human endometrial cancer cells by activating multiple signal-transduction pathways.

Leptin promotes the proliferative response and invasiveness in human endometrial cancer cells by activating multiple signal-transduction pathways.

http://www.wikidata.org/entity/Q34078555

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Role of leptin and its receptors in the pathogenesis of thyroid cancer Obesity in cancer survival Leptin and its cardiovascular effects: Focus on angiogenesis Obesity and cancer: the role of adipose tissue and adipo-cytokines-induced chronic inflammation Glioblastoma-derived leptin induces tube formation and growth of endothelial cells: comparison with VEGF effects Adiponectin antagonizes the oncogenic actions of leptin in hepatocellular carcinogenesis.Leptin and Adiponectin: new players in the field of tumor cell and leukocyte migration.Leptin regulation of proangiogenic molecules in benign and cancerous endometrial cells.Concomitant activation of the JAK/STAT, PI3K/AKT, and ERK signaling is involved in leptin-mediated promotion of invasion and migration of hepatocellular carcinoma cells Metabolic health reduces risk of obesity-related cancer in framingham study adults.Leptin promotes the myofibroblastic phenotype in hepatic stellate cells by activating the hedgehog pathway.Reduction in neural activation to high-calorie food cues in obese endometrial cancer survivors after a behavioral lifestyle intervention: a pilot study.Biology of obesity: lessons from animal models of obesity Obesity, adipocytokines and cancer Benzyl isothiocyanate inhibits oncogenic actions of leptin in human breast cancer cells by suppressing activation of signal transducer and activator of transcription 3.An exploratory investigation of links between changes in adipokines and quality of life in individuals undergoing weight loss interventions: possible implications for cancer research.Bidirectional crosstalk between leptin and insulin-like growth factor-I signaling promotes invasion and migration of breast cancer cells via transactivation of epidermal growth factor receptor Reduced mitogenicity of sera following weight loss in premenopausal women.Dose-dependent biphasic leptin-induced proliferation is caused by non-specific IL-6/NF-κB pathway activation in human myometrial cells Survivin upregulation, dependent on leptin-EGFR-Notch1 axis, is essential for leptin-induced migration of breast carcinoma cells.Paracrine and endocrine effects of adipose tissue on cancer development and progression.Leptin activation of mTOR pathway in intestinal epithelial cell triggers lipid droplet formation, cytokine production and increased cell proliferation.Diabetic angiopathy and angiogenic defects.Multifaceted leptin network: the molecular connection between obesity and breast cancer.Integral role of PTP1B in adiponectin-mediated inhibition of oncogenic actions of leptin in breast carcinogenesis.Leptin's mitogenic effect in human liver cancer cells requires induction of both methionine adenosyltransferase 2A and 2beta Targeting obesity-related adipose tissue dysfunction to prevent cancer development and progression.Differential effects of leptin on the invasive potential of androgen-dependent and -independent prostate carcinoma cells.Obesity, energy balance, and cancer: new opportunities for prevention Mechanisms linking obesity and cancer Leptin serves as angiogenic/mitogenic factor in melanoma tumor growth.Serum leptin, adiponectin and endometrial cancer risk in Chinese women.Leptin receptor maintains cancer stem-like properties in triple negative breast cancer cells.Obesity, insulin resistance, and cancer prognosis: implications for practice for providing care among cancer survivors.Leptin expression in proliferative, secretory and hyperplastic endometrial tissues.Obesity is associated with higher 4E-BP1 expression in endometrial cancer.Role of dysregulated expression of leptin and leptin receptors in colorectal carcinogenesis.Role of leptin and leptin receptors in hematological malignancies.Leptin induced GRP78 expression through the PI3K-mTOR pathway in neuronal cells.Recombinant human leptin induces growth inhibition and apoptosis in human gastric cancer MGC-803 cells.

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P2860

Leptin promotes the proliferative response and invasiveness in human endometrial cancer cells by activating multiple signal-transduction pathways.

http://www.wikidata.org/entity/Q34078555

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2006 nî lūn-bûn

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2006年の論文

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Leptin promotes the proliferat ...... signal-transduction pathways.

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Leptin promotes the proliferat ...... signal-transduction pathways.

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P2860

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

Evidence of free and bound leptin in human circulation. Studies in lean and obese subjects and during short-term fasting

Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults

Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

Regulation of cell death protease caspase-9 by phosphorylation

The leptin receptor

The role of SOCS-3 in leptin signaling and leptin resistance

Divergent signaling capacities of the long and short isoforms of the leptin receptor

STATs in oncogenesis

Weight-reducing effects of the plasma protein encoded by the obese gene

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