about
Nilotinib and MEK inhibitors induce synthetic lethality through paradoxical activation of RAF in drug-resistant chronic myeloid leukemiaCCN3 suppresses mitogenic signalling and reinstates growth control mechanisms in Chronic Myeloid LeukaemiaGATA-1 and Gfi-1B interplay to regulate Bcl-xL transcriptionUbp43 regulates BCR-ABL leukemogenesis via the type 1 interferon receptor signalingA stochastic model of oncogene expression and the relevance of this model to cancer therapy.BMI1: A Biomarker of Hematologic MalignanciesMicroRNAs mediated regulation of MAPK signaling pathways in chronic myeloid leukemiaHsp90 Inhibitors for the Treatment of Chronic Myeloid LeukemiaHedgehog Signaling in the Maintenance of Cancer Stem CellsBiomarkers for determining the prognosis in chronic myelogenous leukemiaMechanisms of epigenetic regulation of leukemia onset and progressionThe growing arsenal of ATP-competitive and allosteric inhibitors of BCR-ABLThe role of the JAK-STAT pathway and related signal cascades in telomerase activation during the development of hematologic malignanciesJNK signalling in cancer: in need of new, smarter therapeutic targetsSignal transduction in the chronic leukemias: implications for targeted therapiesDissection of the BCR-ABL signaling network using highly specific monobody inhibitors to the SHP2 SH2 domainsDiscovery and characterization of a novel potent type II native and mutant BCR-ABL inhibitor (CHMFL-074) for Chronic Myeloid Leukemia (CML)Ponatinib is a pan-BCR-ABL kinase inhibitor: MD simulations and SIE studyAclacinomycin A sensitizes K562 chronic myeloid leukemia cells to imatinib through p38MAPK-mediated erythroid differentiationGefitinib-induced killing of NSCLC cell lines expressing mutant EGFR requires BIM and can be enhanced by BH3 mimeticsAcadesine kills chronic myelogenous leukemia (CML) cells through PKC-dependent induction of autophagic cell deathChronic myeloid leukemia patients in prolonged remission following interferon-α monotherapy have distinct cytokine and oligoclonal lymphocyte profileDynamics of resistance development to imatinib under increasing selection pressure: a combination of mathematical models and in vitro dataA natural-like synthetic small molecule impairs bcr-abl signaling cascades and induces megakaryocyte differentiation in erythroleukemia cellsDisabled-2 is transcriptionally regulated by ICSBP and augments macrophage spreading and adhesion.A mutation in the Icsbp1 gene causes susceptibility to infection and a chronic myeloid leukemia-like syndrome in BXH-2 miceBCR-ABL affects STAT5A and STAT5B differentiallyEvolution of the cancer genomeIcaritin shows potent anti-leukemia activity on chronic myeloid leukemia in vitro and in vivo by regulating MAPK/ERK/JNK and JAK2/STAT3 /AKT signalingsABL fusion oncogene transformation and inhibitor sensitivity are mediated by the cellular regulator RIN1.Activation state-selective kinase inhibitor assay based on ion mobility-mass spectrometryPYRROLO[1,2-b][1,2,5]BENZOTHIADIAZEPINES (PBTDs) induce apoptosis in K562 cells.Downregulation of miR-31, miR-155, and miR-564 in chronic myeloid leukemia cellsEfficacy and safety of radotinib in chronic phase chronic myeloid leukemia patients with resistance or intolerance to BCR-ABL1 tyrosine kinase inhibitors.Abl kinase inhibits the engulfment of apoptotic [corrected] cells in Caenorhabditis elegansThe derivation of diagnostic markers of chronic myeloid leukemia progression from microarray data.Quantitative assay for the detection of the V617F variant in the Janus kinase 2 (JAK2) gene using the Luminex xMAP technology.Biology-driven cancer drug development: back to the futurePI3K isoform inhibition associated with anti Bcr-Abl drugs shows in vitro increased anti-leukemic activity in Philadelphia chromosome-positive B-acute lymphoblastic leukemia cell linesSmac mimetics: implications for enhancement of targeted therapies in leukemia
P2860
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P2860
description
2000 nî lūn-bûn
@nan
2000 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
The molecular biology of chronic myeloid leukemia.
@ast
The molecular biology of chronic myeloid leukemia.
@en
The molecular biology of chronic myeloid leukemia.
@nl
type
label
The molecular biology of chronic myeloid leukemia.
@ast
The molecular biology of chronic myeloid leukemia.
@en
The molecular biology of chronic myeloid leukemia.
@nl
prefLabel
The molecular biology of chronic myeloid leukemia.
@ast
The molecular biology of chronic myeloid leukemia.
@en
The molecular biology of chronic myeloid leukemia.
@nl
P2093
P1433
P1476
The molecular biology of chronic myeloid leukemia
@en
P2093
P304
P407
P577
2000-11-01T00:00:00Z