Complexes of two cohorts of CLIP peptides and HLA-DQ2 of the autoimmune DR3-DQ2 haplotype are poor substrates for HLA-DM - Wikidata - awgldk - TriplyDB

Complexes of two cohorts of CLIP peptides and HLA-DQ2 of the autoimmune DR3-DQ2 haplotype are poor substrates for HLA-DM

Complexes of two cohorts of CLIP peptides and HLA-DQ2 of the autoimmune DR3-DQ2 haplotype are poor substrates for HLA-DM

http://www.wikidata.org/entity/Q34083338

about

Human leukocyte Antigen-DM polymorphisms in autoimmune diseases Bidirectional binding of invariant chain peptides to an MHC class II molecule Susceptibility to HLA-DM Protein Is Determined by a Dynamic Conformation of Major Histocompatibility Complex Class II Molecule Bound with Peptide Assembly and architecture of the EBV B cell entry triggering complex Differences in the risk of celiac disease associated with HLA-DQ2.5 or HLA-DQ2.2 are related to sustained gluten antigen presentation.MultiRTA: a simple yet reliable method for predicting peptide binding affinities for multiple class II MHC allotypes.I-Ag7 is subject to post-translational chaperoning by CLIP.Cutting edge: HLA-DM functions through a mechanism that does not require specific conserved hydrogen bonds in class II MHC-peptide complexes.On the perils of poor editing: regulation of peptide loading by HLA-DQ and H2-A molecules associated with celiac disease and type 1 diabetes.Pulse-chase analysis for studies of MHC class II biosynthesis, maturation, and peptide loading.The nonconventional MHC class II molecule DM governs diabetes susceptibility in NOD mice The melting pot of the MHC II peptidome Different binding motifs of the celiac disease-associated HLA molecules DQ2.5, DQ2.2, and DQ7.5 revealed by relative quantitative proteomics of endogenous peptide repertoires Cell-surface MHC density profiling reveals instability of autoimmunity-associated HLA.Resolving multiple protein-peptide binding events: implication for HLA-DQ2 mediated antigen presentation in celiac disease.CD62L(neg)CD38⁺ expression on circulating CD4⁺ T cells identifies mucosally differentiated cells in protein fed mice and in human celiac disease patients and controls Mechanisms of peptide repertoire selection by HLA-DM Exposing the Specific Roles of the Invariant Chain Isoforms in Shaping the MHC Class II Peptidome.Antigen presentation in celiac disease.The Repertoires of Peptides Presented by MHC-II in the Thymus and in Peripheral Tissue: A Clue for Autoimmunity?Structural Insights Into HLA-DM Mediated MHC II Peptide Exchange.Type 1 diabetes associated HLA-DQ2 and DQ8 molecules are relatively resistant to HLA-DM mediated release of invariant chain-derived CLIP peptides Peptidomic analysis of type 1 diabetes associated HLA-DQ molecules and the impact of HLA-DM on peptide repertoire editing.Direct cloning and tetramer staining to measure the frequency of intestinal gluten-reactive T cells in celiac disease.HLA-DQ2-restricted gluten-reactive T cells produce IL-21 but not IL-17 or IL-22.DM influences the abundance of major histocompatibility complex class II alleles with low affinity for class II-associated invariant chain peptides via multiple mechanisms.A TCRα framework-centered codon shapes a biased T cell repertoire through direct MHC and CDR3β interactions.MHC class II complexes sample intermediate states along the peptide exchange pathway.An insertion mutant in DQA1*0501 restores susceptibility to HLA-DM: implications for disease associations.Unraveling the structural basis for the unusually rich association of human leukocyte antigen DQ2.5 with class-II-associated invariant chain peptides.Soluble T-cell receptor design influences functional yield in an E. coli chaperone-assisted expression system.Quantification of HLA-DM-Dependent Major Histocompatibility Complex of Class II Immunopeptidomes by the Peptide Landscape Antigenic Epitope Alignment Utility.

P2860

Q26741035-B1B204D9-3F0D-40E5-970D-53C34F30806E Q27666102-95B66716-3401-4C87-8EEB-DBDD97D88AB7 Q27684590-DCB2A47E-6ED4-40CE-8FA2-2C411A60AC54 Q28542501-58F6B104-AF3C-4609-BD3A-CB9962AFC6BA Q33498360-9D901291-1451-4170-8400-3FF8C1B0A2E1 Q33702755-EE0904A5-4EC2-4195-8847-C08AC29486CE Q34013568-72152E9B-FDA5-4B6B-A98B-B95D66A2B11F Q34028384-EDCF887F-A768-4ACB-A81D-704CCA014E88 Q34150236-65800CA2-AE88-446A-AA25-4BAD2B46B406 Q34155809-60FE46E6-2ABE-47E2-A423-D67E205117E7 Q34590244-B55A1C34-F7AE-4410-B2F8-618763B89481 Q34676583-605236A4-F0D1-4D60-A4EE-CE410251F195 Q34978613-772B8B00-8465-49B0-9728-DB59639EDADC Q35242376-40E69582-C676-41BA-A7FA-10F589C7EECE Q36055610-44AD22C6-CD4A-408E-8B01-9D0ACC7484EB Q36966610-C23D57D5-D05D-47DD-A1D7-D3A9425F87BB Q37228066-6923F17E-5BD3-4FCE-BE78-1391CA878630 Q37389304-8E064BB5-4766-40E0-A631-1D5E176F013F Q37430981-D40CE011-965E-45F6-8C50-9D87ABA98A39 Q38175024-1B0F71C5-0B90-41D1-9911-22CB4AF53485 Q38255165-03C523F7-F293-41BF-A970-5D82E3367FCC Q38808868-A55F3332-37CB-4456-9B65-183C9F2F010F Q39175672-E3F31890-95B0-4488-8A65-EEE1B0EE80CE Q39400903-125EE662-929C-4CCB-A89D-61C2A6C019F6 Q39689282-244B3DA9-4018-4233-A3A9-FBDF024D2976 Q39712353-44697FFA-E1B5-4BC1-955D-0CC1C956BF47 Q40063793-694222F1-A260-4A79-9DF8-4A24B1882BE6 Q40482918-362BDFA8-C617-4F40-9C44-0404CC82260A Q42873027-83B25DEA-D5CF-407F-B6C0-AC862A5F272D Q51079315-00F27694-7663-42AC-A0FB-8C88F974E96D Q54205671-0CA9A1F6-1419-4148-916C-B12F56ABFE6C Q55067919-35AD6B15-9ECE-495D-9325-D8C599A7B37F

P2860

Complexes of two cohorts of CLIP peptides and HLA-DQ2 of the autoimmune DR3-DQ2 haplotype are poor substrates for HLA-DM

http://www.wikidata.org/entity/Q34083338

description

2008 nî lūn-bûn

@nan

2008 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

2008年の論文

@ja

2008年論文

@yue

2008年論文

@zh-hant

2008年論文

@zh-hk

2008年論文

@zh-mo

2008年論文

@zh-tw

2008年论文

@wuu

name

Complexes of two cohorts of CL ...... are poor substrates for HLA-DM

@ast

Complexes of two cohorts of CL ...... are poor substrates for HLA-DM

@en

Complexes of two cohorts of CL ...... are poor substrates for HLA-DM

@nl

type

label

Complexes of two cohorts of CL ...... are poor substrates for HLA-DM

@ast

Complexes of two cohorts of CL ...... are poor substrates for HLA-DM

@en

Complexes of two cohorts of CL ...... are poor substrates for HLA-DM

@nl

prefLabel

Complexes of two cohorts of CL ...... are poor substrates for HLA-DM

@ast

Complexes of two cohorts of CL ...... are poor substrates for HLA-DM

@en

Complexes of two cohorts of CL ...... are poor substrates for HLA-DM

@nl

P1433

Q34083338-186EC316-987B-4178-87EC-52A11F44DE88

P1476

Q34083338-6205988E-B72F-4DE5-9085-E42994265C21

P2093

Q34083338-25D3FEDE-E576-493A-ADBE-B735143A3596

Q34083338-31CDB5ED-0A99-4040-8980-4BD2C14D6928

Q34083338-3C8B4349-D7F8-4522-B1EC-A08B74566735

Q34083338-52C36F6B-C594-49C5-96E4-989825E0742B

Q34083338-59287510-7A76-41BC-A2BC-8983FF59D004

Q34083338-5B6481CC-A4DD-425C-80B3-7DE5548862F3

Q34083338-60F0130F-76E0-4BAD-BAA4-94FE75D6B85D

Q34083338-622F8D3D-5627-445C-B86D-B919F60386F7

Q34083338-E09F61FC-DAFE-4778-9BAA-60234BCC6443

P2860

Q34083338-0B669382-8B39-42B7-B5C2-0AF150DD1BD4

Q34083338-0D32A0C6-A663-4841-BBE3-C1FBACC59E8E

Q34083338-1FF282AA-71CE-4512-AF06-D3525515793B

Q34083338-2CDBBC5A-349C-4F9B-BC72-067F992659E6

Q34083338-502BA6B4-DB2B-470F-9B16-801C505E5A43

Q34083338-5D91D5C1-DA82-4963-9FAC-1A7A6C437634

Q34083338-69C79B40-87F2-41BB-ABBD-6080B4E2B991

Q34083338-6B07DD1A-056F-4CFD-AB9D-C3B8BE6805DA

Q34083338-6E6477FE-D8C5-49D5-A64D-6C26AB2AFF23

Q34083338-6F10DF46-E19E-4280-8C8C-264A1834E032

P304

Q34083338-45D3594B-9153-48A9-B396-FD1A9CA10C40

P31

Q34083338-227C467F-7B30-43E9-A986-0C547D25721F

P356

Q34083338-7458929F-5A79-46C4-A046-D59AE1325CDB

P407

Q34083338-F55C7733-AEE1-4350-8A38-8AE6094700C8

P433

Q34083338-AAF77543-B771-46F3-943B-4ADDB0120123

P478

Q34083338-6CD80833-C59F-4EF2-923A-A13DACDF9BB4

P577

Q34083338-25F4C950-E8C1-4DB0-A13A-F47F11193D81

P698

Q34083338-F815AC7F-2FFC-4D0E-9604-71BD2144D5C6

P932

Q34083338-F36AE5A9-46B3-4436-BF9A-D2FBCCA4B2AF

P356

JIMMUNOL.181.8.5451

P1433

Journal of Immunology

P1476

Complexes of two cohorts of CL ...... are poor substrates for HLA-DM

@en

P2093

Anders Holm

http://www.w3.org/2001/XMLSchema#string

Arunima Bandyopadhyay

http://www.w3.org/2001/XMLSchema#string

Burkhard Fleckenstein

http://www.w3.org/2001/XMLSchema#string

Elin Bergseng

http://www.w3.org/2001/XMLSchema#string

Elizabeth D Mellins

http://www.w3.org/2001/XMLSchema#string

Lars-Egil Fallang

http://www.w3.org/2001/XMLSchema#string

Ludvig M Sollid

http://www.w3.org/2001/XMLSchema#string

Sujin Roh

http://www.w3.org/2001/XMLSchema#string

Taejin Yoon

http://www.w3.org/2001/XMLSchema#string

P2860

The structure of an intermediate in class II MHC maturation: CLIP bound to HLA-DR3

Structural basis for HLA-DQ2-mediated presentation of gluten epitopes in celiac disease

The HLA-DQ2 gene dose effect in celiac disease is directly related to the magnitude and breadth of gluten-specific T cell responses

The structure of HLA-DM, the peptide exchange catalyst that loads antigen onto class II MHC molecules during antigen presentation

Interaction of HLA-DR with an acidic face of HLA-DM disrupts sequence-dependent interactions with peptides

Achieving stability through editing and chaperoning: regulation of MHC class II peptide binding and expression

The peptide binding motif of the disease associated HLA-DQ (alpha 1* 0501, beta 1* 0201) molecule

Enhanced dissociation of HLA-DR-bound peptides in the presence of HLA-DM

Determination of the HLA-DM interaction site on HLA-DR molecules.

The genetic basis for the association of the 8.1 ancestral haplotype (A1, B8, DR3) with multiple immunopathological diseases.

P304

5451-5461

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.4049/JIMMUNOL.181.8.5451

http://www.w3.org/2001/XMLSchema#string

P407

P433

8

http://www.w3.org/2001/XMLSchema#string

P478

181

http://www.w3.org/2001/XMLSchema#string

P577

2008-10-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

18832702

http://www.w3.org/2001/XMLSchema#string

P932

4143156

http://www.w3.org/2001/XMLSchema#string