Antigen potency and maximal efficacy reveal a mechanism of efficient T cell activation. - Wikidata - awgldk - TriplyDB

Antigen potency and maximal efficacy reveal a mechanism of efficient T cell activation.

Antigen potency and maximal efficacy reveal a mechanism of efficient T cell activation.

http://www.wikidata.org/entity/Q34086610

about

An induced rebinding model of antigen discrimination WIPI-Mediated Autophagy and Longevity Experimental and theoretical bases for mechanisms of antigen discrimination by T cells Systems model of T cell receptor proximal signaling reveals emergent ultrasensitivity.Mechanical modulation of receptor-ligand interactions at cell-cell interfaces.Interplay between T cell receptor binding kinetics and the level of cognate peptide presented by major histocompatibility complexes governs CD8+ T cell responsiveness.Multisite Phosphorylation Modulates the T Cell Receptor ζ-Chain Potency but not the Switchlike Response.Cellular-level versus receptor-level response threshold hierarchies in T-cell activation.Structure-Based, Rational Design of T Cell Receptors.Can non-lytic CD8+ T cells drive HIV-1 escape?Architecture of a minimal signaling pathway explains the T-cell response to a 1 million-fold variation in antigen affinity and dose.2D TCR-pMHC-CD8 kinetics determines T-cell responses in a self-antigen-specific TCR system.Heterogeneity assessment of functional T cell avidity.Non-catalytic tyrosine-phosphorylated receptors.Mathematical Models for Immunology: Current State of the Art and Future Research Directions.T lymphocytes need less than 3 min to discriminate between peptide MHCs with similar TCR-binding parameters.Improved ligand discrimination by force-induced unbinding of the T cell receptor from peptide-MHC.Meeting report: Signal transduction meets systems biology.Coreceptor scanning by the T cell receptor provides a mechanism for T cell tolerance.TCR/pMHC Interaction: Phenotypic Model for an Unsolved Enigma.A stochastic T cell response criterion.The Serial Engagement Model 17 Years After: From TCR Triggering to Immunotherapy.PD-L1 blockade enhances response of pancreatic ductal adenocarcinoma to radiotherapy.Comparison of T Cell Activities Mediated by Human TCRs and CARs That Use the Same Recognition Domains.

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P2860

Antigen potency and maximal efficacy reveal a mechanism of efficient T cell activation.

http://www.wikidata.org/entity/Q34086610

description

2011 nî lūn-bûn

@nan

2011 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2011 թվականի հունիսին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

@zh-hant

2011年論文

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2011年論文

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2011年論文

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2011年论文

@wuu

name

Antigen potency and maximal efficacy reveal a mechanism of efficient T cell activation.

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Antigen potency and maximal efficacy reveal a mechanism of efficient T cell activation.

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Antigen potency and maximal efficacy reveal a mechanism of efficient T cell activation.

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type

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Antigen potency and maximal efficacy reveal a mechanism of efficient T cell activation.

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Antigen potency and maximal efficacy reveal a mechanism of efficient T cell activation.

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Antigen potency and maximal efficacy reveal a mechanism of efficient T cell activation.

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prefLabel

Antigen potency and maximal efficacy reveal a mechanism of efficient T cell activation.

@ast

Antigen potency and maximal efficacy reveal a mechanism of efficient T cell activation.

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Antigen potency and maximal efficacy reveal a mechanism of efficient T cell activation.

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SCISIGNAL.2001430

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Science Signaling

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Antigen potency and maximal efficacy reveal a mechanism of efficient T cell activation.

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P2093

Hao Zhang

http://www.w3.org/2001/XMLSchema#string

Ji-Li Chen

http://www.w3.org/2001/XMLSchema#string

Milos Aleksic

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Tao Dong

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Yan-Chun Peng

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P2860

T cell activation

Binding, gating, affinity and efficacy: the interpretation of structure-activity relationships for agonists and of the effects of mutating receptors

Modeling T cell antigen discrimination based on feedback control of digital ERK responses

Evidence that structural rearrangements and/or flexibility during TCR binding can contribute to T cell activation

Single cell analysis reveals regulated hierarchical T cell antigen receptor signaling thresholds and intraclonal heterogeneity for individual cytokine responses of CD4+ T cells

Models for the specific adhesion of cells to cells

A role for rebinding in rapid and reliable T cell responses to antigen

Relating TCR-peptide-MHC affinity to immunogenicity for the design of tumor vaccines

High-affinity TCRs generated by phage display provide CD4+ T cells with the ability to recognize and kill tumor cell lines.

The Goldilocks model for TCR-too much attraction might not be best for vaccine design

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ra39

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scholarly article

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10.1126/SCISIGNAL.2001430

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176

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4

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Vincenzo Cerundolo

Richard John Wheeler

Philip Anton van der Merwe

Shaun-Paul Cordoba

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2011-06-07T00:00:00Z

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21653229

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