Resveratrol inhibits renal fibrosis in the obstructed kidney: potential role in deacetylation of Smad3 - Wikidata - awgldk - TriplyDB

Resveratrol inhibits renal fibrosis in the obstructed kidney: potential role in deacetylation of Smad3

Resveratrol inhibits renal fibrosis in the obstructed kidney: potential role in deacetylation of Smad3

http://www.wikidata.org/entity/Q34086829

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SIRT1 and Kidney Function SIRT1: A Novel Target for the Treatment of Muscular Dystrophies Mitochondria: a new therapeutic target in chronic kidney disease Effect of redox modulating NRF2 activators on chronic kidney disease Role of nutrient-sensing signals in the pathogenesis of diabetic nephropathy Piceatannol Attenuates Renal Fibrosis Induced by Unilateral Ureteral Obstruction via Downregulation of Histone Deacetylase 4/5 or p38-MAPK Signaling Role of transcription factor acetylation in diabetic kidney disease.Blocking sirtuin 1 and 2 inhibits renal interstitial fibroblast activation and attenuates renal interstitial fibrosis in obstructive nephropathy.Inhibition of STAT3 acetylation is associated with angiotesin renal fibrosis in the obstructed kidney.SIRT1 is required for AMPK activation and the beneficial effects of resveratrol on mitochondrial function The Role of SIRT1 in Diabetic Kidney Disease.Pharmacologic Means of Extending Lifespan.Role of SIRT1 in regulation of epithelial-to-mesenchymal transition in oral squamous cell carcinoma metastasis Histone/protein deacetylases control Foxp3 expression and the heat shock response of T-regulatory cells.Sirtuin 1: A Target for Kidney Diseases.Phenolic secoiridoids in extra virgin olive oil impede fibrogenic and oncogenic epithelial-to-mesenchymal transition: extra virgin olive oil as a source of novel antiaging phytochemicals.Resveratrol causes cell cycle arrest, decreased collagen synthesis, and apoptosis in rat intestinal smooth muscle cells Activation of Sirtuin-1 Promotes Renal Fibroblast Activation and Aggravates Renal Fibrogenesis The Histone Deacetylase Sirtuin 1 Is Reduced in Systemic Sclerosis and Abrogates Fibrotic Responses by Targeting Transforming Growth Factor β Signaling.Resveratrol has antiinflammatory and antifibrotic effects in the peptidoglycan-polysaccharide rat model of Crohn's disease.Transforming growth factor-β, bioenergetics, and mitochondria in renal disease Resveratrol inhibits epithelial-mesenchymal transition of retinal pigment epithelium and development of proliferative vitreoretinopathy Sirtuins and renal diseases: relationship with aging and diabetic nephropathy.Are sirtuins viable targets for improving healthspan and lifespan?Identification of sirtuin 1 as a promising therapeutic target for hypertrophic scars.Resveratrol suppresses myofibroblast activity of human buccal mucosal fibroblasts through the epigenetic inhibition of ZEB1 expression.Transcriptional repression of SIRT1 by protein inhibitor of activated STAT 4 (PIAS4) in hepatic stellate cells contributes to liver fibrosis.The Roles of SIRT1 in Cancer.A low-salt diet increases the expression of renal sirtuin 1 through activation of the ghrelin receptor in rats.Downregulation of angiotensin type 1 receptor and nuclear factor-κB by sirtuin 1 contributes to renoprotection in unilateral ureteral obstruction.Suberoylanilide hydroxamic acid attenuates paraquat-induced pulmonary fibrosis by preventing Smad7 from deacetylation in rats.SIRT1 suppresses the epithelial-to-mesenchymal transition in cancer metastasis and organ fibrosis.Resveratrol inhibits transforming growth factor-β2-induced epithelial-to-mesenchymal transition in human retinal pigment epithelial cells by suppressing the Smad pathway.Reducing Smad3/ATF4 was essential for Sirt1 inhibiting ER stress-induced apoptosis in mice brown adipose tissue SirT1 activator represses the transcription of TNF‑α in THP‑1 cells of a sepsis model via deacetylation of H4K16.Resveratrol inhibits collagen I synthesis by suppressing IGF-1R activation in intestinal fibroblasts Cellular and molecular effects of sirtuins in health and disease.Anti-aging molecule, Sirt1: a novel therapeutic target for diabetic nephropathy.Targeted therapies for systemic sclerosis.Nephroprotective action of sirtuin 1 (SIRT1).

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Resveratrol inhibits renal fibrosis in the obstructed kidney: potential role in deacetylation of Smad3

http://www.wikidata.org/entity/Q34086829

description

2010 nî lūn-bûn

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2010 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2010 թվականի հուլիսին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Resveratrol inhibits renal fib ...... role in deacetylation of Smad3

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Resveratrol inhibits renal fib ...... role in deacetylation of Smad3

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Resveratrol inhibits renal fib ...... role in deacetylation of Smad3

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type

label

Resveratrol inhibits renal fib ...... role in deacetylation of Smad3

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Resveratrol inhibits renal fib ...... role in deacetylation of Smad3

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Resveratrol inhibits renal fib ...... role in deacetylation of Smad3

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prefLabel

Resveratrol inhibits renal fib ...... role in deacetylation of Smad3

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Resveratrol inhibits renal fib ...... role in deacetylation of Smad3

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Resveratrol inhibits renal fib ...... role in deacetylation of Smad3

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AJPATH.2010.090923

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The American Journal of Pathology

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Resveratrol inhibits renal fib ...... role in deacetylation of Smad3

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Xinli Qu

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Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase.

Lysine acetylation: codified crosstalk with other posttranslational modifications

SIRT1 inhibits transforming growth factor beta-induced apoptosis in glomerular mesangial cells via Smad7 deacetylation

Therapeutic potential of resveratrol: the in vivo evidence

Histone acetyltransferases

Resveratrol, a polyphenol found in wine, reduces ischemia reperfusion injury in rat kidneys.

The transcriptional coactivator and acetyltransferase p300 in fibroblast biology and fibrosis.

Inhibition of p38 mitogen-activated protein kinase and transforming growth factor-beta1/Smad signaling pathways modulates the development of fibrosis in adriamycin-induced nephropathy.

Smad3 as a mediator of the fibrotic response.

Transforming growth factor-beta and Smad signalling in kidney diseases.

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Sharon D. Ricardo

John F. Bertram

David J Nikolic-Paterson

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