Implications of Proprotein Convertases in Ovarian Cancer Cell Proliferation and Tumor Progression: Insights for PACE4 as a Therapeutic Target.

Implications of Proprotein Convertases in Ovarian Cancer Cell Proliferation and Tumor Progression: Insights for PACE4 as a Therapeutic Target.

Item
http://www.wikidata.org/entity/Q34092195
Cationic Cell-Penetrating Peptides Are Potent Furin Inhibitors.Expression of paired basic amino acid-cleaving enzyme 4 (PACE4) correlated with prognosis in non-small cell lung cancer (NSCLC) patients.Identification of potent and compartment-selective small molecule furin inhibitors using cell-based assays.Liver-Specific Inactivation of the Proprotein Convertase FURIN Leads to Increased Hepatocellular Carcinoma Growth.PACE4 regulates apoptosis in human prostate cancer cells via endoplasmic reticulum stress and mitochondrial signaling pathways.Multi-Leu PACE4 Inhibitor Retention within Cells Is PACE4 Dependent and a Prerequisite for Antiproliferative Activity.PACE4 inhibitors and their peptidomimetic analogs block prostate cancer tumor progression through quiescence induction, increased apoptosis and impaired neovascularisation.PACE4-based molecular targeting of prostate cancer using an engineered ⁶⁴Cu-radiolabeled peptide inhibitor.The proprotein convertase furin in tumour progression.A multiplex platform for the identification of ovarian cancer biomarkersRational Design of a Highly Potent and Selective Peptide Inhibitor of PACE4 by Salt Bridge Interaction with D160 at Position P3.Furin inhibitor D6R suppresses epithelial-mesenchymal transition in SW1990 and PaTu8988 cells via the Hippo-YAP signaling pathway.Proprotein convertase subtilisin/kexin type 6 activates the extracellular signal-regulated kinase 1/2 and Wnt family member 3A pathways and promotes in vitro proliferation, migration and invasion of breast cancer MDA-MB-231 cells.Evaluation of PACE4 isoforms as biomarkers in thyroid cancer
P2860

Implications of Proprotein Convertases in Ovarian Cancer Cell Proliferation and Tumor Progression: Insights for PACE4 as a Therapeutic Target.

Item
http://www.wikidata.org/entity/Q34092195
description
2014 nî lūn-bûn
@nan
2014 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Implications of Proprotein Con ...... PACE4 as a Therapeutic Target.
@ast
Implications of Proprotein Con ...... PACE4 as a Therapeutic Target.
@en
Implications of Proprotein Con ...... PACE4 as a Therapeutic Target.
@nl
type
label
Implications of Proprotein Con ...... PACE4 as a Therapeutic Target.
@ast
Implications of Proprotein Con ...... PACE4 as a Therapeutic Target.
@en
Implications of Proprotein Con ...... PACE4 as a Therapeutic Target.
@nl
prefLabel
Implications of Proprotein Con ...... PACE4 as a Therapeutic Target.
@ast
Implications of Proprotein Con ...... PACE4 as a Therapeutic Target.
@en
Implications of Proprotein Con ...... PACE4 as a Therapeutic Target.
@nl
P1433
P1476
P2093
P2860
P31
P356
P50
P577
P5875
P698
P921
P932
P356
P1433
P1476
Implications of Proprotein Con ...... PACE4 as a Therapeutic Target
@en
P2093
P2860
P31
P356
10.1016/J.TRANON.2014.04.008
P50
P577
P5875
P698
P921
P932