Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells.
about
"Off-Spotter": very fast and exhaustive enumeration of genomic lookalikes for designing CRISPR/Cas guide RNAsCRISPR/Cas9-mediated gene editing in human tripronuclear zygotesGenome Engineering with TALE and CRISPR Systems in NeuroscienceBrain tumor modeling using the CRISPR/Cas9 system: state of the art and view to the futureThe Rise of CRISPR/Cas for Genome Editing in Stem CellsGenome-editing Technologies for Gene and Cell TherapyNuclease Target Site Selection for Maximizing On-target Activity and Minimizing Off-target Effects in Genome EditingAdvanced In vivo Use of CRISPR/Cas9 and Anti-sense DNA Inhibition for Gene Manipulation in the BrainBiochemical Analysis of Genome Functions Using Locus-Specific Chromatin Immunoprecipitation TechnologiesBeyond editing: repurposing CRISPR-Cas9 for precision genome regulation and interrogationResources for the design of CRISPR gene editing experimentsHow specific is CRISPR/Cas9 really?Minimizing off-Target Mutagenesis Risks Caused by Programmable NucleasesA new age in functional genomics using CRISPR/Cas9 in arrayed library screeningApplications of Engineered DNA-Binding Molecules Such as TAL Proteins and the CRISPR/Cas System in Biology ResearchThe utility of transposon mutagenesis for cancer studies in the era of genome editing.Enabling functional genomics with genome engineeringCRISPR-Cas9: A Revolutionary Tool for Cancer ModellingIsolation of Specific Genomic Regions and Identification of Their Associated Molecules by Engineered DNA-Binding Molecule-Mediated Chromatin Immunoprecipitation (enChIP) Using the CRISPR System and TAL ProteinsThe New State of the Art: Cas9 for Gene Activation and RepressionBreaking bad: The mutagenic effect of DNA repairOff-target Effects in CRISPR/Cas9-mediated Genome EngineeringMeasuring and Reducing Off-Target Activities of Programmable Nucleases Including CRISPR-Cas9Quantifying on- and off-target genome editingGenetic screens and functional genomics using CRISPR/Cas9 technologySTRUCTURAL BIOLOGY. A Cas9-guide RNA complex preorganized for target DNA recognitionCRISPR-Cas9: from Genome Editing to Cancer ResearchEditing the Neuronal Genome: a CRISPR View of Chromatin Regulation in Neuronal Development, Function, and PlasticityFunctional annotation of cis-regulatory elements in human cells by dCas9/sgRNABacterial CRISPR/Cas DNA endonucleases: A revolutionary technology that could dramatically impact viral research and treatmentDevelopment and applications of CRISPR-Cas9 for genome engineering.IFI16 restricts HSV-1 replication by accumulating on the hsv-1 genome, repressing HSV-1 gene expression, and directly or indirectly modulating histone modificationsCRISPR/Cas9-Mediated Genome Editing of Herpesviruses Limits Productive and Latent InfectionsExploiting the CRISPR/Cas9 PAM Constraint for Single-Nucleotide Resolution InterventionsA Biophysical Model of CRISPR/Cas9 Activity for Rational Design of Genome Editing and Gene RegulationRNAi screening comes of age: improved techniques and complementary approachesFusion of catalytically inactive Cas9 to FokI nuclease improves the specificity of genome modificationLive cell imaging of low- and non-repetitive chromosome loci using CRISPR-Cas9Cas9-chromatin binding information enables more accurate CRISPR off-target prediction.A novel two-step genome editing strategy with CRISPR-Cas9 provides new insights into telomerase action and TERT gene expression.
P2860
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P2860
Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells.
description
2014 nî lūn-bûn
@nan
2014 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells.
@ast
Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells.
@en
Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells.
@nl
type
label
Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells.
@ast
Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells.
@en
Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells.
@nl
prefLabel
Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells.
@ast
Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells.
@en
Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells.
@nl
P2093
P2860
P50
P356
P1433
P1476
Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells.
@en
P2093
Albert W Cheng
Alexandro E Trevino
Andrea J Kriz
Anthony C Chiu
Daniel B Dadon
David A Scott
Feng Zhang
Phillip A Sharp
Silvana Konermann
P2860
P2888
P304
P356
10.1038/NBT.2889
P577
2014-04-20T00:00:00Z