Application of a physiologically based pharmacokinetic model informed by a top-down approach for the prediction of pharmacokinetics in chronic kidney disease patients.
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Physiologically Based Pharmacokinetic (PBPK) Modeling and Simulation Approaches: A Systematic Review of Published Models, Applications, and Model VerificationA physiologically based pharmacokinetic drug-disease model to predict carvedilol exposure in adult and paediatric heart failure patients by incorporating pathophysiological changes in hepatic and renal blood flowsInfluence of chronic kidney disease and haemodialysis treatment on pharmacokinetics of nebivolol enantiomersDelineating the Role of Various Factors in Renal Disposition of Digoxin through Application of Physiologically Based Kidney Model to Renal Impairment Populations.PBPK Modeling of the Effect of Reduced Kidney Function on the Pharmacokinetics of Drugs Excreted Renally by Organic Anion Transporters.Systematic and quantitative assessment of the effect of chronic kidney disease on CYP2D6 and CYP3A4/5.Organ Impairment-Drug-Drug Interaction Database: A Tool for Evaluating the Impact of Renal or Hepatic Impairment and Pharmacologic Inhibition on the Systemic Exposure of Drugs.Pharmacodynamic analysis of target-controlled infusion of propofol in patients with hepatic insufficiency.Effect of Chronic Kidney Disease on Nonrenal Elimination Pathways: A Systematic Assessment of CYP1A2, CYP2C8, CYP2C9, CYP2C19, and OATP.Evaluation of Model-Based Prediction of Pharmacokinetics in the Renal Impairment Population.Physiologically Based Pharmacokinetic Model Qualification and Reporting Procedures for Regulatory Submissions: A Consortium Perspective.The Role of the Kidney in Drug Elimination: Transport, Metabolism, and the Impact of Kidney Disease on Drug Clearance.
P2860
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P2860
Application of a physiologically based pharmacokinetic model informed by a top-down approach for the prediction of pharmacokinetics in chronic kidney disease patients.
description
2014 nî lūn-bûn
@nan
2014 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Application of a physiological ...... ronic kidney disease patients.
@ast
Application of a physiological ...... ronic kidney disease patients.
@en
Application of a physiological ...... ronic kidney disease patients.
@nl
type
label
Application of a physiological ...... ronic kidney disease patients.
@ast
Application of a physiological ...... ronic kidney disease patients.
@en
Application of a physiological ...... ronic kidney disease patients.
@nl
prefLabel
Application of a physiological ...... ronic kidney disease patients.
@ast
Application of a physiological ...... ronic kidney disease patients.
@en
Application of a physiological ...... ronic kidney disease patients.
@nl
P2093
P2860
P1433
P1476
Application of a physiological ...... ronic kidney disease patients.
@en
P2093
Hiroaki Takubo
Hiroshi Komura
Hiroyuki Sayama
Masahiro Iwaki
Motohiro Kogayu
P2860
P2888
P304
P356
10.1208/S12248-014-9626-3
P407
P577
2014-06-11T00:00:00Z
P6179
1011994240