Functional variation of MC1R alleles from red-haired individuals.
about
Aberrant trafficking of human melanocortin 1 receptor variants associated with red hair and skin cancer: Steady-state retention of mutant forms in the proximal golgiThe genetics of sun sensitivity in humans.Anesthetic requirement is increased in redheads.Women with red hair report a slightly increased rate of bruising but have normal coagulation testsGenetic variants in pigmentation genes, pigmentary phenotypes, and risk of skin cancer in CaucasiansIncreased sensitivity to thermal pain and reduced subcutaneous lidocaine efficacy in redheadsThe melanocortin-1 receptor gene mediates female-specific mechanisms of analgesia in mice and humansUV-induced expression of key component of the tanning process, the POMC and MC1R genes, is dependent on the p-38-activated upstream stimulating factor-1 (USF-1)Long human CHGA flanking chromosome 14 sequence required for optimal BAC transgenic "rescue" of disease phenotypes in the mouse Chga knockout.Genome-wide scans for footprints of natural selection.Elevated plasma levels of the pituitary hormone Cthrc1 in individuals with red hair but not in patients with solid tumorsHypertension from targeted ablation of chromogranin A can be rescued by the human orthologMC1R mutations modify the classic phenotype of oculocutaneous albinism type 2 (OCA2)Beta-catenin activity in the dermal papilla of the hair follicle regulates pigment-type switching.Melanocortin-1 receptor structure and functional regulation.Screening of TYR, OCA2, GPR143, and MC1R in patients with congenital nystagmus, macular hypoplasia, and fundus hypopigmentation indicating albinism.Signaling from the human melanocortin 1 receptor to ERK1 and ERK2 mitogen-activated protein kinases involves transactivation of cKIT.Melanocortin MC₁ receptor in human genetics and model systems.A dominant-negative mutation of mouse Lmx1b causes glaucoma and is semi-lethal via LDB1-mediated dimerization [corrected].Variants of SCARB1 and VDR Involved in Complex Genetic Interactions May Be Implicated in the Genetic Susceptibility to Clear Cell Renal Cell CarcinomaMelanocortin 1 receptor genotype: an important determinant of the damage response of melanocytes to ultraviolet radiation.Melanocortin 1 receptor variants, pigmentation, and skin cancer susceptibility.Intraoperative awareness risk, anesthetic sensitivity, and anesthetic management for patients with natural red hair: a matched cohort study.Interaction between p53 codon 72 polymorphism and melanocortin 1 receptor variants on suntan response and cutaneous melanoma risk.Melanocortin 1 receptor variants: functional role and pigmentary associations.MC1R, the cAMP pathway, and the response to solar UV: extending the horizon beyond pigmentationAfamelanotide (CUV1647) in dermal phototoxicity of erythropoietic protoporphyria.Human melanocortin 1 receptor (MC1R) gene variants alter melanoma cell growth and adhesion to extracellular matrix.Variants of the melanocortin-1 receptor: do they matter clinically?MC1R expression in HaCaT keratinocytes inhibits UVA-induced ROS production via NADPH oxidase- and cAMP-dependent mechanisms.Identification and functional analysis of novel variants of the human melanocortin 1 receptor found in melanoma patients.Reciprocal responses of fibroblasts and melanocytes to α-MSH depending on MC1R polymorphisms.Agonist-independent, high constitutive activity of the human melanocortin 1 receptor.Functional melanocortin 1 receptor Mc1r is not necessary for an inflammatory response to UV radiation in adult mouse skin.Rate limiting factors in melanocortin 1 receptor signalling through the cAMP pathway.Not another type of potato: MC1R and the russet coloration of Burmese cats.Red hair and anesthetic requirement.Palmitoylation-dependent activation of MC1R prevents melanomagenesis.Long-term observational study of afamelanotide in 115 patients with erythropoietic protoporphyria.Melanocortin 1 receptor (MC1R) genotype influences erythemal sensitivity to psoralen-ultraviolet A photochemotherapy.
P2860
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P2860
Functional variation of MC1R alleles from red-haired individuals.
description
2001 nî lūn-bûn
@nan
2001 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Functional variation of MC1R alleles from red-haired individuals.
@ast
Functional variation of MC1R alleles from red-haired individuals.
@en
Functional variation of MC1R alleles from red-haired individuals.
@nl
type
label
Functional variation of MC1R alleles from red-haired individuals.
@ast
Functional variation of MC1R alleles from red-haired individuals.
@en
Functional variation of MC1R alleles from red-haired individuals.
@nl
prefLabel
Functional variation of MC1R alleles from red-haired individuals.
@ast
Functional variation of MC1R alleles from red-haired individuals.
@en
Functional variation of MC1R alleles from red-haired individuals.
@nl
P2093
P356
P1476
Functional variation of MC1R alleles from red-haired individuals
@en
P2093
P304
P356
10.1093/HMG/10.21.2397
P577
2001-10-01T00:00:00Z