Hydride transfer in liver alcohol dehydrogenase: quantum dynamics, kinetic isotope effects, and role of enzyme motion.
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Network of coupled promoting motions in enzyme catalysisEnzymes: An integrated view of structure, dynamics and functionAtomic-Resolution Structures of Horse Liver Alcohol Dehydrogenase with NAD + and Fluoroalcohols Define Strained Michaelis ComplexesEffects of Cavities at the Nicotinamide Binding Site of Liver Alcohol Dehydrogenase on Structure, Dynamics and CatalysisAt the dawn of the 21st century: Is dynamics the missing link for understanding enzyme catalysis?Perspective: Defining and quantifying the role of dynamics in enzyme catalysisDynamics of immobilized and native Escherichia coli dihydrofolate reductase by quasielastic neutron scatteringPerspective on Diabatic Models of Chemical Reactivity as Illustrated by the Gas-Phase S(N)2 Reaction of Acetate Ion with 1,2-DichloroethaneConformational changes and catalysis by alcohol dehydrogenase.Horse Liver Alcohol Dehydrogenase: Zinc Coordination and Catalysis.A Non-Orthogonal Block-Localized Effective Hamiltonian Approach for Chemical and Enzymatic Reactions.Studies of proton translocations in biological systems: simulating proton transport in carbonic anhydrase by EVB-based modelsKinetic isotope effects of L-Dopa decarboxylase.Hydride transfer catalysed by Escherichia coli and Bacillus subtilis dihydrofolate reductase: coupled motions and distal mutations.Multidimensional tunneling, recrossing, and the transmission coefficient for enzymatic reactionsAnalysis of Hydrogen Tunneling in an Enzyme Active Site using von Neumann MeasurementsHydrogen tunnelling in enzyme-catalysed H-transfer reactions: flavoprotein and quinoprotein systems.Enzymatic catalysis and transfers in solution. I. Theory and computations, a unified view.Inverse Temperature Dependence of Nuclear Quantum Effects in DNA Base Pairs.Elucidating solvent contributions to solution reactions with ab initio QM/MM methods.Extracellular zinc ion regulates transient receptor potential melastatin 5 (TRPM5) channel activation through its interaction with a pore loop domain.The enzyme aromatic amine dehydrogenase induces a substrate conformation crucial for promoting vibration that significantly reduces the effective potential energy barrier to proton transfer.Structural reorganization and preorganization in enzyme active sites: comparisons of experimental and theoretically ideal active site geometries in the multistep serine esterase reaction cycle.Hydrogen tunneling in enzymes and biomimetic models.On the mechanism of photoinduced dimer dissociation in the plant UVR8 photoreceptor.Coupled motions in enzyme catalysis.Enzymatic conformational fluctuations along the reaction coordinate of cytidine deaminase.Combining solvent isotope effects with substrate isotope effects in mechanistic studies of alcohol and amine oxidation by enzymesAn analysis of reaction pathways for proton tunnelling in methylamine dehydrogenaseTransition state theory can be used in studies of enzyme catalysis: lessons from simulations of tunnelling and dynamical effects in lipoxygenase and other systems.Enzymatic Kinetic Isotope Effects from First-Principles Path Sampling Calculations.Hybrid quantum/classical molecular dynamics for a proton transfer reaction coupled to a dissipative bath.Exploring the reversal of enantioselectivity on a zinc-dependent alcohol dehydrogenase.The EVB as a quantitative tool for formulating simulations and analyzing biological and chemical reactions.An Analysis of All the Relevant Facts and Arguments Indicates that Enzyme Catalysis Does Not Involve Large Contributions from Nuclear Tunneling.Structure-Reactivity Effects on Intrinsic Primary Kinetic Isotope Effects for Hydride Transfer Catalyzed by Glycerol-3-phosphate Dehydrogenase.Hybrid quantum/classical molecular dynamics simulations of the proton transfer reactions catalyzed by ketosteroid isomerase: analysis of hydrogen bonding, conformational motions, and electrostatics.Proton-transport mechanisms in cytochrome c oxidase revealed by studies of kinetic isotope effects.Contribution of Buried Distal Amino Acid Residues in Horse Liver Alcohol Dehydrogenase to Structure and Catalysis.A reevaluation of the origin of the rate acceleration for enzyme-catalyzed hydride transfer.
P2860
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P2860
Hydride transfer in liver alcohol dehydrogenase: quantum dynamics, kinetic isotope effects, and role of enzyme motion.
description
2001 nî lūn-bûn
@nan
2001 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Hydride transfer in liver alco ...... ts, and role of enzyme motion.
@ast
Hydride transfer in liver alco ...... ts, and role of enzyme motion.
@en
Hydride transfer in liver alco ...... ts, and role of enzyme motion.
@nl
type
label
Hydride transfer in liver alco ...... ts, and role of enzyme motion.
@ast
Hydride transfer in liver alco ...... ts, and role of enzyme motion.
@en
Hydride transfer in liver alco ...... ts, and role of enzyme motion.
@nl
prefLabel
Hydride transfer in liver alco ...... ts, and role of enzyme motion.
@ast
Hydride transfer in liver alco ...... ts, and role of enzyme motion.
@en
Hydride transfer in liver alco ...... ts, and role of enzyme motion.
@nl
P2093
P356
P1476
Hydride transfer in liver alco ...... ts, and role of enzyme motion.
@en
P2093
Agarwal PK
Billeter SR
Hammes-Schiffer S
Iordanov T
P304
11262-11272
P356
10.1021/JA011384B
P407
P577
2001-11-01T00:00:00Z