Eph receptors and ephrin ligands: embryogenesis to tumorigenesis.
about
Role of microRNA-26b in glioma development and its mediated regulation on EphA2Eph receptors and ephrin ligands: important players in angiogenesis and tumor angiogenesisSoluble Jagged 1 represses the function of its transmembrane form to induce the formation of the Src-dependent chord-like phenotypeTyrosine phosphorylation of the well packed ephrinB cytoplasmic beta-hairpin for reverse signaling. Structural consequences and binding propertiesStructural insight into the binding diversity between the Tyr-phosphorylated human ephrinBs and Nck2 SH2 domainStructural and biophysical characterization of the EphB4*ephrinB2 protein-protein interaction and receptor specificityEphB1 associates with Grb7 and regulates cell migrationEphA2 mediates ligand-dependent inhibition and ligand-independent promotion of cell migration and invasion via a reciprocal regulatory loop with AktCharacterization of the human ephrin-A4 promoterInteractions between Eph kinases and ephrins provide a mechanism to support platelet aggregation once cell-to-cell contact has occurred.Tyrosine phosphorylation acts as a molecular switch to full-scale activation of the eIF2alpha RNA-dependent protein kinase.The level of TACI gene expression in myeloma cells is associated with a signature of microenvironment dependence versus a plasmablastic signatureDifferential regulation of EphA2 in normal and malignant cellsReceptor protein tyrosine kinase EphB4 is up-regulated in colon cancerVaccination with EphA2-derived T cell-epitopes promotes immunity against both EphA2-expressing and EphA2-negative tumorsEphA receptor signaling--complexity and emerging themesInjury-associated reacquiring of intestinal stem cell functionStructure of the ligand-binding domain of the EphB2 receptor at 2 Å resolutionSignals from Eph and ephrin proteins: a developmental tool kitActivation of the EphA2 tyrosine kinase stimulates the MAP/ERK kinase signaling cascadeManipulation of EphB2 regulatory motifs and SH2 binding sites switches MAPK signaling and biological activityAdaptor protein Crk is required for ephrin-B1-induced membrane ruffling and focal complex assembly of human aortic endothelial cells.Dissecting the EphA3/Ephrin-A5 interactions using a novel functional mutagenesis screen.EphB2/R-Ras signaling regulates glioma cell adhesion, growth, and invasion.Over-expression of Eph and ephrin genes in advanced ovarian cancer: ephrin gene expression correlates with shortened survival.Nanoscale obstacle arrays frustrate transport of EphA2-Ephrin-A1 clusters in cancer cell linesSpecific tumor delivery of paclitaxel using glycolipid-like polymer micelles containing gold nanospheresEphrin B2 and EphB4 selectively mark arterial and venous vessels in cerebral arteriovenous malformation.Rac-dependent trans-endocytosis of ephrinBs regulates Eph-ephrin contact repulsion.Identification of target actin content and polymerization status as a mechanism of tumor resistance after cytolytic T lymphocyte pressure.Effective photothermal chemotherapy using doxorubicin-loaded gold nanospheres that target EphB4 receptors in tumors.The many faces of metalloproteases: cell growth, invasion, angiogenesis and metastasis.Inhibition of tumor growth and angiogenesis by soluble EphB4.Inhibition of VEGF-dependent multistage carcinogenesis by soluble EphA receptors.Diverse roles for the Eph family of receptor tyrosine kinases in carcinogenesis.Peptide-conjugated polymeric micellar nanoparticles for Dual SPECT and optical imaging of EphB4 receptors in prostate cancer xenografts.Targeting pancreatic islets with phage display assisted by laser pressure catapult microdissection.EphA2 overexpression is associated with lack of hormone receptor expression and poor outcome in endometrial cancer.Hsp90 is an essential regulator of EphA2 receptor stability and signaling: implications for cancer cell migration and metastasis.Receptor tyrosine kinase EphB4 is a survival factor in breast cancer.
P2860
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P2860
Eph receptors and ephrin ligands: embryogenesis to tumorigenesis.
description
2000 nî lūn-bûn
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2000 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Eph receptors and ephrin ligands: embryogenesis to tumorigenesis.
@ast
Eph receptors and ephrin ligands: embryogenesis to tumorigenesis.
@en
Eph receptors and ephrin ligands: embryogenesis to tumorigenesis.
@nl
type
label
Eph receptors and ephrin ligands: embryogenesis to tumorigenesis.
@ast
Eph receptors and ephrin ligands: embryogenesis to tumorigenesis.
@en
Eph receptors and ephrin ligands: embryogenesis to tumorigenesis.
@nl
prefLabel
Eph receptors and ephrin ligands: embryogenesis to tumorigenesis.
@ast
Eph receptors and ephrin ligands: embryogenesis to tumorigenesis.
@en
Eph receptors and ephrin ligands: embryogenesis to tumorigenesis.
@nl
P2860
P356
P1433
P1476
Eph receptors and ephrin ligands: embryogenesis to tumorigenesis.
@en
P2093
Dodelet VC
Pasquale EB
P2860
P2888
P304
P356
10.1038/SJ.ONC.1203856
P407
P577
2000-11-01T00:00:00Z
P5875
P6179
1045452150