about
Pathophysiological power of improper tonic GABA(A) conductances in mature and immature models.Mechanisms Underlying Tolerance after Long-Term Benzodiazepine Use: A Future for Subtype-Selective GABA(A) Receptor Modulators?Insomnia pharmacotherapyStructural mechanisms underlying benzodiazepine modulation of the GABA(A) receptorThe anti-convulsant stiripentol acts directly on the GABA(A) receptor as a positive allosteric modulatorAllosteric potentiators of metabotropic glutamate receptor subtype 1a differentially modulate independent signaling pathways in baby hamster kidney cellsFunctional neuroanatomy of the noradrenergic locus coeruleus: its roles in the regulation of arousal and autonomic function part II: physiological and pharmacological manipulations and pathological alterations of locus coeruleus activity in humansA selective allosteric potentiator of the M1 muscarinic acetylcholine receptor increases activity of medial prefrontal cortical neurons and restores impairments in reversal learningDiscovery and characterization of novel allosteric potentiators of M1 muscarinic receptors reveals multiple modes of activity.Antianxiety and antidepressant-like effects of AC-5216, a novel mitochondrial benzodiazepine receptor ligandNootropic alpha7 nicotinic receptor allosteric modulator derived from GABAA receptor modulatorsDrugs for allosteric sites on receptorsRapid Antidepressant Action and Restoration of Excitatory Synaptic Strength After Chronic Stress by Negative Modulators of Alpha5-Containing GABAA Receptors.Anxioselective anxiolytics: on a quest for the Holy GrailExploiting protein flexibility to predict the location of allosteric sitesAltered pharmacology and GABA-A receptor subunit expression in dorsal midline thalamic neurons in limbic epilepsyAllosteric modulation of metabotropic glutamate receptors.Benzodiazepine-induced anxiolysis and reduction of conditioned fear are mediated by distinct GABAA receptor subtypes in miceBeyond classical benzodiazepines: novel therapeutic potential of GABAA receptor subtypes.The biology of fear- and anxiety-related behaviorsDevelopmental hearing loss disrupts synaptic inhibition: implications for auditory processing.Reduced conditioned fear response in mice that lack Dlx1 and show subtype-specific loss of interneuronsAntagonism of the ethanol-like discriminative stimulus effects of ethanol, pentobarbital, and midazolam in cynomolgus monkeys reveals involvement of specific GABA(A) receptor subtypes.Inhibitory neurotransmission, plasticity and aging in the mammalian central auditory system.Amygdala-specific reduction of alpha1-GABAA receptors disrupts the anticonvulsant, locomotor, and sedative, but not anxiolytic, effects of benzodiazepines in mice.Drugs for sleep disorders: mechanisms and therapeutic prospectsRelationship between sedation and pupillary function: comparison of diazepam and diphenhydramine.Modulation of gamma-aminobutyric acid type A receptor-mediated spontaneous inhibitory postsynaptic currents in auditory cortex by midazolam and isofluraneComparison of the effects of the GABAB receptor positive modulator BHF177 and the GABAB receptor agonist baclofen on anxiety-like behavior, learning, and memory in miceExpression of GABA A receptor alpha1 subunit mRNA and protein in rat neocortex following photothrombotic infarction.A substituted anilino enaminone acts as a novel positive allosteric modulator of GABA(A) receptors in the mouse brain.In search of allosteric modulators of a7-nAChR by solvent density guided virtual screening.Zolpidem modulation of phasic and tonic GABA currents in the rat dorsal motor nucleus of the vagus.Seven transmembrane receptors as shapeshifting proteins: the impact of allosteric modulation and functional selectivity on new drug discovery.Ramelteon: a novel hypnotic indicated for the treatment of insomniaMethylation of leukocyte DNA and ovarian cancer: relationships with disease status and outcome.Pachymic Acid Enhances Pentobarbital-Induced Sleeping Behaviors via GABAA-ergic Systems in MiceNeurosteroid withdrawal regulates GABA-A receptor α4-subunit expression and seizure susceptibility by activation of progesterone receptor-independent early growth response factor-3 pathwayBiocytin-labelling and its impact on late 20th century studies of cortical circuitry2013 Philip S. Portoghese Medicinal Chemistry Lectureship: drug discovery targeting allosteric sites.
P2860
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P2860
description
2002 nî lūn-bûn
@nan
2002 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
A new benzodiazepine pharmacology.
@ast
A new benzodiazepine pharmacology.
@en
A new benzodiazepine pharmacology.
@nl
type
label
A new benzodiazepine pharmacology.
@ast
A new benzodiazepine pharmacology.
@en
A new benzodiazepine pharmacology.
@nl
prefLabel
A new benzodiazepine pharmacology.
@ast
A new benzodiazepine pharmacology.
@en
A new benzodiazepine pharmacology.
@nl
P356
P1476
A new benzodiazepine pharmacology
@en
P2093
P356
10.1124/JPET.300.1.2
P407
P577
2002-01-01T00:00:00Z