Frequent ASXL2 mutations in acute myeloid leukemia patients with t(8;21)/RUNX1-RUNX1T1 chromosomal translocations.
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Acute Myeloid Leukemia: A Concise ReviewMolecular landscape of acute myeloid leukemia in younger adults and its clinical relevanceNovel Prognostic and Therapeutic Mutations in Acute Myeloid LeukemiaEpigenetics in normal and malignant hematopoiesis: An overview and update 2017.ASXL2 is essential for haematopoiesis and acts as a haploinsufficient tumour suppressor in leukemia.Comprehensive mutational profiling of core binding factor acute myeloid leukemia.Mutations in the CCND1 and CCND2 genes are frequent events in adult patients with t(8;21)(q22;q22) acute myeloid leukemiaLoss of Asxl2 leads to myeloid malignancies in miceThe genomic landscape of core-binding factor acute myeloid leukemiasASXL genes and RUNX1: an intimate connection?Functional proteomics of the epigenetic regulators ASXL1, ASXL2 and ASXL3: a convergence of proteomics and epigenetics for translational medicine.Clonal evolution in myelodysplastic syndromesDe novo dominant ASXL3 mutations alter H2A deubiquitination and transcription in Bainbridge-Ropers syndrome.Ancestral-derived effects on the mutational landscape of laryngeal cancer.UBASH3B/Sts-1-CBL axis regulates myeloid proliferation in human preleukemia induced by AML1-ETO.Diagnosis and management of AML in adults: 2017 ELN recommendations from an international expert panel.New insights into transcriptional and leukemogenic mechanisms of AML1-ETO and E2A fusion proteins.Clinical Relevance of RUNX1 and CBFB Alterations in Acute Myeloid Leukemia and Other Hematological Disorders.The Role of Additional Sex Combs-Like Proteins in Cancer.Role of RUNX1 in hematological malignancies.Acute myeloid leukaemia genomics.Whole-exome sequencing reveals the spectrum of gene mutations and the clonal evolution patterns in paediatric acute myeloid leukaemia.Acute myeloid leukemia with del(9q) is characterized by frequent mutations of NPM1, DNMT3A, WT1 and low expression of TLE4.Immortalization of human AE pre-leukemia cells by hTERT allows leukemic transformation.ZBTB7A mutations in acute myeloid leukaemia with t(8;21) translocation.Gene Mutations as Emerging Biomarkers and Therapeutic Targets for Relapsed Acute Myeloid Leukemia.ASXL2 mutations are frequently found in pediatric AML patients with t(8;21)/ RUNX1-RUNX1T1 and associated with a better prognosis.SNP-array lesions in core binding factor acute myeloid leukemia.RUNX1-ETO Leukemia.Recurrent Cytogenetic Abnormalities in Acute Myeloid Leukemia.Infrequent occurrence of TET1, TET3, and ASXL2 mutations in myelodysplastic/myeloproliferative neoplasms.Aberrant splicing and defective mRNA production induced by somatic spliceosome mutations in myelodysplasiaMolecular landscape and targeted therapy of acute myeloid leukemia
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Frequent ASXL2 mutations in acute myeloid leukemia patients with t(8;21)/RUNX1-RUNX1T1 chromosomal translocations.
description
2014 nî lūn-bûn
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2014 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
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name
Frequent ASXL2 mutations in acute myeloid leukemia patients with t
@nl
Frequent ASXL2 mutations in ac ...... T1 chromosomal translocations.
@ast
Frequent ASXL2 mutations in ac ...... T1 chromosomal translocations.
@en
type
label
Frequent ASXL2 mutations in acute myeloid leukemia patients with t
@nl
Frequent ASXL2 mutations in ac ...... T1 chromosomal translocations.
@ast
Frequent ASXL2 mutations in ac ...... T1 chromosomal translocations.
@en
prefLabel
Frequent ASXL2 mutations in acute myeloid leukemia patients with t
@nl
Frequent ASXL2 mutations in ac ...... T1 chromosomal translocations.
@ast
Frequent ASXL2 mutations in ac ...... T1 chromosomal translocations.
@en
P2093
P2860
P50
P1433
P1476
Frequent ASXL2 mutations in ac ...... 1T1 chromosomal translocations
@en
P2093
Aline Renneville
Catherine Lacombe
Eric Jourdan
Guy Leverger
Helene Lapillonne
Hervé Dombret
Jean-Baptiste Micol
Nicolas Boissel
Pascaline Etancelin
Sandrine Geffroy
P2860
P304
P356
10.1182/BLOOD-2014-04-571018
P407
P50
P577
2014-06-27T00:00:00Z