High nuclear expression levels of histone-modifying enzymes LSD1, HDAC2 and SIRT1 in tumor cells correlate with decreased survival and increased relapse in breast cancer patients.
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Sirtuin functions and modulation: from chemistry to the clinicTherapeutic opportunities in Ewing sarcoma: EWS-FLI inhibition via LSD1 targetingKDM1 class flavin-dependent protein lysine demethylasesOver-expression of lysine-specific demethylase 1 predicts tumor progression and poor prognosis in human esophageal cancerSIRT1 expression is associated with poor prognosis of lung adenocarcinoma.Expression of Lysine-specific demethylase 1 in human epithelial ovarian cancer.Prognostic role of LSD1 in various cancers: evidence from a meta-analysismiR-708/LSD1 axis regulates the proliferation and invasion of breast cancer cells.LSD1 engages a corepressor complex for the activation of the estrogen receptor α by estrogen and cAMPSIRT1 promotes metastasis of human osteosarcoma cells.KDM1 histone lysine demethylases as targets for treatments of oncological and neurodegenerative disease.TCPs: privileged scaffolds for identifying potent LSD1 inhibitors for cancer therapy.ERRα induces H3K9 demethylation by LSD1 to promote cell invasion.Phosphorylation of LSD1 at Ser112 is crucial for its function in induction of EMT and metastasis in breast cancer.HDAC2 overexpression is a poor prognostic factor of breast cancer patients with increased multidrug resistance-associated protein expression who received anthracyclines therapy.Over-expression of Sirt1 contributes to chemoresistance and indicates poor prognosis in serous epithelial ovarian cancer (EOC).Obesity accelerates murine gastric cancer growth by modulating the Sirt1/YAP pathway.Hypoxia-inducible factor 1 alpha promotes cancer stem cells-like properties in human ovarian cancer cells by upregulating SIRT1 expressionThe prognostic role of Sirt1 expression in solid malignancies: a meta-analysis.ERRα protein is stabilized by LSD1 in a demethylation-independent manner.SIRT1 overexpression is an independent prognosticator for patients with esophageal squamous cell carcinoma.Targeting Cancer with PCPA-Drug Conjugates: LSD1 Inhibition-Triggered Release of 4-Hydroxytamoxifen.Downregulation of histone demethylase JMJD1C inhibits colorectal cancer metastasis through targeting ATF2.KDM1A microenvironment, its oncogenic potential, and therapeutic significance.SIRT1 and Estrogen Signaling Cooperation for Breast Cancer Onset and Progression
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P2860
High nuclear expression levels of histone-modifying enzymes LSD1, HDAC2 and SIRT1 in tumor cells correlate with decreased survival and increased relapse in breast cancer patients.
description
2014 nî lūn-bûn
@nan
2014 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2014年の論文
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2014年学术文章
@wuu
2014年学术文章
@zh-cn
2014年学术文章
@zh-hans
2014年学术文章
@zh-my
2014年学术文章
@zh-sg
2014年學術文章
@yue
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High nuclear expression levels ...... pse in breast cancer patients.
@ast
High nuclear expression levels ...... pse in breast cancer patients.
@en
High nuclear expression levels ...... pse in breast cancer patients.
@nl
type
label
High nuclear expression levels ...... pse in breast cancer patients.
@ast
High nuclear expression levels ...... pse in breast cancer patients.
@en
High nuclear expression levels ...... pse in breast cancer patients.
@nl
prefLabel
High nuclear expression levels ...... pse in breast cancer patients.
@ast
High nuclear expression levels ...... pse in breast cancer patients.
@en
High nuclear expression levels ...... pse in breast cancer patients.
@nl
P2093
P2860
P356
P1433
P1476
High nuclear expression levels ...... apse in breast cancer patients
@en
P2093
Anita Sajet
Anne Benard
Anneke Q van Hoesel
Cornelis J H van de Velde
Esther Bastiaannet
Esther M de Kruijf
Inès J Goossens-Beumer
N Geeske Dekker-Ensink
Remco S Derr
Vincent T H B M Smit
P2860
P2888
P356
10.1186/1471-2407-14-604
P407
P50
P577
2014-08-20T00:00:00Z
P5875
P6179
1020622501