Recent advances in the Biginelli dihydropyrimidine synthesis. New tricks from an old dog.
about
Multicomponent reactions: A simple and efficient route to heterocyclic phosphonatesFreezing the Bioactive Conformation to Boost Potency: The Identification of BAY 85-8501, a Selective and Potent Inhibitor of Human Neutrophil Elastase for Pulmonary DiseasesA new paradigm for designing ring construction strategies for green organic synthesis: implications for the discovery of multicomponent reactions to build molecules containing a single ringSynthesis of sydnone substituted Biginelli derivatives as hyaluronidase inhibitors.Small-molecule and mutational analysis of allosteric Eg5 inhibition by monastrolStudies toward a library of tetrahydrofurans: click and MCR products of mono- and bis-tetrahydrofuransGold catalyzed cyclization of alkyne-tethered dihydropyrimidonesDesign, synthesis, and computational studies on dihydropyrimidine scaffolds as potential lipoxygenase inhibitors and cancer chemopreventive agents.1-(3-Fluoro-phen-yl)-4,4,6-trimethyl-3,4-dihydro-pyrimidine-2(1H)-thione.Methyl 6-(4-chloro-phen-yl)-2,4-dimethyl-1,3-dioxo-1,2,3,4,6,6a,7,12b-octa-hydro-chromeno[4',3':4,5]pyrano[2,3-d]pyrimidine-6a-carboxyl-ateVanillic aldehydes for the one-pot synthesis of novel 2-oxo-1,2,3,4-tetrahydropyrimidines.Asymmetric multicomponent reactions (AMCRs): the new frontier.Synthesis and evaluation of 1,2,4-triazolo[1,5-a]pyrimidines as antibacterial agents against Enterococcus faeciumThe impact of microwave synthesis on drug discovery.Green approach—multicomponent production of boron—containing hantzsch and biginelli esters.Evaluation of small-molecule modulators of the luteinizing hormone/choriogonadotropin and thyroid stimulating hormone receptors: structure-activity relationships and selective binding patterns.Cationic dirhodium carboxylate-catalyzed synthesis of dihydropyrimidones from propargyl ureas.Efficient synthesis of dihydropyrimidinones via a three-component Biginelli-type reaction of urea, alkylaldehyde and arylaldehyde.Recent developments in asymmetric multicomponent reactions.Synthesis of diverse dihydropyrimidine-related scaffolds by fluorous benzaldehyde-based Biginelli reaction and post-condensation modifications.An overview of molecular hybrids in drug discovery.Synthesis of some dihydropyrimidine-based compounds bearing pyrazoline moiety and evaluation of their antiproliferative activity.Synthesis and evaluation of 3,4-dihydropyrimidin-2(1H)-ones as sodium iodide symporter inhibitors.Synthesis and biological evaluation of novel homocamptothecins conjugating with dihydropyrimidine derivatives as potent topoisomerase I inhibitors.Synthesis of anionic phosphorus-containing heterocycles by intramolecular cyclizations involving N-functionalized phosphinecarboxamides.Capture-Collapse Heterocyclization: 1,3-Diazepanes by C-N Reductive Elimination from Rhodacyclopentanones.An Efficient One-Pot Green Protocol for the Synthesis of 5-Unsubstituted 3,4-Dihydropyrimidin-2(1H)-Ones Using Recyclable Amberlyst 15 DRY as a Heterogeneous Catalyst via Three-Component Biginelli-Like Reaction.1-(3-Chloro-phen-yl)-4,4,6-trimethyl-3,4-dihydro-pyrimidine-2(1H)-thione.Crystal structure of methyl 4-(2-fluoro-phenyl)-6-methyl-2-sulfanylidene-1,2,3,4-tetra-hydro-pyrimidine-5-carb-oxy-late.Enantioselective rhodium-catalyzed [4+2] cycloaddition of α,β-unsaturated imines and isocyanates.Synthesis, antibacterial studies, and molecular modeling studies of 3,4-dihydropyrimidinone compounds.Secondary amine-initiated three-component synthesis of 3,4-dihydropyrimidinones and thiones involving alkynes, aldehydes and thiourea/urea.Enantioselective synthesis of SNAP-7941: chiral dihydropyrimidone inhibitor of MCH1-R.1-(4-Chloro-phen-yl)-4,4,6-trimethyl-3,4-dihydro-pyrimidine-2(1H)-thione.Three Component Reaction: An Efficient Synthesis and Reactions of 3,4-Dihydropyrimidin-2(1H)-Ones and Thiones Using New Natural CatalystZeolite catalyzed solvent-free one-pot synthesis of dihydropyrimidin-2(1H)-ones--a practical synthesis of monastrol.Mechanochemical synthesis of small organic molecules.5,5'-Methylenebis[6-amino-3-methyl-2-methylsulfanylpyrimidin-4(3H)-one]: an unusual molecular geometry within a hydrogen-bonded molecular ribbon.Synthesis and carbonic anhydrase inhibitory properties of novel 1,4-dihydropyrimidinone substituted diarylureas.Synthesis of tetrahydropyrimidin-2-ones via FeCl3 catalyzed one-pot domino reaction of amines, methyl propiolate, aromatic aldehydes, and urea.
P2860
Q26738947-F28CD348-A8B6-457C-92E0-10AB0A0F1C4FQ28646482-8B35EDCC-AE25-4F0F-BBAF-E2F2625301C4Q28817207-208B261A-02E6-4B09-99A9-A4D076B41CBEQ30352525-F20E3D46-8A9C-4C0F-9BB1-E703BFE7F17CQ30477178-A7296FFC-8801-4372-9CA0-01BDA4A82CD3Q33627928-444031FA-2ADF-4160-81E5-463EF8319B52Q33958635-C230A7E3-D1D7-455A-A629-F5A1D0366FF2Q35115273-9B2ABB1A-25F7-4565-8C06-63F7E9810595Q35152821-84BB3814-394C-43CD-9BA5-BAEC9583AA1FQ35542258-4EC15B43-F75A-47AE-AD40-9A901DC79E39Q35910028-E83538DF-4714-4E5D-BFFA-873E3FD552C3Q36047385-8784163C-3736-4E97-87A7-07E62236687CQ36248215-541673EE-CA0E-4804-AD12-72A181150306Q36351705-87738CC0-0C6A-429B-BA4C-0CAE35491921Q36656022-B09DC951-3A24-4DEE-99BE-4C84B90326F4Q36891634-947218C7-3ABF-47A5-95C1-241E51A3CBE0Q36950576-1313BAC5-CCF1-4DC0-A738-4202FEF40F0DQ37406262-4686DE1A-3EC7-41D6-AF71-36685C69C463Q38006603-B6887A93-C9FE-4CC2-93FD-158FA65693C4Q38586663-6E358062-13EE-42B2-B757-1649763400BBQ38685830-4899A478-22E5-4805-B82F-DC1F740DA20CQ39070344-C40AC4B8-9D31-43BB-A246-85ACBB006D08Q39248523-8DE9EE18-8635-4620-9D52-574E7C77C73AQ39466335-2EBABC71-B75E-49B7-B4AB-5ACBC3BE1BFEQ39840000-1FD9D0FE-B83D-45F8-929F-8AAE348815EDQ41107892-27F5A842-BE30-4498-AAD5-F3E0D3D16C6AQ41771994-6B1ED9BF-A832-452A-84D2-66FC6C238335Q41837803-25431F34-D590-4B60-A9BC-635BBF023000Q41843331-B971E663-5F33-47E5-96BF-251408243279Q41845294-755B27AA-5734-4A5A-B629-C5E2A3D7066BQ42000149-30A8BB0F-53BC-4DA9-B045-38C3B97F2290Q42001421-E317A244-4367-4BB4-B1E4-9CA804DE35A3Q42185844-0EEC0386-19D7-4FEF-952E-CC502F7244B4Q42367084-E2AE19DF-49F4-4B1B-8BE2-8C4B4A3622B2Q42589913-B269910C-4C82-4B05-94AE-4846125B526CQ43171438-8FA77B8E-9EF6-43E6-892C-F7AE4E181854Q43254790-306B433A-E4CB-4951-9EBD-19A66EDF1470Q43594382-5DB7715F-EBD2-4F02-810C-F697AB9EA0BFQ43621607-2C07455A-E708-43FF-A49B-CDFF1D72AAE6Q43904790-DF3D2983-48F0-4B44-8B17-9ED322615313
P2860
Recent advances in the Biginelli dihydropyrimidine synthesis. New tricks from an old dog.
description
2000 nî lūn-bûn
@nan
2000 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Recent advances in the Biginelli dihydropyrimidine synthesis. New tricks from an old dog.
@ast
Recent advances in the Biginelli dihydropyrimidine synthesis. New tricks from an old dog.
@en
Recent advances in the Biginelli dihydropyrimidine synthesis. New tricks from an old dog.
@nl
type
label
Recent advances in the Biginelli dihydropyrimidine synthesis. New tricks from an old dog.
@ast
Recent advances in the Biginelli dihydropyrimidine synthesis. New tricks from an old dog.
@en
Recent advances in the Biginelli dihydropyrimidine synthesis. New tricks from an old dog.
@nl
prefLabel
Recent advances in the Biginelli dihydropyrimidine synthesis. New tricks from an old dog.
@ast
Recent advances in the Biginelli dihydropyrimidine synthesis. New tricks from an old dog.
@en
Recent advances in the Biginelli dihydropyrimidine synthesis. New tricks from an old dog.
@nl
P356
P1476
Recent advances in the Biginelli dihydropyrimidine synthesis. New tricks from an old dog
@en
P2093
P304
P356
10.1021/AR000048H
P407
P577
2000-12-01T00:00:00Z