Broad-spectrum antimicrobial peptides by rational combinatorial design and high-throughput screening: the importance of interfacial activity.
about
Computational modeling of membrane proteinsAn Integrated Framework Advancing Membrane Protein Modeling and DesignEvidence for Phenylalanine Zipper-Mediated Dimerization in the X-ray Crystal Structure of a Magainin 2 AnalogueA peptide derived from phage display library exhibits antibacterial activity against E. coli and Pseudomonas aeruginosaSynergistic antibacterial and anti-inflammatory activity of temporin A and modified temporin B in vivoSimulating the mechanism of antimicrobial lipopeptides with all-atom molecular dynamics.Callistemenonone A, a novel dearomatic dibenzofuran-type acylphloroglucinol with antimicrobial activity from Callistemon viminalis.Membrane binding of an acyl-lactoferricin B antimicrobial peptide from solid-state NMR experiments and molecular dynamics simulations.High-throughput discovery of broad-spectrum peptide antibiotics.Describing the mechanism of antimicrobial peptide action with the interfacial activity modelProgressive structuring of a branched antimicrobial peptide on the path to the inner membrane targetGain-of-function analogues of the pore-forming peptide melittin selected by orthogonal high-throughput screening.Structural features governing the activity of lactoferricin-derived peptides that act in synergy with antibiotics against Pseudomonas aeruginosa in vitro and in vivoHost defense peptides: an alternative as antiinfective and immunomodulatory therapeutics.Host Cell Interactions Are a Significant Barrier to the Clinical Utility of Peptide Antibiotics.A thermodynamic approach to the mechanism of cell-penetrating peptides in model membranesSynthetic molecular evolution of pore-forming peptides by iterative combinatorial library screening.pH Dependence of microbe sterilization by cationic antimicrobial peptidesToward the de novo design of antimicrobial peptides: Lack of correlation between peptide permeabilization of lipid vesicles and antimicrobial, cytolytic, or cytotoxic activity in living cells.Examination of bacterial inhibition using a catalytic DNAAntimicrobial activity of synthetic cationic peptides and lipopeptides derived from human lactoferricin against Pseudomonas aeruginosa planktonic cultures and biofilmsMembrane-Active Small Molecules: Designs Inspired by Antimicrobial Peptides.pH-Triggered, Macromolecule-Sized Poration of Lipid Bilayers by Synthetically Evolved Peptides.Lights, Camera, Action! Antimicrobial Peptide Mechanisms Imaged in Space and Time.Contribution of structural domains to the activity of ribonuclease 7 against uropathogenic bacteriaEffect of repetitive lysine-tryptophan motifs on the eukaryotic membrane.Hemolytic activity of membrane-active peptides correlates with the thermodynamics of binding to 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine bilayersDesigned supramolecular filamentous peptides: balance of nanostructure, cytotoxicity and antimicrobial activity.Multifunctional coatings to simultaneously promote osseointegration and prevent infection of orthopaedic implants.Direct cytosolic delivery of polar cargo to cells by spontaneous membrane-translocating peptides.The innate immune response during urinary tract infection and pyelonephritis.Toward Hemocompatible Self-assembling Antimicrobial Nanofibers: Understanding the Synergistic Effect of Supramolecular Structure and PEGylation on Hemocompatibility.Antimicrobial Peptide Potency is Facilitated by Greater Conformational Flexibility when Binding to Gram-negative Bacterial Inner Membranes.Small cationic antimicrobial peptides delocalize peripheral membrane proteins.A look at arginine in membranes.Antimicrobial peptides: successes, challenges and unanswered questions.Functionalization of biomolecules on nanoparticles: specialized for antibacterial applications.Amplifying renal immunity: the role of antimicrobial peptides in pyelonephritis.A bioinspired peptide scaffold with high antibiotic activity and low in vivo toxicityCovalent modification of a ten-residue cationic antimicrobial peptide with levofloxacin.
P2860
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P2860
Broad-spectrum antimicrobial peptides by rational combinatorial design and high-throughput screening: the importance of interfacial activity.
description
2009 nî lūn-bûn
@nan
2009 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Broad-spectrum antimicrobial p ...... tance of interfacial activity.
@ast
Broad-spectrum antimicrobial p ...... tance of interfacial activity.
@en
Broad-spectrum antimicrobial p ...... tance of interfacial activity.
@nl
type
label
Broad-spectrum antimicrobial p ...... tance of interfacial activity.
@ast
Broad-spectrum antimicrobial p ...... tance of interfacial activity.
@en
Broad-spectrum antimicrobial p ...... tance of interfacial activity.
@nl
prefLabel
Broad-spectrum antimicrobial p ...... tance of interfacial activity.
@ast
Broad-spectrum antimicrobial p ...... tance of interfacial activity.
@en
Broad-spectrum antimicrobial p ...... tance of interfacial activity.
@nl
P2093
P2860
P356
P1476
Broad-spectrum antimicrobial p ...... tance of interfacial activity.
@en
P2093
Ramesh Rathinakumar
William C Wimley
William F Walkenhorst
P2860
P304
P356
10.1021/JA8093247
P407
P577
2009-06-01T00:00:00Z