The monoamine oxidase A inhibitor clorgyline is a broad-spectrum inhibitor of fungal ABC and MFS transporter efflux pump activities which reverses the azole resistance of Candida albicans and Candida glabrata clinical isolates.
about
Inhibitors of the Candida albicans Major Facilitator Superfamily Transporter Mdr1p Responsible for Fluconazole ResistanceMicrobial efflux systems and inhibitors: approaches to drug discovery and the challenge of clinical implementationCandida infections and their prevention.A high throughput flow cytometric assay platform targeting transporter inhibitionDrug resistance is conferred on the model yeast Saccharomyces cerevisiae by expression of full-length melanoma-associated human ATP-binding cassette transporter ABCB5.Quinacrine inhibits Candida albicans growth and filamentation at neutral pH.Multidrug-resistant transporter mdr1p-mediated uptake of a novel antifungal compoundTranscriptional profile of Paracoccidioides induced by oenothein B, a potential antifungal agent from the Brazilian Cerrado plant Eugenia uniflora.The roles of CDR1, CDR2, and MDR1 in kaempferol-induced suppression with fluconazole-resistant Candida albicans.Quinone derivatives isolated from the endolichenic fungus Phialocephala fortinii are Mdr1 modulators that combat azole resistance in Candida albicans.The Role of Eukaryotic and Prokaryotic ABC Transporter Family in Failure of Chemotherapy.Antifungal adjuvants: Preserving and extending the antifungal arsenalThe effect of biomaterials and antifungals on biofilm formation by Candida species: a review.Medically important fungi respond to azole drugs: an update.The fungal resistome: a risk and an opportunity for the development of novel antifungal therapies.Targeting efflux pumps to overcome antifungal drug resistance.Synthetic Organotellurium Compounds Sensitize Drug-Resistant Candida albicans Clinical Isolates to Fluconazole.A subdose of fluconazole alters the virulence of Cryptococcus gattii during murine cryptococcosis and modulates type I interferon expression.Candidiasis and the impact of flow cytometry on antifungal drug discovery.Accumulation of Azole Drugs in the Fungal Plant Pathogen Magnaporthe oryzae Is the Result of Facilitated Diffusion Influx.Unexpected effects of azole transporter inhibitors on antifungal susceptibility in Candida glabrata and other pathogenic Candida species.Development of an accumulation assay and evaluation of the effects of efflux pump inhibitors on the retention of chlorhexidine digluconate in Pseudomonas aeruginosa and Staphylococcus aureus.Chemosensitization of multidrug resistant Candida albicans by the oxathiolone fused chalcone derivativesTwo inhibitors of yeast plasma membrane ATPase 1 (ScPma1p): toward the development of novel antifungal therapies.Dermatophyte Resistance to Antifungal Drugs: Mechanisms and Prospectus.
P2860
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P2860
The monoamine oxidase A inhibitor clorgyline is a broad-spectrum inhibitor of fungal ABC and MFS transporter efflux pump activities which reverses the azole resistance of Candida albicans and Candida glabrata clinical isolates.
description
2011 nî lūn-bûn
@nan
2011 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
The monoamine oxidase A inhibi ...... da glabrata clinical isolates.
@ast
The monoamine oxidase A inhibi ...... da glabrata clinical isolates.
@en
The monoamine oxidase A inhibi ...... da glabrata clinical isolates.
@nl
type
label
The monoamine oxidase A inhibi ...... da glabrata clinical isolates.
@ast
The monoamine oxidase A inhibi ...... da glabrata clinical isolates.
@en
The monoamine oxidase A inhibi ...... da glabrata clinical isolates.
@nl
prefLabel
The monoamine oxidase A inhibi ...... da glabrata clinical isolates.
@ast
The monoamine oxidase A inhibi ...... da glabrata clinical isolates.
@en
The monoamine oxidase A inhibi ...... da glabrata clinical isolates.
@nl
P2093
P2860
P356
P1476
The monoamine oxidase A inhibi ...... da glabrata clinical isolates.
@en
P2093
Ann R Holmes
Brian C Monk
Erwin Lamping
Irena Ivnitski-Steele
Larry A Sklar
Mikhail V Keniya
Richard D Cannon
P2860
P304
P356
10.1128/AAC.05706-11
P407
P577
2011-12-27T00:00:00Z