Coexpression of interleukin-12 chains by a self-splicing vector increases the protective cellular immune response of DNA and Mycobacterium bovis BCG vaccines against Mycobacterium tuberculosis
about
A second-generation anti TB vaccine is long overdueHost cell-induced components of the sulfate assimilation pathway are major protective antigens of Mycobacterium tuberculosis.Plasmid interleukin-23 (IL-23), but not plasmid IL-27, enhances the protective efficacy of a DNA vaccine against Mycobacterium tuberculosis infection.In vivo persistence and protective efficacy of the bacille Calmette Guerin vaccine overexpressing the HspX latency antigen.On the use of DNA vaccines for the prophylaxis of mycobacterial diseases.Mutations including IS6110 insertion in the gene encoding the MPB64 protein of Capilia TB-negative Mycobacterium tuberculosis isolatesCo-immunization of plasmid DNA encoding IL-12 and IL-18 with Bacillus Calmette-Guérin vaccine against progressive tuberculosisHow far have we reached in tuberculosis vaccine development?Secretion of functional monocyte chemotactic protein 3 by recombinant Mycobacterium bovis BCG attenuates vaccine virulence and maintains protective efficacy against M. tuberculosis infectionEffects of DNA- and Mycobacterium bovis BCG-based delivery of the Flt3 ligand on protective immunity to Mycobacterium tuberculosis.DNA vaccines against mycobacterial diseases.A multicistronic DNA vaccine induces significant protection against tuberculosis in mice and offers flexibility in the expressed antigen repertoireCytokine therapy of tuberculosis at the crossroads.Recombinant Mycobacterium bovis bacillus Calmette-Guérin (BCG) expressing mouse IL-18 augments Th1 immunity and macrophage cytotoxicity.Expression of a single-chain human interleukin-12 gene in transgenic tobacco plants and functional studies.Immunogenicity and protective efficacy conferred by a novel recombinant Mycobacterium bovis bacillus Calmette-Guérin strain expressing interleukin-12p70 of human cytokine and Ag85A of Mycobacterium tuberculosis fusion protein.Comparison of immune responses induced in mice by vaccination with DNA vaccine constructs expressing mycobacterial antigen 85A and interleukin-21 and Bacillus Galmette-Guérin.DNA vaccines against mycobacterial diseases
P2860
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P2860
Coexpression of interleukin-12 chains by a self-splicing vector increases the protective cellular immune response of DNA and Mycobacterium bovis BCG vaccines against Mycobacterium tuberculosis
description
2002 nî lūn-bûn
@nan
2002 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Coexpression of interleukin-12 ...... nst Mycobacterium tuberculosis
@ast
Coexpression of interleukin-12 ...... nst Mycobacterium tuberculosis
@en
Coexpression of interleukin-12 ...... nst Mycobacterium tuberculosis
@nl
type
label
Coexpression of interleukin-12 ...... nst Mycobacterium tuberculosis
@ast
Coexpression of interleukin-12 ...... nst Mycobacterium tuberculosis
@en
Coexpression of interleukin-12 ...... nst Mycobacterium tuberculosis
@nl
prefLabel
Coexpression of interleukin-12 ...... nst Mycobacterium tuberculosis
@ast
Coexpression of interleukin-12 ...... nst Mycobacterium tuberculosis
@en
Coexpression of interleukin-12 ...... nst Mycobacterium tuberculosis
@nl
P2093
P2860
P1476
Coexpression of interleukin-12 ...... nst Mycobacterium tuberculosis
@en
P2093
Arun T Kamath
Ela Martin
James A Triccas
Paul J Chaplin
Umaimainthan Palendira
Warwick J Britton
P2860
P304
P356
10.1128/IAI.70.4.1949-1956.2002
P407
P50
P577
2002-04-01T00:00:00Z