Factor V and thrombotic disease: description of a janus-faced protein.
about
Protein C anticoagulant and cytoprotective pathwaysStructural basis of coagulation factor V recognition for cleavage by RVV-VThe discovery of activated protein C resistanceCrystallization and preliminary X-ray crystallographic analysis of blood coagulation factor V-activating proteinase (RVV-V) from Russell's viper venomPolymorphisms at activated protein C cleavage sites of factor V: Are they important in the absence of factor V Leiden?Regulation of the protein C anticoagulant and antiinflammatory pathways.Theoretical and experimental study of the D2194G mutation in the C2 domain of coagulation factor V.Identification of the MMRN1 binding region within the C2 domain of human factor V.Effects of exogenous recombinant APC in mouse models of ischemia reperfusion injury and of atherosclerosis.Mac-1 directly binds to the endothelial protein C-receptor: a link between the protein C anticoagulant pathway and inflammation?New mechanisms for vascular control of inflammation mediated by natural anticoagulant proteins.Molecular recognition in the protein C anticoagulant pathway.Secretion of human protein C in mouse milkCoagulation, inflammation, and the risk of neonatal white matter damage.Blood coagulation and its regulation by anticoagulant pathways: genetic pathogenesis of bleeding and thrombotic diseases.The anticoagulant protein C pathway.Utility of testing for factor V Leiden.Inherited defects of coagulation Factor V: the thrombotic side.Coagulopathy and the role of recombinant human activated protein C in sepsis and following polytrauma.Inherited defects of coagulation factor V: the hemorrhagic side.Screening Outside the Catalytic Site: Inhibition of Macromolecular Inter-actions Through Structure-Based Virtual Ligand Screening Experiments.Genetic variations and their influence on risk and treatment of venous thrombosis.Factor Xa activation of factor V is of paramount importance in initiating the coagulation system: lessons from a tick salivary protein.Joint effects of cancer and variants in the factor 5 gene on the risk of venous thromboembolism.Novel insights into the regulation of coagulation by factor V isoforms, tissue factor pathway inhibitorα, and protein S.Factor V Leiden and prothrombin gene mutations in Egyptian cases with unexplained recurrent pregnancy loss.Mapping of the factor Xa binding site on factor Va by site-directed mutagenesisAtypical presentation of livedo racemosa in a factor V Leiden heterozygous positive patient with Pseudomonas aeruginosa urosepsis.Understanding Russell's viper venom factor V activator's substrate specificity by surface plasmon resonance and in-silico studies.α(1,3)-Fucosyltransferases FUT4 and FUT7 control murine susceptibility to thrombosis.Characterization of coagulation factor synthesis in nine human primary cell typesFactor VIII C1 domain spikes 2092-2093 and 2158-2159 comprise regions that modulate cofactor function and cellular uptake.Coagulation factor V(A2440G) causes east Texas bleeding disorder via TFPIα.Experimental melanoma metastasis in lungs of mice with congenital coagulation disorders.Thrombosis and inflammatory bowel disease-the role of genetic risk factors.The risk of venous thromboembolism associated with the factor V Leiden mutation and low B-vitamin status.Characterization of an immunologic polymorphism (D79H) in the heavy chain of factor V.Enhanced rate of cleavage at Arg-306 and Arg-506 in coagulation factor Va by Gla domain-mutated human-activated protein C.Does activated protein C-resistant factor V contribute to thrombin generation in hemophilic plasma?Factor Va residues 311-325 represent an activated protein C binding region.
P2860
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P2860
Factor V and thrombotic disease: description of a janus-faced protein.
description
2002 nî lūn-bûn
@nan
2002 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Factor V and thrombotic disease: description of a janus-faced protein.
@ast
Factor V and thrombotic disease: description of a janus-faced protein.
@en
Factor V and thrombotic disease: description of a janus-faced protein.
@nl
type
label
Factor V and thrombotic disease: description of a janus-faced protein.
@ast
Factor V and thrombotic disease: description of a janus-faced protein.
@en
Factor V and thrombotic disease: description of a janus-faced protein.
@nl
prefLabel
Factor V and thrombotic disease: description of a janus-faced protein.
@ast
Factor V and thrombotic disease: description of a janus-faced protein.
@en
Factor V and thrombotic disease: description of a janus-faced protein.
@nl
P1476
Factor V and thrombotic disease: description of a janus-faced protein.
@en
P2093
Björn Dahlbäck
Gerry A F Nicolaes
P304
P356
10.1161/01.ATV.0000012665.51263.B7
P407
P577
2002-04-01T00:00:00Z